The Transposon Registry

Displaying 321 - 340 of 2138
Tn6007
Dr Maurizio Labbate
Macquaarie University
  • Antispetic Resistance
Characteristics
Tn6007 is a 7.2-kb transposon, found as a part of Tn6006 in Enterobacter cloacae strain JKB7. It contained class1 integron, which contains two gene cassette. One of the cassettes carries qacE2b gene that predicted to confer antiseptic resistance.
References

Labbate M, Chowdhury PR, Stokes HW. A Class 1 Integron Present in a Human Commensal Has a Hybrid Transposition Module Compared to Tn402: Evidence of Interaction with Mobile DNA from Natural Environments. Journal of Bacteriology. 2008;190(15):5318-5327. DOI: 10.1128/JB.00199-08

Accession number
Contact
mlabbate@bio.mq.edu.au
Tn6008
Dr Maurizio Labbate
Macquaarie University
Characteristics
Tn6008 is a 6-kb transposon, found as a part of Tn6006 in Enterobacter cloacae strain JKB7. It contained 4 ORFs, an araC-like transcriptional regulator gene (JK010), an alkylhydroperoxidase-like gene (ahpD), a gene with an unknown function (JK011), and a lysR-like transcriptional regulator gene (JK012).
References

Labbate M, Chowdhury PR, Stokes HW. A Class 1 Integron Present in a Human Commensal Has a Hybrid Transposition Module Compared to Tn402: Evidence of Interaction with Mobile DNA from Natural Environments. Journal of Bacteriology. 2008;190(15):5318-5327. DOI: 10.1128/JB.00199-08

Accession number
Contact
mlabbate@bio.mq.edu.au
Tn6009
Dr Olusegun Soge
University of Washington
  • Antibiotic Resistance
  • Tetracycline
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6009 composed of a Tn916 linked to a Staphylococcus aureus mer operon in representative Gram-positive and Gram-negative bacteria isolated in Nigeria and Portugal.
References

Soge OO, Beck NK, White TM, No DB, Roberts MC. A novel transposon, Tn6009, composed of a Tn916 element linked with a Staphylococcus aureus mer operon. Journal of Antimicrobial Chemotherapy. 2008;62(4):674-680. DOI: 10.1093/jac/dkn255.

Accession number
Contact
sogeo@u.washington.edu
Tn6010
Mr Anders Norman
University of Copenhagen
  • Antibiotic Resistance
  • Quinalone
Characteristics
Tn6010 is a 5.1-kb composite transposon, found on plasmid pOLA52 from E. coli. It contains oqxAB cassettes (encoding a tri-partite resistance-nodulation-division (RND) efflux-pump), which was flanked by two IS26 elements.
References

Norman et al., (2008) Nucleotide sequence of pOLA52: A conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux. Plasmid 60:59-74. DOI: 10.1016/j.plasmid.2008.03.003

Accession number
Contact
ansm@ssi.dk
Tn6011
Mr Anders Norman
University of Copenhagen
  • Virulence Determinants
  • Biofilm formation
Characteristics
Tn6011 is a 5.6-kb composite transposon, found on plasmid pOLA52 from E. coli. It contains mrkABCDF cassette (encoding proteins for the formation of type 3 fimbriae-enhances conjugation and biofilm formation), which was flanked by two IS1 elements.
References

Norman et al., (2008) Nucleotide sequence of pOLA52: A conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux. Plasmid 60:59-74. DOI: 10.1016/j.plasmid.2008.03.003

Accession number
Contact
ansm@ssi.dk
Tn6012
Dr Teruyo Ito
Juntendo University
Characteristics
Tn6012 is a 13.3-kb putative conjugative transposon from Staphylococcus aureus. It carried genes encoding integrase, truncated transposase, an FtsK/SpoIIIE family protein, relaxase and six ORFs that were homologous to ORFs of conjugative transposons Tn916 and Tn5801.
References

Han X, Ito T, Takeuchi F, et al. Identification of a Novel Variant of Staphylococcal Cassette Chromosome mec, Type II.5, and Its Truncated Form by Insertion of Putative Conjugative Transposon Tn6012 . Antimicrobial Agents and Chemotherapy. 2009;53(6):2616-2619. DOI: 10.1128/AAC.00772-08.

Accession number
Contact
teruybac@med.juntendo.ac.jp
Tn6013
Dr D. Ashley Robinson
New York Medical College
  • Antibiotic Resistance
  • Penicillin
Characteristics
Integrative conjugative element from Staphylococcus aureus, designated ICE6013. It is 13.4-kb in length and is predicted to encode 15 ORFs, including an IS30-like DDE transposase in place of a Tyr/Ser recombinase and homologs of gram-positive bacterial conjugation components. ICE6013 can also carry Tn552, which encodes penicillin resistance.
References

Smyth DS, Robinson DA. Integrative and Sequence Characteristics of a Novel Genetic Element, ICE6013, in Staphylococcus aureus  . Journal of Bacteriology. 2009;191(19):5964-5975. DOI:10.1128/JB.00352-09

Accession number
Contact
ashley_robinson@nymc.edu
Tn6014
Miss Lisbeth Elvira de Vries
National Food Institute, DTU
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6014 is a Tn5801-like transposon shown to transfer horizontally from one S. aureus into the S. aureus recipient RN4220F. It contains several ORFs, which includes tetracycline resistance gene tet(M).
References

de Vries, L. E., et al. (2009). "Diversity of the tetracycline resistance gene tet(M) and identification of Tn916- and Tn5801-like (Tn6014) transposons in Staphylococcus aureus from humans and animals." Journal of Antimicrobial Chemotherapy 64(3): 490-500. DOI: 10.1093/jac/dkp214

Accession number
Contact
ledv@life.ku.dk
Tn6015
Dr Richard Eaton
Agricultural Research Service, USDA
Contact
reaton@srrc.ars.usda.gov
Tn6016
Prof Paul Roy
Université Laval
  • Antibiotic Resistance
  • Carbapenem
  • Gentamicin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6016 is an 8.8-kb Tn402-like integron, found on plasmid pOZ176 in Pseudomonas aeruginosa 96 (PA96). It contains class 1 integron, which carried three gene cassette: aacA4, blaIMP-9 and aacA4, encoding resistance to aminoglycosides and carbapenems. It also contains tni operon and mercury resistance operon containing the merRTPFA genes.
References

Xiong J, Alexander DC, Ma JH, et al. Complete Sequence of pOZ176, a 500-Kilobase IncP-2 Plasmid Encoding IMP-9-Mediated Carbapenem Resistance, from Outbreak Isolate Pseudomonas aeruginosa 96. Antimicrobial Agents and Chemotherapy. 2013;57(8):3775-3782. DOI: 10.1128/AAC.00423-13.

Accession number
Contact
paul.roy@crchul.ulaval.ca
Tn6017
Prof Paul Roy
Université Laval
  • Antibiotic Resistance
  • Carbapenem
  • Gentamicin
  • Antispetic Resistance
  • Quaternary ammonium compound
Characteristics
Tn6017 is a Tn402/503-like integron, which was found inserted into the res II site of Tn1722 on plasmid pOZ172 in Citrobacter freundii B38. It contains tni module (tniR-tniQ-tniB-tniA) and a class 1 integron, which carried 4 gene cassettes: blaIMP-4, qacG, aacA4 and aphA15.
References

Xiong J, Déraspe M, Iqbal N, et al. Genome and Plasmid Analysis of blaIMP-4-Carrying Citrobacter freundii B38. Antimicrobial Agents and Chemotherapy. 2016;60(11):6719-6725. DOI: 10.1128/AAC.00588-16.

Accession number
Contact
paul.roy@crchul.ulaval.ca
Tn6018
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Cadmium Resistance
  • Zinc resistance
Characteristics
Tn6018 is a 3.4-kb transposon found in Acinetobacter baumannii strain 3208. It carries cadR-cadA genes, which were fully responsible for cadmium resistance and partially for zinc resistance.
References

Post V, Hall RM. AbaR5, a Large Multiple-Antibiotic Resistance Region Found in Acinetobacter baumannii  . Antimicrobial Agents and Chemotherapy. 2009;53(6):2667-2671. DOI: 10.1128/AAC.01407-08.

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6019
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Arsenate resistance
Characteristics
Backbone of AbaR-type genomic islands in Acinetobacter baumannii. Putative transposition genes related to tniA and tniB of Tn402. Contains genes for arsenate resistance (arsHBRC), a sulphate permease (sup) and universal stress protein (uspA). In AbaR3 type resistance islands, Tn6019 is interrupted by a large insertion containing antibiotic resistance genes and flanked by copies of Tn6018.
References

Post et al., (2010) Evolution of AbaR-type genomic resistance islands in multiply antibiotic-resistant Acinetobacter baumannii. J Antimicrob Chemother. 65; 1162-1170. DOI: 10.1093/jac/dkq095

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6020
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn6020 is a 3-kb composite transposon, found in Acinetobacter baumannii strain 3208. It contained aphA1b gene flanked by directly oriented IS26 elements.
References

Post V, Hall RM. AbaR5, a Large Multiple-Antibiotic Resistance Region Found in Acinetobacter baumannii  . Antimicrobial Agents and Chemotherapy. 2009;53(6):2667-2671. DOI: 10.1128/AAC.01407-08.

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6021
Prof Ruth Hall
The University of Sydney
Characteristics
Tn6021 is a 13.1-kb transposon in comM of Acinetobacter baumannii ATCC17978. Contains ISAba11 in orf1. Related to Tn6019.
References

V.P. Post, P.A. White and R.M. Hall (2010) Evolution of AbaR-type genomic resistance islands in multiply antibiotic-resistant Acinetobacter baumannii. J. Antimicrob. Chemother. 65: 1162-1170 DOI: 10.1093/jac/dkq095

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6022
Prof Ruth Hall
The University of Sydney
Characteristics
Tn6022 is a 12-kb transposon forming the backbone of AbaR4 in Acinetobacter baumannii. Closely related to Tn6021 lacking ISAba11.
References

Hamidian, M. and R. M. Hall (2011). "AbaR4 replaces AbaR3 in a carbapenem-resistant Acinetobacter baumannii isolate belonging to global clone 1 from an Australian hospital." J Antimicrob Chemother 66(11): 2484-2491. DOI: 10.1093/jac/dkr356

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6023
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn6023 is a 2.6 kb composite transposon, found in plasmid pSRC125 from a multiply antibiotic-resistant Salmonella enterica serovar Typhimurium isolate of bovine origin. It comprised of the aphA1b gene flanked by inversely oriented IS26
References

Cain, A. K. and R. M. Hall (2011). "Transposon Tn5393e carrying the aphA1-containing transposon Tn6023 upstream of strAB does not confer resistance to streptomycin." Microb Drug Resist 17(3): 389-394. DOI: 10.1089/mdr.2011.0037

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6024
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Copper Resistance
  • Silver resistance
Characteristics
32.4 kb transposon found in carrying determinants of resistance to copper and silver ions. Found in IncHI2 plasmid R478 (bases 114,733 - 147,146) from Serratia marcescens. Related to Tn7.
References

A.K. Cain and R.M. Hall (2011) A.K. Cain and R.M. Hall (2011) Unpublished

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6025
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Sulphonamide
  • Trimethoprim
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6025 is a 13.3-kb transposon (related to Tn1696 containing mercury resistance operon), found in plasmid pSRC125 in Salmonella enterica Serovar Typhimurium. It contained an In4 type class 1 integron with a dfrA5 gene cassette (conferring trimethoprim resistance) and a sul1 gene (sulfonamide resistance).
References

A.K. Cain, X. Liu, S.P. Djordjevic and R.M. Hall, (2010). "Transposons related to Tn1696 in IncHI2 plasmids in multiply antibiotic resistant Salmonella enterica serovar Typhimurium from Australian animals." Microb Drug Resist 16(3): 197-202. DOI: 10.1089/mdr.2010.0042

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6026
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Ampicillin
  • Kanamycin
  • Neomycin
  • Streptomycin
  • Sulphonamide
  • Trimethoprim
Characteristics
Tn6026 is a 24.3-kb transposon (related to Tn1696), found in plasmid pSRC26 from Salmonella enterica Serovar Typhimurium. It contained an In4 type class 1 integron with a dfrA5 gene cassette, sul1 gene, and the insertion of Tn6029 (containing sul2, strAB, and blaTEM-1 genes) and Tn4352 (containing aphA1 gene) in IS6100.
References

A.K. Cain, X. Liu, S.P. Djordjevic and R.M. Hall, (2010). "Transposons related to Tn1696 in IncHI2 plasmids in multiply antibiotic resistant Salmonella enterica serovar Typhimurium from Australian animals." Microb Drug Resist 16(3): 197-202. DOI: 10.1089/mdr.2010.0042

Accession number
Contact
ruth.hall@sydney.edu.au

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