Tn registry

Displaying 261 - 280 of 907
Tn5252
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn5252 is a 47.5 kb streptococcal conjugative transposon carrying a chloramphenicol resistrance determinant. The Tn5252 is actually the sequence beyond Tn5251 within Tn5253.
References

Ayoubi, P., Kilic, A. O., & Vijayakumar, M. N. (1991). Tn5253, the pneumococcal omega (cat tet) BM6001 element, is a composite structure of two conjugative transposons, Tn5251 and Tn5252. Journal of Bacteriology,173(5), 1617-1622. DOI: 10.1128/jb.173.5.1617-1622.1991

Vijayakumar, M. N., & Ayalew, S. A. H. L. U. (1993). Nucleotide sequence analysis of the termini and chromosomal locus involved in site-specific integration of the streptococcal conjugative transposon Tn5252. Journal of Bacteriology175(9), 2713-2719. DOI: 10.1128/jb.175.9.2713-2719.1993

Kilic, A. O., Vijayakumar, M. N., & Al-Khaldi, S. F. (1994). Identification and nucleotide sequence analysis of a transfer-related region in the streptococcal conjugative transposon Tn5252. Journal of Bacteriology176(16), 5145-5150. DOI: 10.1128/jb.176.16.5145-5150.1994

 

 

 

Tn5253
  • Antibiotic Resistance
  • Chloramphenicol
  • Tetracycline
Characteristics
Tn5253 is a 64.52 kb conjugative transposon of Streptococcus pneumoniae carrying the cat and tet(M) genes. It contains 79 open reading frames. Two distinct genetic elements were found integrated into Tn5253: Tn5251 (18.03 kb) and Ωcat(pC194) (7.6 kb). The Tn5253 was originally detected in the chromosome of Streptococcus pneumoniae BM6001.
References

Ayoubi, P., Kilic, A. O., & Vijayakumar, M. N. (1991). Tn5253, the pneumococcal omega (cat tet) BM6001 element, is a composite structure of two conjugative transposons, Tn5251 and Tn5252. Journal of Bacteriology,173(5), 1617-1622. DOI: 10.1128/jb.173.5.1617-1622.1991

Iannelli, F., Santoro, F., Oggioni, M. R., & Pozzi, G. (2013). Nucleotide sequence analysis of integrative conjugative element Tn5253 of Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy, AAC-01764. DOI: 10.1128/AAC.01764-13

 

Accession number
Tn5271
Characteristics
Tn5271 is a 17 kb transposon located the plasmid or chromosome of Alcaligenes sp. strain BR60. This tarnsposon carries gene(s) that can degrade 3- and 4-chlorobenzoate.
References

Nakatsu, C., Ng, J., Singh, R., Straus, N., & Wyndham, C. (1991). Chlorobenzoate catabolic transposon Tn5271 is a composite class I element with flanking class II insertion sequences. Proceedings of the National Academy of Sciences88(19), 8312-8316. PMCID: PMC52498

Tn5276
Characteristics
Tn5276 is a 70 kb chromosomally located conjugative transposon found in Lactococcus lactis. It confers resistance to nisin, a lanthionine-containing peptide with antimicrobial activity, and helps in utilization of sucrose via a phosphotransferase system.
References

Rauch, P. J., & De Vos, W. M. (1992). Characterization of the novel nisin-sucrose conjugative transposon Tn5276 and its insertion in Lactococcus lactis. Journal of Bacteriology174(4), 1280-1287. DOI: 10.1128/jb.174.4.1280-1287.1992. PMCID: PMC206422

Tn5301
Characteristics
Tn5301 is a 70 kb chromosomally-located transposon that shares the features with Tn916 family of conjugative transposons. It carries the gene clusters for biosynthesis of nisin, a lactococcal peptide antibiotic. It also carries genes for sucrose catabolism.
References

Horn, N., Swindell, S., Dodd, H. and Gasson, M., 1991. Nisin biosynthesis genes are encoded by a novel conjugative transposon. Molecular and General Genetics MGG228(1), pp.129-135. DOI: 10.1007/BF00282457

Tn5306
Characteristics
Tn5306 is a sucrose-nisin transposon that belongs to Tn916 family of conjugative transposon. It was originally found to be located in the chromosome of Lactococcus lactis K1-23.
References

Thompson, J., Sackett, D.L. and Donkersloot, J.A., 1991. Purification and properties of fructokinase I from Lactococcus lactis. Localization of scrK on the sucrose-nisin transposon Tn5306. Journal of Biological Chemistry266(33), pp.22626-22633. PMID: 1658003

Tn5381
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Both the Tn5381 and Tn5383 are 19 kb conjugative transposons related to Tn916. They were originally detected in two different strains of multidrug resistant Enterococcus faecalis. They confer resistance to tetracycline and minocycline via a tetM gene.
References

Rice, L. B., Marshall, S. H., & Carias, L. L. (1992). Tn5381, a conjugative transposon identifiable as a circular form in Enterococcus faecalis. Journal of bacteriology174(22), 7308-7315. PMCID: PMC207425

Tn5382
Characteristics
Tn5382 is a 27 kb transposon encoding VanB-type glycopeptide resistance in Enterococcus faecium.
References

Carias, L. L., Rudin, S. D., Donskey, C. J., & Rice, L. B. (1998). Genetic linkage and cotransfer of a novel, vanB-containing transposon (Tn5382) and a low-affinity penicillin-binding protein 5 gene in a clinical vancomycin-resistant Enterococcus faecium isolate. Journal of Bacteriology,180(17), 4426-4434. PMCID: PMC107451

Tn5383
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Both the Tn5381 and Tn5383 are 19 kb conjugative transposons related to Tn916. They were originally detected in two different strains of multidrug resistant Enterococcus faecalis. They confer resistance to tetracycline and minocycline via a tetM gene.
References

Rice, L. B., Marshall, S. H., & Carias, L. L. (1992). Tn5381, a conjugative transposon identifiable as a circular form in Enterococcus faecalis. Journal of bacteriology174(22), 7308-7315. PMCID: PMC207425

Tn5384
  • Antibiotic Resistance
  • Erythromycin
  • Gentamicin
Characteristics
Tn5384 is a 26 kb erythromycin-gentamicin resistant composite transposon originally detected in Enterococcus faecalis CH116.
References

Rice, L. B., Carias, L. L., & Marshall, S. H. (1995). Tn5384, a composite enterococcal mobile element conferring resistance to erythromycin and gentamicin whose ends are directly repeated copies of IS256. Antimicrobial Agents and Chemotherapy39(5), 1147-1153. PMCID: PMC162698

Tn5385
  • Antibiotic Resistance
  • Erythromycin
  • Gentamicin
  • Penicillin
  • Streptomycin
  • Tetracycline
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn5385 is a 65 kb multidrug resistant composite transposon found to be located in the chromosomes of clinical strains of Enterococcus faecalis ( E. faecalis CH19 and E. faecalis CH116). It confers resistance to erythromycin, gentamicin, mercuric chloride, streptomycin, tetracycline-minocycline, and penicillin via beta-lactamase production. .
References

Rice, L. B., & Carias, L. L. (1998). Transfer of Tn5385, a composite, multiresistance chromosomal element from Enterococcus faecalis. Journal of Bacteriology180(3), 714-721. PMCID: PMC106943

Tn5386
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn5386 is 29 kb ampicillin resistant transposon belong to the family of Tn916. It was originally detected in Enterococcus faecium D344R. It was also found to carry an operon with significant similarities to lantibiotic immunity genes.
References

Rice, L. B., Carias, L. L., Marshall, S., Rudin, S. D., & Hutton-Thomas, R. (2005). Tn5386, a novel Tn916-like mobile element in Enterococcus faecium D344R that interacts with Tn916 to yield a large genomic deletion. Journal of Bacteriology187(19), 6668-6677. PMCID: PMC1251567 DOI: 10.1128/JB.187.19.6668-6677.2005

Rice, L. B., Carias, L. L., Marshall, S. H., Hutton-Thomas, R., & Rudin, S. (2007). Characterization of Tn5386, a Tn916-related mobile element. Plasmid58(1), 61-67. DOI: 10.1016/j.plasmid.2007.01.002

Accession number
Tn5393
Characteristics
Tn5393 is a 6.7 kb transposon which confers resistance to streptomycin via two genes, strA and strB. The Tn5393 was originally found to be located on plasmid pEa34 from streptomycin-resistant strain CA11 of Erwinia amylovora.
References

Chiou, C. S., & Jones, A. L. (1993). Nucleotide sequence analysis of a transposon (Tn5393) carrying streptomycin resistance genes in Erwinia amylovora and other gram-negative bacteria. Journal of Bacteriology175(3), 732-740. PMCID: PMC196212

Accession number
Tn5394
Characteristics
Tn5394 is a 6.33 kb transposon detected on plasmid, pEP36 isolated from Erwinia pyrifoliae strain Ep1/96.
References

McGhee, G. C., Schnabel, E. L., Maxson-Stein, K., Jones, B., Stromberg, V. K., Lacy, G. H., & Jones, A. L. (2002). Relatedness of chromosomal and plasmid DNAs of Erwinia pyrifoliae and Erwinia amylovora. Applied and Environmental Microbiology68(12), 6182-6192. DOI: 10.1128/AEM.68.12.6182-6192.2002

Accession number
Tn5396
Characteristics
Tn5396 is a transposon related to Tn3 family of transposons. It was detected on the plasmid, pEC22 from E.coli.
References

Elhai, J., Cai, Y., & Wolk, C. P. (1994). Conduction of pEC22, a plasmid coding for MR. EcoT22I, mediated by a resident Tn3-like transposon, Tn5396. Journal of Bacteriology176(16), 5059-5067. PMCID: PMC196345

Tn5397
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn5397 is a 21-kb conjugative tranposon, originally isolated from Clostridium difficile. It is very closely related to Tn916, but the transposition of Tn5397 is dependent on the large serine recombinase TndX, not tyrosine recombinase (Int) and Xis like Tn916. It contained 21 ORFs, including tet(M) and a disruption in orf14 by a group II intron.
References

Wang H, Smith MCM, Mullany P. The Conjugative Transposon Tn5397 Has a Strong Preference for Integration into Its Clostridium difficile Target Site. Journal of Bacteriology. 2006;188(13):4871-4878. DOI: 10.1128/JB.00210-06.

Roberts, A. P., et al. (2001). "Comparison of Tn5397 from Clostridium difficile, Tn916 from Enterococcus faecalis and the CW459tet(M) element from Clostridium perfringens shows that they have similar conjugation regions but different insertion and excision modules." Microbiology 147(Pt 5): 1243-1251. DOI: 10.1099/00221287-147-5-1243

Mullany, P., et al. (1996). "A group II intron in a conjugative transposon from the gram-positive bacterium, Clostridium difficile." Gene 174(1): 145-150. DOI: 10.1016/0378-1119(96)00511-2

Accession number
Tn5401
Characteristics
Tn5401 is a 4.8-kb Tn3-like transposon, isolated from a sporulation-deficient variant of Bacillus thuringiensis subsp. morrisoni EG2158. It contains ORF2, ORF1, site-specific recombinase (tnpI), and transposase (tnpA) genes.
References

Baum, J. A. (1994). Tn5401, a new class II transposable element from Bacillus thuringiensis. Journal of Bacteriology176(10), 2835–2845. DOI: 10.1128/jb.176.10.2835-2845.1994

Accession number
Tn5403
Characteristics
Tn5403 is a 3.6-kb Tn3-like transposon, isolated from Klebsiella pneumoniae. It contains tnpA and tnpR genes, providing a helper function in the mobilisation of nonconjugative plasmids.
References

Rinkel M, Hubert JC, Roux B & Lett MC (1994) Identification of a new transposon Tn5403 in a Klebsiella pneumoniae strain isolated from a polluted aquatic environment. Current microbiology 29: 249-254. DOI: 10.1007/BF01577436

Accession number
Tn5404
  • Antibiotic Resistance
  • Kanamycin
  • Streptomycin
Characteristics
Tn5404 is a16-kb transposon, related to Tn552, which is found on plasmid pIP1066 from a methicillin-resistant Staphylococcus aureus strain. It composes of composite transposon Tn5405 (containing IS1181, aphA-3 and aadE resistance genes, which are flanked by IS1182 elements) and genes encoding proteins involved in its transposition.
References

Derbise A, Dyke KG & el Solh N (1995) Rearrangements in the staphylococcal beta-lactamase-encoding plasmid, pIP1066, including a DNA inversion that generates two alternative transposons. Molecular microbiology 17: 769-779. DOI: 10.1111/j.1365-2958.1995.mmi_17040769.x 

Accession number
Tn5405
  • Antibiotic Resistance
  • Kanamycin
  • Neomycin
  • Streptomycin
Characteristics
Tn5405 is a 12-kb composite transposon found as a part of another transposon Tn5404. It contains two aminoglycosides resistance genes, aphA-3 and aadE, which are flanked by inverted repeats of IS1182.
References

Derbise A, de Cespedes G & el Solh N (1997) Nucleotide sequence of the Staphylococcus aureus transposon, Tn5405, carrying aminoglycosides resistance genes. Journal of basic microbiology 37: 379-384. DOI: 10.1002/jobm.3620370511

Accession number

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