The Transposon Registry

Displaying 201 - 220 of 2138
Tn4399
Characteristics
Tn4399 is a 9.6-kb conjugal transposon from Bacteroides fragilis. It contains a 2.8-kb mobilisation cassette (mocA and mocB gene).
References

Murphy, C. G., & Malamy, M. H. (1993). Characterization of a “mobilization cassette” in transposon Tn4399 from Bacteroides fragilis. Journal of Bacteriology, 175(18), 5814–5823. DOI: 10.1128/jb.175.18.5814-5823.1993

Hecht, DW, et al. (1989). Characterization of the termini and transposition products of Tn4399, a conjugal mobilizing transposon of Bacteroides fragilis. Proceedings of the National Academy of Sciences of the United States of America, 86(14), 5340–5344. DOI: 10.1128/jb.171.7.3603-3608.1989

Accession number
Tn4400
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn4400 is a composite transposon isolated from Bacteroides fragilis. It is almost identical to Tn4351, by containing tetX and ermF resistance genes, flanked by direct repeats of IS4400. There is a 4-bp different at the upstream region of tetX between both transposon.
References

Speer, B. S., Bedzyk, L., & Salyers, A. A. (1991). Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase. Journal of Bacteriology, 173(1), 176–183. DOI: 10.1128/jb.173.1.176-183.1991

Robillard, N. J., Tally, F. P., & Malamy, M. H. (1985). Tn4400, a compound transposon isolated from Bacteroides fragilis, functions in Escherichia coli. Journal of Bacteriology, 164(3), 1248–1255. PMID: 2999075

Tn4401
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn4401 is a 10 kb transposon related to Tn3-family from Klebsiella pneumoniae strain Kp512. It carries a blaKPC gene that mediates resistance to carbapenems.
References

Cuzon, G., Naas, T., & Nordmann, P. (2011). Functional characterization of Tn4401, a Tn3-based transposon involved in blaKPC gene mobilization.Antimicrobial Agents and Chemotherapy, 55(11), 5370-5373. DOI: 10.1128/AAC.05202-11

Accession number
Tn4411
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn4411 is a kanamycin resistance transposon. It was detected within plasmid pAV51 of Acinetobacter calcoaceticus.
References

Divers M., Craven, P. L., & Vivian, A. (1985). Molecular analysis of an antibiotic resistance plasmid, pAV5, and its derivative plasmids in Acinetobacter calcoaceticus. Microbiology, 131(12), 3367-3374. DOI: 10.1099/00221287-131-12-3367

Tn4430
Characteristics
Tn4430 is a 4.2 kb transposon originally detected in Bacillus thuringiensis. Tn4430 is closely related to the transposons belonging to the Tn3-family
References

Lereclus, D., Mahillon, J., Menou, G., & Lecadet, M. M. (1986). Identification of Tn4430, a transposon of Bacillus thuringiensis functional in Escherichia coli. Molecular and General Genetics MGG, 204(1), 52-57. DOI: 10.1007/BF00330186

Accession number
Tn4431
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn4431 is an artificial transposon generated by inserting five lux genes into a Tn1721 derivative. It carries a tetracycline resistance determinant.
References

Steinmann, D., Wiggerich, H. G., Klauke, B., Schramm, U., Pühler, A., & Priefer, U. B. (1993). Saturation mutagenesis in Escherichia coli of a cloned Xanthomonas campestris DNA fragment with the lux transposon Tn4431 using the delivery plasmid pDS1, thermosensitive in replication. Applied Microbiology and Biotechnology, 40(2), 356-360. DOI: 10.1007/BF00170392

Tn4451
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn4451 is a 6.33 kb chloramphenicol-resistance transposon detected in plasmid, plP401 of Clostridium perfringens.
References

Abraham, L. J., & Rood, J. I. (1987). Identification of Tn4451 and Tn4452, chloramphenicol resistance transposons from Clostridium perfringens. Journal of Bacteriology, 169(4), 1579-1584. DOI: 10.1128/jb.169.4.1579-1584.1987

Bannam, T. L., Crellin, P. K., & Rood, J. I. (1995). Molecular genetics of the chloramphenicol‐resistance transposon Tn4451 from Clostridium perfringens: the TnpX site‐specific recombinase excises a circular transposon molecule. Molecular Microbiology, 16(3), 535-551. DOI: 10.1111/j.1365-2958.1995.tb02417.x

Accession number
Tn4452
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn4452 is a 6.2 kb transposon which is identical for most of their length to Tn4451 and differed only at its right-hand end.
References

Abraham, L. J., & Rood, J. I. (1987). Identification of Tn4451 and Tn4452, chloramphenicol resistance transposons from Clostridium perfringens. Journal of Bacteriology, 169(4), 1579-1584. DOI:10.1128/jb.169.4.1579-1584.1987

Tn4521
  • Virulence Determinants
  • Toxin production
Characteristics
Tn4521 is a composite transposon found in Escherichia coli. It contains enterotoxin STII gene, flanked by two truncated IS2 elements
References

Hu, S. T. and C. H. Lee (1988). Characterization of the transposon carrying the STII gene of enterotoxigenic Escherichia coli. Mol Gen Genet 214(3): 490-495. DOI: 10.1007/BF00330485

Accession number
Tn4527
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Trimethoprim
Characteristics
Tn4527 is a 19.6-kb composite transposon, related to Tn7. It is isolated from a multiresistant Salmonella typhimurium, and contains genes conferring trimethoprim, spectinomycin, and streptomycin, flanked by direct repeats of IS1 elements.
References

Dumans, A. T., et al. (1989). Tn4527, a Tp Sp/Sm transposon related to Tn7 and flanked by IS1. Plasmid 22(3): 256-259. DOI: 10.1016/0147-619X(89)90009-7

Tn4551
  • Antibiotic Resistance
  • Clindamycin
  • Streptomycin
Characteristics
Tn4551 is a 7.6 kb composite transposon, located on plasmid pBI136 from Bacteroides fragilis. It contains two IS4351 elements flanking, ermFS and aadS genes. .
References

Smith, C. J., et al. (1992). Activation of a cryptic streptomycin-resistance gene in the Bacteroides erm transposon, Tn4551. Mol Microbiol 6(16): 2287-2297. DOI: 10.1111/j.1365-2958.1992.tb01404.x

Accession number
Tn4555
  • Antibiotic Resistance
  • Cefoxitin
Characteristics
Tn4555 is a 12.1-kb transposon, isolated from Bacteroides vulgatus. It carries genes, encoding an extended spectrum β-lactamase (cfxA), TnpA (tnpA), integrase (int), TnpC (tnpC), excisionase (xis), and mobilization protein (mobA).
References

Bacic, M. K. and C. J. Smith (2005). "Analysis of chromosomal insertion sites for Bacteroides Tn4555 and the role of TnpA." Gene 353(1): 80-88. DOI: 10.1016/j.gene.2005.03.014

Accession number
Tn4556
Characteristics
Tn4556 is a 6.8-kb Tn3-related transposon, isolated from Streptomyces fradiae.
References

Chung, S. T. (1987). Tn4556, a 6.8-kilobase-pair transposable element of Streptomyces fradiae. Journal of Bacteriology, 169(10), 4436–4441. DOI: 10.1128/jb.169.10.4436-4441.1987

Accession number
Tn4560
  • Antibiotic Resistance
  • Viomycin
Characteristics
Tn4560 is an 8.6-kb transposon, derived from Tn4556. It contains tnpA (transposase), tnpR (resolvase) and vph (viomycin phosphotransferase) genes.
References

Bhatt, A., et al. (2002). Transposition of Tn4560 of Streptomyces fradiae in Mycobacterium smegmatis. FEMS Microbiol Lett 206(2): 241-246. DOI: 10.1111/j.1574-6968.2002.tb11016.x

Tn4563
  • Antibiotic Resistance
  • Viomycin
Characteristics
Tn4563 is an 8.6-kb transposon, derived from Tn4556. It contains tnpA (transposase), tnpR (resolvase) and vph (viomycin phosphotransferase) genes.
References

Schauer, A. T., Nelson, A. D., & Daniel, J. B. (1991). Tn4563 transposition in Streptomyces coelicolor and its application to isolation of new morphological mutants. Journal of Bacteriology, 173(16), 5060–5067. DOI: 10.1128/jb.173.16.5060-5067.1991

Tn4651
  • Metabolism
  • Toluene degradation
Characteristics
Tn4651 is a 56-kb transposon, related to Tn3, which is found on plasmid pWW0 from Pseudomonas putida. It contains toluene-degrading (xyl) genes, flanked by direct repeats of IS1246 elements.
References

Genka, H., Nagata, Y., & Tsuda, M. (2002). Site-Specific Recombination System Encoded by Toluene Catabolic Transposon Tn4651. Journal of Bacteriology, 184(17), 4757–4766. DOI: 10.1128/JB.184.17.4757-4766.2002

Tsuda, M., Minegishi, K., & Iino, T. (1989). Toluene transposons Tn4651 and Tn4653 are class II transposons. Journal of Bacteriology, 171(3), 1386–1393. DOI: 10.1128/jb.171.3.1386-1393.1989

Accession number
Tn4652
  • Metabolism
  • Toluene degradation
Characteristics
Tn4652 is a 17-kb transposon, which is a derivative of transposon Tn4651 by a deletion of 39-kb DNA fragment, containing toluene degradation genes.
References

Tsuda, M., Minegishi, K., & Iino, T. (1989). Toluene transposons Tn4651 and Tn4653 are class II transposons. Journal of Bacteriology, 171(3), 1386–1393. DOI: 10.1128/jb.171.3.1386-1393.1989

Tsuda, M. and T. Iino (1987). Genetic analysis of a transposon carrying toluene degrading genes on a TOL plasmid pWW0. Mol Gen Genet 210(2): 270-276. DOI: 10.1007/BF00325693

Accession number
Tn4653
  • Metabolism
  • Toluene degradation
Characteristics
Tn4653 is related to Tn4651 and is also found on plasmid pWW0 from Pseudomonas. It contains Tn4651 (containing toluene degradation xyl gene) with an addition of tnpA and tnpR genes.
References

Tsuda, M., Minegishi, K., & Iino, T. (1989). Toluene transposons Tn4651 and Tn4653 are class II transposons. Journal of Bacteriology, 171(3), 1386–1393. DOI: 10.1128/jb.171.3.1386-1393.1989

Tsuda, M. and T. Iino (1988). "Identification and characterization of Tn4653, a transposon covering the toluene transposon Tn4651 on TOL plasmid pWW0." Mol Gen Genet 213(1): 72-77. DOI: 10.1007/BF00333400

Tn4654
Characteristics
Tn4654 is a derivative of transposon Tn4653 with a deletion of 39-kb DNA fragment, containing toluene degradation genes.
References

Tsuda, M., Minegishi, K., & Iino, T. (1989). Toluene transposons Tn4651 and Tn4653 are class II transposons. Journal of Bacteriology, 171(3), 1386–1393. DOI: 10.1128/jb.171.3.1386-1393.1989

Tn4655
  • Metabolism
  • Naphthalene degradation
Characteristics
Tn4655 is a 39-kb transposon which is found on a self-transmissible plasmid NAH7 from Pseudomonas putida. It carries 33 ORFs, which 23 of them are naphthalene-catabolic (nah) genes.
References

Sota, M., et al. (2006). Genomic and Functional Analysis of the IncP-9 Naphthalene-Catabolic Plasmid NAH7 and Its Transposon Tn4655 Suggests Catabolic Gene Spread by a Tyrosine Recombinase. Journal of Bacteriology, 188(11), 4057–4067. DOI: 10.1128/JB.00185-06

Accession number

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