The Transposon Registry

Displaying 361 - 380 of 2138
Tn6047
Ms Sae Tsubakishita
Juntendo university
Contact
stsubaki@juntendo.ac.jp
Tn6048
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Characteristics
Tn6048 is a 10.4 kb transposon, found in Cupriavidus metallidurans CH34. It contained 12 genes, which 4 of them were for transposon maintenance and mobility. The other eight genes were responding to heavy metal since they were induced by zinc and lead.
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Accession number
Contact
rvhoudto@sckcen.be
Tn6049
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Characteristics
Tn6049 is a 3.5-kb transposon found in Cupriavidus metallidurans CH34. It contained 4 genes: tnmC, gspA (ATPase for type II general secretion pathway), tnmA (transposase) and tnmB (Protein involved in mobility of Tn6049) genes.
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Accession number
Contact
rvhoudto@sckcen.be
Tn6050
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Characteristics
Tn6050 is a 6.8-kb transposon, found in Cupriavidus metallidurans CH34. It carried accessory genes, encoding a transposase, a resolvase, a sulfate permease, a universal stress protein (UspA), and a DksA-like DnaK suppressor protein.
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Accession number
Contact
rvhoudto@sckcen.be
Tn6051
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Characteristics
Tn6051 is a Tn3-related transposon, found in Delftia acidovorans strain SPH-1.
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Contact
rvhoudto@sckcen.be
Tn6052
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Characteristics
Tn6052, also called ISPpu12, is a four-gene transposon (pbrR cdfX pbrC tnpA), found in Burkholderia xenovorans LB400.
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Contact
rvhoudto@sckcen.be
Tn6053
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
References

Van Houdt, R., et al. (2009). "New mobile genetic elements in Cupriavidus metallidurans CH34, their possible roles and occurrence in other bacteria." Antonie van Leeuwenhoek 96(2): 205-226. DOI: 10.1007/s10482-009-9345-4

Contact
rvhoudto@sckcen.be
Tn6054
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Contact
rvhoudto@sckcen.be
Tn6055
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Contact
rvhoudto@sckcen.be
Tn6056
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Contact
rvhoudto@sckcen.be
Tn6057
Dr Rob Van Houdt
Unit for Microbiology, SCK-CEN
Contact
rvhoudto@sckcen.be
Tn6058
Dr Mingoia Marina
Department of Biomedical Sciences
  • Antibiotic Resistance
  • Chloramphenicol
  • Erythromycin
  • Tetracycline
Characteristics
Tn6058 is a 67.8-kb Tn5253-related element from Streptococcus pneumoniae isolate Pn20. It composed of Tn6002 (containing tet(M) and erm(B)) inserted in Tn5252. A large portion (almost 16 kb) of Tn6058, formed largely by cargo genes and including the pC194 plasmid (containing catpC194 gene).
References

Mingoia M, Tili E, Manso E, Varaldo PE, Montanari MP. Heterogeneity of Tn5253-Like Composite Elements in Clinical Streptococcus pneumoniae Isolates. Antimicrobial Agents and Chemotherapy. 2011;55(4):1453-1459. DOI: 10.1128/AAC.01087-10.

Accession number
Contact
m.mingoia@univpm.it
Tn6059
Prof Maria Pia Montanari
Institute of Microbiology and Biomedical
Contact
mp.montanari@univpm.it
Tn6060
Dr Piklu Roy Chowdhury
the i3 institute, Faculty of Science
  • Antibiotic Resistance
  • Carbapenem
  • Chloramphenicol
  • Kanamycin
  • Neomycin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6060 is a 25.4-kb Tn1403-like composite transposon, found in the Pseudomonas aeruginosa strain 171b genome fragment cloned as fosmid 32. It contained two ISPa7 elements flanking two In70.2-like class 1 integrons, which inserted into Tn1403, generating a transposon that collectively includes six resistance cassettes. The large-array integron contained the cassettes aadA1, aphA15, aacA4, and blaVIM1, while the smaller cassette array carried aacC3-cmlA5. The sul1 gene can also be found in a 3' conserved region of both integrons.
References

Chowdhury PR, Merlino J, Labbate M, Cheong EY-L, Gottlieb T, Stokes HW. Tn6060, a Transposon from a Genomic Island in a Pseudomonas aeruginosaClinical Isolate That Includes Two Class 1 Integrons . Antimicrobial Agents and Chemotherapy. 2009;53(12):5294-5296. DOI: 10.1128/AAC.00687-09.

Accession number
Contact
piklu.bhattacharya@uts.edu.au
Tn6061
Mr Sebastien Coyne
Institut Pasteur
  • Antibiotic Resistance
  • Amikacin
  • Ceftazidime
  • Chloramphenicol
  • Ciprofloxacin
  • Gentamicin
  • Rifampicin
  • Sulphonamide
  • Tetracycline
  • Tobramycin
Characteristics
Tn6061 is a 26.6-kb Tn3-like transposon, found in six multiresistant clinical isolates of Pseudomonas aeruginosa. It carried a class 1 integron, which was terminated by an IS6100 element. Ten genes conferring resistance to six drug classes were carried by Tn6061 including, β-lactams (bla VEB-1, bla OXA-10), aminoglycosides [ant( 2′) -Ia, ant( 3′′) -Ia, ant( 4') -IIb], tetracycline [tet(G)], rifampicin (arr-2), chloramphenicol (cmlA5, floR) and sulfonamides (sul1).
References

Coyne, S., et al. (2010). "Acquisition of multidrug resistance transposon Tn6061 and IS6100-mediated large chromosomal inversions in Pseudomonas aeruginosa clinical isolates." Microbiology 156(Pt 5): 1448-1458. DOI: 10.1099/mic.0.033639-0

Accession number
Contact
sebastien.coyne@pasteur.fr
Tn6062
Mr Minh-Duy Phan
The Wellcome Trust Sanger Institute
  • Efflux functions
Characteristics
Tn6062 is a 4.9-kb composite transposon, found in PST6 IncHI1 plasmids from Salmonella enterica serovar Typhi. It contained 4 genes (SPAP0100, SPAP0105, SPAP0106, SPAP0110) flanked by IS1 elements. SPAP0106 encodes a betaine uptake system capable of transporting glycine betaine and proline betaine, which was shown to confer an osmotolerant phenotype (grow in high salt).
References

Holt KE, Phan MD, Baker S, et al. Emergence of a Globally Dominant IncHI1 Plasmid Type Associated with Multiple Drug Resistant Typhoid. Ryan ET, ed. PLoS Neglected Tropical Diseases. 2011;5(7):e1245. doi:10.1371/journal.pntd.0001245.

Accession number
Contact
dp3@sanger.ac.uk
Tn6063
Dr Jaroslaw Krol
University of Idaho
  • Metabolism
  • Chloroaniline degradation
Characteristics
Tn6063 is a 22.4-kb composite transposon, found in IncP-1β Plasmids pWDL7::rfp (an 86.6-kb derivative of plasmid pWDL7 from Comamonas testosteroni strain WDL7). It composed of two IS elements (IS1071 and IS1071a) flanking a region that contains two IS elements (IS21 and IS66) as well as a degradation of chloroaniline (dca) gene cluster (dcaQTA1A2BR).
References

Król JE, Penrod JT, McCaslin H, et al. Role of IncP-1β Plasmids pWDL7::rfpand pNB8c in Chloroaniline Catabolism as Determined by Genomic and Functional Analyses. Applied and Environmental Microbiology. 2012;78(3):828-838. DOI: 10.1128/AEM.07480-11.

Accession number
Contact
jkrol@uidaho.edu
Tn6064
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6065
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6066
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com

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