The Transposon Registry

Displaying 421 - 440 of 2138
Tn6107
Mr Michael Brouwer
UCL Eastman Dental Institute
  • Efflux functions
Characteristics
Tn6107 is a 50.5-kb transposon (CTn5-like element) found in Clostridium difficile strain QCD-23M63. It contained genes encoding putative transcriptional regulators and ABC-transporters in its accessory module.
References

Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E. Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile . Highlander SK, ed. PLoS ONE. 2011;6(8):e23014. DOI: 10.1371/journal.pone.0023014.

Accession number
Contact
m.brouwer@ucl.ac.uk
Tn6108
Dr Jaroslaw Krol
University of Idaho
  • Antibiotic Resistance
  • Ampicillin
  • Kanamycin
  • Streptomycin
  • Sulphonamide
  • Tetracycline
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6108 is a 31-kb composite transposon found in plasmid pSal8934b from Salmonella enterica subsp. enterica serovar strain 8934. It contained two IS1294 element, flanking beta-lactamase gene, and Tn21 transposon [containing aadA, sul1, IS21, tetA-tetR, mercury resistance operon (merREDA), aph gene]. It was found adjacent to and sharing an IS1294 with Tn6109.
References
Krol,J.E., Orfe,L.H., Sota,M., Rogers,L.M., Top,E.M. and Call,D.R. (Unpublished) Hitchhiking as a natural way of spreading antibiotic resistance and virulence genes from Salmonella enterica
Accession number
Contact
jkrol@uidaho.edu
Tn6109
Dr Jaroslaw Krol
University of Idaho
Characteristics
Tn6109 is a 23-kb composite transposon, found in plasmid pSal8934b from Salmonella enterica subsp. enterica serovar strain 8934. It was contained two IS1294 elements, flanking 25 ORFs [encoding transposase and hypothetical proteins]. It was found adjacent to and sharing an IS1294 with Tn6108.
References
Krol,J.E., Orfe,L.H., Sota,M., Rogers,L.M., Top,E.M. and Call,D.R. (Unpublished) Hitchhiking as a natural way of spreading antibiotic resistance and virulence genes from Salmonella enterica
Accession number
Contact
jkrol@uidaho.edu
Tn6110
Mr Michael Brouwer
UCL Eastman Dental Institute
Characteristics
Tn6110 is a 58-kb CTn5-like element found in Clostridium difficile strain QCD-66C26.
References

Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E. Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile. Highlander SK, ed. PLoS ONE. 2011;6(8):e23014. DOI: 10.1371/journal.pone.0023014.

Accession number
Contact
m.brouwer@ucl.ac.uk
Tn6111
Mr Michael Brouwer
UCL Eastman Dental Institute
Characteristics
Tn6111 is a 53.4-kb CTn5-like element found in Clostridium difficile strain QCD-32G58.
References

Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E. Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile . Highlander SK, ed. PLoS ONE. 2011;6(8):e23014. DOI: 10.1371/journal.pone.0023014.

Accession number
Contact
m.brouwer@ucl.ac.uk
Tn6112
Ms Ammara Sajjad
Macquarie University
Characteristics
Tn6112 is a 7.3-kb Tn402-like integron found in Pseudomonas sp. strain 11BF10. It contained integron integrase gene, two gene cassettes (orfB and orf132), a complete tni transposition module (tniRQBA), which were flanked by 25-bp inverted repeats.
References

Sajjad A, Holley MP, Labbate M, Stokes HW, Gillings MR. Preclinical Class 1 Integron with a Complete Tn402-Like Transposition Module . Applied and Environmental Microbiology. 2011;77(1):335-337. DOI: 10.1128/AEM.02142-10.

Accession number
Contact
ammara.sajjad@mq.edu.au
Tn6113
Dr Marek Gniadkowski
National Medicines Institute
  • Antibiotic Resistance
  • Cefotaxime
  • Cefoxitin
  • Ceftazidime
  • Penicillin
  • Efflux functions
Characteristics
Tn6113 is a transposition module consisting of ISEcp1 and a fragment of the Citrobacter freundii-derived chromosomal DNA containing genes blaCMY-12, blc and delta sugE (a part of sugE truncated during the ISEcp1-mediated mobilization). blaCMY-12 is a gene encoding a C. freundii-like AmpC cephalosporinase variant conferring resistance to a majority of beta-lactam antibiotics. Tn6113 was identified in a Proteus mirabilis clinical isolate 27/00 from a Polish hospital
References

D’Andrea MM, Literacka E, Zioga A, et al. Evolution and Spread of a Multidrug-Resistant Proteus mirabilis Clone with Chromosomal AmpC-Type Cephalosporinases in Europe. Antimicrobial Agents and Chemotherapy. 2011;55(6):2735-2742. DOI: 10.1128/AAC.01736-10

Accession number
Contact
gniadkow@cls.edu.pl
Tn6114
Dr Vivi Miriagou
Hellenic Pasteur Institute
  • Antibiotic Resistance
  • Cefotaxime
  • Cefoxitin
  • Ceftazidime
  • Penicillin
  • Efflux functions
Characteristics
Tn6114 is a transposition module consisting of ISEcp1 and a fragment of the Citrobacter freundii-derived chromosomal DNA containing genes blaCMY-36, blc and sugE (efflux transporter). blaCMY-36 is a gene encoding a C. freundii-like AmpC cephalosporinase variant conferring resistance to a majority of beta-lactam antibiotics. Tn6114 was identified in the Klebsiella pneumoniae clinical isolate HP205 from a Greek hospital.
References

D'Andrea MM, Literacka E, Zioga A, et al. Evolution and spread of a multidrug-resistant Proteus mirabilis clone with chromosomal AmpC-type cephalosporinases in Europe. Antimicrob Agents Chemother. 2011;55(6):2735-42. DOI: 10.1128/AAC.01736-10

Accession number
Contact
miriagou@pasteur.gr
Tn6115
Mr Michael Brouwer
UCL Eastman Dental Institute
  • Efflux functions
Characteristics
Tn6115 is a 13.6-kb putative transposon found in Clostridium difficile strain QCD-63Q42. It contained genes, encoding several hypothetical proteins, a serine recombinase, a predicted ABC transporter (ORFs 7732 and 7737), a protein containing a predicted virulence-associated E domain (ORF 7777) and a two-component system.
References

Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E. Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile . Highlander SK, ed. PLoS ONE. 2011;6(8):e23014. DOI: 10.1371/journal.pone.0023014.

Contact
m.brouwer@ucl.ac.uk
Tn6116
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6117
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6118
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6119
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6120
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6121
Mr Michael Brouwer
UCL Eastman Dental Institute
Contact
m.brouwer@ucl.ac.uk
Tn6122
Dr Lukasz Dziewit
University of Warsaw
Characteristics
Tn6122 is a 3.8-kb Tn3-family transposon, which was captured in Paracoccus halophilus strain JCM 14014 by using the trap plasmid pMEC1. It contained identical 39-bp IRs, two ORFs (tnpA and tnpR), and an AT-rich putative recombination site (res).
References

Dziewit L, Baj J, Szuplewska M, et al. Insights into the Transposable Mobilome of Paracoccus spp. (Alphaproteobacteria). Van Melderen L, ed. PLoS ONE. 2012;7(2):e32277. DOI: 10.1371/journal.pone.0032277.

Accession number
Contact
ldziewit@biol.uw.edu.pl
Tn6123
Dr Lukasz Dziewit
University of Warsaw
Contact
ldziewit@biol.uw.edu.pl
Tn6124
Dr Lukasz Dziewit
University of Warsaw
Contact
ldziewit@biol.uw.edu.pl
Tn6125
Dr Jaroslaw Krol
University of Idaho
  • Metabolism
  • Chloroaniline degradation
Characteristics
Tn6125 is a 32.8-kb composite transposon, found in plasmid pC1-1 from Delftia acidovorans strain CA28. It contained two IS1071 elements flanking genes for chloroaniline degradation (dcaQTA1A2BR), and two IS21 elements.
References
Krol,J.E., Rogers,L.M., Sen,D. and Top,E.M. (Unpublished) Family of IncP-1 plasmids involved in chloroaniline degradation
Accession number
Contact
jkrol@uidaho.edu
Tn6126
Dr Jaroslaw Krol
University of Idaho
  • Metabolism
  • Chloroaniline degradation
Characteristics
Tn6126 is a 35.9-kb composite transposon, found in plasmid pLME1 from Delftia acidovorans strain LME1. It contained two IS1071 elements flanking two IS66 elements, two IS21 elements and genes for chloroaniline degradation (dcaQTA1A2BR).
References

Boon N, Goris J, De Vos P, Verstraete W, Top EM. Genetic Diversity among 3-Chloroaniline- and Aniline-Degrading  Strains of the Comamonadaceae. Applied and Environmental Microbiology. 2001;67(3):1107-1115. DOI: 10.1128/AEM.67.3.1107-1115.2001.

Accession number
Contact
jkrol@uidaho.edu

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