The Transposon Registry

Displaying 481 - 500 of 2138
Tn6167
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Carbapenem
  • Streptomycin
  • Sulphonamide
  • Tetracycline
Characteristics
Tn6167 is a 33-kb transposon in comM of Acinetobacter baumannii GC2 strain A91. It carried Tn6022Δ1, which was interrupted by ISAba17, Tn2006 [carrying blaOXA-23 flanked by two ISAba1], the sul2 sulphonamide resistance gene, the tet(B) tetracycline resistance determinant and the strA and strB streptomycin resistance genes.
References

Nigro, S. J. and R. M. Hall (2012). "Tn6167, an antibiotic resistance island in an Australian carbapenem-resistant Acinetobacter baumannii GC2, ST92 isolate." Journal of Antimicrobial Chemotherapy 67(6): 1342-1346. DOI: 10.1093/jac/dks037

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6168
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Cefotaxime
  • Ceftazidime
Characteristics
Tn6168 is a 5.5-kb composite transposon, found in Acinetobacter baumannii strain A85 clone GC1. It carried ampC, flanked by ISAba1.
References

Hamidian, M. and R. M. Hall (2014). "Tn6168, a transposon carrying an ISAba1-activated ampC gene and conferring cephalosporin resistance in Acinetobacter baumannii." Journal of Antimicrobial Chemotherapy 69(1): 77-80. DOI: 10.1093/jac/dkt312

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6169
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6170
Prof Ruth Hall
The University of Sydney
Characteristics
Tn6170 is an 18.8-kb Tn7-family transposon, found in plasmid pNDM-1_Dok01, pNDM-KN, pNDM10505 and pNDM102337. It encoded hsdR operon and three transposition genes [tnsABC related to Tn7].
References

Harmer, C. J. and R. M. Hall (2014). "pRMH760, a precursor of A/C(2) plasmids carrying blaCMY and blaNDM genes." Microb Drug Resist 20(5): 416-423. DOI: 10.1089/mdr.2014.0012 

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6171
Prof Ruth Hall
The University of Sydney
  • Metabolism
  • Siderophore synthesis
Characteristics
Tn6171 is a 49.9-kb transposon, found in Acinetobacter baumannii Strain D36. It carried a potential siderophore synthesis gene cluster and genes for transposition [related to those of Tn7].
References

Hamidian M, Hawkey J, Holt KE, Hall RM. Genome Sequence of Acinetobacter baumannii Strain D36, an Antibiotic-Resistant Isolate from Lineage 2 of Global Clone 1. Genome Announcements. 2015;3(6):e01478-15. DOI: 10.1128/genomeA.01478-15.

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6172
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6172 an 11.7-kb class III transposon, found in plasmid pD4 and pA297-3 of Acinetobacter baumannii strain D4 (genotype ST25) and A297 (RUH875), respectively. It carried genes for transposition (tniCbAbBb), ISAba1, sul2 (sulphonamide resistance), CR2 mobile element and strB-strA (streptomycin resistance) genes.
References

Hamidian, M., et al. (2016). "A large conjugative Acinetobacter baumannii plasmid carrying the sul2 sulphonamide and strAB streptomycin resistance genes." Plasmid 87-88: 43-50. DOI: 10.1016/j.plasmid.2016.09.001

Hamidian, M. and R. M. Hall (2016). "The resistance gene complement of D4, a multiply antibiotic-resistant ST25 Acinetobacter baumannii isolate, resides in two genomic islands and a plasmid." J Antimicrob Chemother 71(6): 1730-1732. DOI: 10.1093/jac/dkw041

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6173
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6174
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6175
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6176
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Copper Resistance
  • Virulence Determinants
  • Hemolysin production
Characteristics
Tn6176 is a 3.4-kb transposon, found in plasmid pC13-2 from Acinetobacter baumannii strain C13 clone G2. It contained genes encoding proteins for transposition (tniABDE), copper resistance and hemolysin D.
References
Nigro,S.J. and Hall,R.M. (Unpublished) Loss and gain of aminoglycoside resistance in GC2 Acinetobacter baumannii in Australia via modification of genomic resistance islands and acquisition of plasmids
Accession number
Contact
ruth.hall@sydney.edu.au
Tn6177
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Copper Resistance
Characteristics
Tn6177 is a 35.6-kb transposon, found in plasmid pS21-2 from Acinetobacter baumannii strain SGH9601 (DR21208). It contained genes encoding proteins for transposition (tniCABDE) and copper resistance.
References
Blackwell,G.A. and Hall,R.M. (Unpublished) Compatibility and mobilisation of RepAci1 and RepAci2 plasmids carrying antibiotic resistance genes
Accession number
Contact
ruth.hall@sydney.edu.au
Tn6178
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Kanamycin
  • Neomycin
  • Efflux functions
Characteristics
Tn6178 is a 4.6-kb composite transposon found in Acinetobacter Genomic Island 1 (AGI1) of Acinetobacter baumannii strain D4. It contained two IS26 elements, flanking aphA1b and glutamine ABC transporter genes.
References
Hamidian,M. and Hall,R.M. (Unpublished) Acinetobacter baumannii genomic island 1 (AGI1) a novel antibiotic resistance island found in ST25 A. baumannii
Accession number
Contact
ruth.hall@sydney.edu.au
Tn6179
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Kanamycin
  • Neomycin
Characteristics
Tn6179 is a 2.7-kb composite transposon, found adjacent to and sharing an IS26 with Tn6180 in Acinetobacter baumannii strain SGH0701 genomic resistance island AbGRI3. It contained aphA1b gene, flanked by two IS26 elements.
References

Blackwell GA, Holt KE, Bentley SD, Hsu LY, Hall RM. Variants of AbGRI3 carrying the armA gene in extensively antibiotic-resistant Acinetobacter baumannii from Singapore. Journal of Antimicrobial Chemotherapy. 2017;72(4):1031-1039. DOI: 10.1093/jac/dkw542.

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6180
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Chloramphenicol
  • Gentamicin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Tobramycin
Characteristics
Tn6180 is a 19-kb IS26-bounded transposon, found in Acinetobacter baumannii strain SGH0701 genomic resistance island AbGRI3. It was similar to Tn1548, but had an insertion of ISAba24. The class 1 integron [containing sul1 gene in 3'CS] on Tn6180 was also different by having a different set of cassettes aadA1-catB8-aacA4 and a 216 bp-deletion in integron integrase gene.
References

Blackwell GA, Holt KE, Bentley SD, Hsu LY, Hall RM. Variants of AbGRI3 carrying the armA gene in extensively antibiotic-resistant Acinetobacter baumannii from Singapore. Journal of Antimicrobial Chemotherapy. 2017;72(4):1031-1039. DOI: 10.1093/jac/dkw542.

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6181
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Ampicillin
  • Streptothricin
  • Trimethoprim
Characteristics
Tn6181 is a 19.4-kb transposon, found in Escherichia coli strain 10.1-R1. It contained dfrA1, sat2, Tn2 transposon [containing tnpA, tnpR, and blaTEM] and genes for transposition [tnsABCDE].
References
Moran,R.A. and Hall,R.M. (Unpublished) Commensal Escherichia coli ST14 10.1-R1, Tn6181 complete sequence
Accession number
Contact
ruth.hall@sydney.edu.au
Tn6182
Prof Ruth Hall
The University of Sydney
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6182 is a 11.5-kb class II transposon, carried a mercuric ion resistance operon (merACPTR). It was found in plasmid pIP40a from Pseudomonas aeruginosa, where it was inserted in the intergenic region downstream of rhs1 in pIP40a.
References

Harmer, C. J., et al. (2017). "pIP40a, a type 1 IncC plasmid from 1969 carries the integrative element GIsul2 and a novel class II mercury resistance transposon." Plasmid 92: 17-25. DOI: 10.1016/j.plasmid.2017.05.004

Accession number
Contact
ruth.hall@sydney.edu.au
Tn6183
Prof Ruth Hall
The University of Sydney
  • Antibiotic Resistance
  • Erythromycin
  • Streptomycin
  • Tetracycline
Characteristics
Tn6183 is a 25.8-kb transposon, found in plasmid pD46-4 from Acinetobacter baumannii strain D46. It contained ISAba1, tetA(B), tetR(B), three IS26 elements [two of them were flanking erythromycin resistance genes (mphE and msrE genes)], strA and strB genes conferring streptomycin resistance.
References
Nigro,S.J. and Hall,R.M. (Unpublished) A large plasmid, pD46-4, carrying a complex resistance region in an extensively-antibiotic resistant ST25 Acinetobacter baumannii
Accession number
Contact
ruth.hall@sydney.edu.au
Tn6184
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6185
Prof Ruth Hall
The University of Sydney
Contact
ruth.hall@sydney.edu.au
Tn6186
Dr Takatsugu Goto
Gifu University
  • Antibiotic Resistance
  • Carbapenem
  • Efflux functions
Characteristics
Tn6186 is an 8.5-kb composite transposon found in plasmid pBFUK1 of Bacteroides fragilis strain GAI92082. It contained six ORFs [including cfiA/ccrA (Metallo-beta-lactamase) and sugE homolog (putative small multidrug efflux protein], which were flanked by IS613 and IS615.
References

Goto, T., et al. (2013). "Complete sequence of pBFUK1, a carbapenemase-harboring mobilizable plasmid from Bacteroides fragilis, and distribution of pBFUK1-like plasmids among carbapenem-resistant B. fragilis clinical isolates." J Antibiot (Tokyo) 66(4): 239-242. DOI: 10.1038/ja.2012.109

Accession number
Contact
tagoto@gifu-u.ac.jp

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