The Transposon Registry

Displaying 541 - 560 of 2084
Tn6227
Dr Francesco Santoro
University of Siena
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6227 is a 7.9-kb transposon, found in Streptococcus mitis strain S022-V7-A3. It contained 12 coding sequences, which were similar to the ORFs from Tn916, including tet(M), xis and int
References
Santoro,F. and Iannelli,F. (Unpublished) Tn6227 of Streptococcus mitis
Accession number
Contact
santorof@unisi.it
Tn6228
Mr Tue Nielsen
GEUS
  • Metabolism
  • 2,4-dichlorophenoxyacetate dissimilatory
  • 2-methyl-4-chlorophenoxyacetic degradation
Characteristics
Tn6228 is a 32.5-kb composite transposon, found in plasmid pCADAB1 from Sphingomonas sp. strain ERG5. It contained two IS3 elements, flanking 25 ORFs, including genes for degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic (MCPA) acid (cadABR and tfdBCDEFKR).
References

Nielsen TK, Xu Z, Gözdereliler E, Aamand J, Hansen LH, Sørensen SR. Novel Insight into the Genetic Context of the cadAB Genes from a 4-chloro-2-methylphenoxyacetic Acid-Degrading Sphingomonas . Stevenson B, ed. PLoS ONE. 2013;8(12):e83346. DOI: 10.1371/journal.pone.0083346.

Accession number
Contact
tueknielsen@gmail.com
Tn6229
Ms Laura Mataseje
public health agency of Canada
  • Antibiotic Resistance
  • Chloramphenicol
  • Gentamicin
  • Rifampicin
Characteristics
Tn6229 is a 16.8-kb transposon found on plasmid pKp11-42 from Klebsiella pneumoniae strain N11-0042. It contained tnpA, tnpR, IS6100 and a class 1 integron, which carried the resistance genes for rifampicin (arr-3), aminoglycosides (aacA4) and chloramphenicol (cat).
References

Mataseje, L. F., et al. (2014). "Complete sequences of a novel blaNDM-1-harbouring plasmid from Providencia rettgeri and an FII-type plasmid from Klebsiella pneumoniae identified in Canada." J Antimicrob Chemother 69(3): 637-642. DOI: 10.1093/jac/dkt445

Accession number
Contact
laura.mataseje@phac-aspc.gc.ca
Tn6230
Dr Joseph Peters
Cornell University
  • Heavy Metal Resistance
Characteristics
Tn6230 is a 37-kb element, found in Salmonella enterica subsp. enterica ser. Senftenberg strain A4-543. It contained over 30 genes, including tnsABC from Tn7-like elements and genes encoding heavy metal resistance.
References

Peters, J. E., et al. (2014). "Heteromeric transposase elements: generators of genomic islands across diverse bacteria." Mol Microbiol 93(6): 1084-1092. DOI: 10.1111/mmi.12740

Contact
joe.peters@cornell.edu
Tn6231
Dr Hirokazu Yano
University of Idaho
Characteristics
Tn6231 is a Tn3-family transposon, found in plasmid pR28 from Pseudomonas moraviensis R28 strain R28-S. It contained tnpA, tnpR, orfA, orfB, tnpC,orfD, orfE and orfF.
References

Loftie-Eaton W, Yano H, Burleigh S, et al. Evolutionary Paths That Expand Plasmid Host-Range: Implications for Spread of Antibiotic Resistance. Molecular Biology and Evolution. 2016;33(4):885-897. DOI:10.1093/molbev/msv339.

Contact
hyano@uidaho.edu
Tn6232
Mr Philippe Glaser
Institut Pasteur
Contact
pglaser@pasteur.fr
Tn6233
Ms Yoriko Sakai
National Institute for Agro-Environmenta
  • Heavy Metal Resistance
  • Arsenate resistance
Characteristics
Tn6233 is an 8.8-kb transposon, found on plasmid pM7012 from Burkholderia sp. strain M701. It contained arsenic resistance gene cluster (asrBADCR), tnpA (related to Tn3-family) and tnpR.
References

Sakai, Y., et al. (2014). "A 2,4-dichlorophenoxyacetic acid degradation plasmid pM7012 discloses distribution of an unclassified megaplasmid group across bacterial species." Microbiology 160(Pt 3): 525-536. DOI: 10.1099/mic.0.074369-0

Accession number
Contact
kyoriko@affrc.go.jp
Tn6234
Dr VINCENZO DI PILATO
UNIVERSITY OF SIENA
  • Antibiotic Resistance
  • Cephalosporins
  • Gentamicin
  • Penicillin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6234 is a 29-kb Tn1699 derivative, found in a conjugative plasmid pFOX-7a from Klebsiella pneumoniae. It contained an In0/Tn402-like platform [carrying an aacA4 gene cassette, Tn6240 (containing blaFOX-8), sul1 gene in 3'CS and IS1326)], and mercury resistance gene cluster (merEDACPTR).
References

Di Pilato, V., et al. (2014). "Characterization of pFOX-7a, a conjugative IncL/M plasmid encoding the FOX-7 AmpC-type beta-lactamase, involved in a large outbreak in a neonatal intensive care unit." J Antimicrob Chemother 69(10): 2620-2624. DOI: 10.1093/jac/dku216

Accession number
Contact
vdipilato@unisi.it
Tn6235
Mr Wilco Knetsch
LUMC
  • Antibiotic Resistance
  • Streptomycin
Characteristics
Tn6235 is a 40-kb transposon found in Clostridium difficile 078. It contained aphA1 gene, conferring streptomycin resistance.
References

Knetsch, C. W., et al. (2014). "Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011." Eurosurveillance 19(45): 20954. DOI: 10.2807/1560-7917.ES2014.19.45.20954

Contact
c.w.knetsch@lumc.nl
Tn6236
Prof Gongzheng Hu
Henan Agricultural University
Contact
gongzhenghu64@126.com
Tn6237
Dr racha Beyrouthy
Auvergne University
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn6237 is a 21.9-kb IS1R-based composite transposon, found in the E. coli chromosome and plasmid pRA35. It contained two IS1R elements flanking a truncated and inverted Tn1999.2 (containing blaOXA-48), 9 genes (pemI, pemK, mucA, mucB, resD, parA, parB, nuc, and korC) and 18 ORFs encoding hypothetical proteins.
References

Beyrouthy R, Robin F, Delmas J, et al. IS1R-Mediated Plasticity of IncL/M Plasmids Leads to the Insertion of blaOXA-48 into the Escherichia coli Chromosome. Antimicrobial Agents and Chemotherapy. 2014;58(7):3785-3790. DOI: 10.1128/AAC.02669-14.

Contact
racha_beyrouthy@yahoo.fr
Tn6238
Dr María Paula Quiroga
IMPaM (UBA-CONICET) Facultad de Medicina
  • Antibiotic Resistance
  • Amikacin
  • Ampicillin
  • Fluoroquinolone
  • Kanamycin
  • Streptomycin
Characteristics
Tn6238 is an 8-kb Tn1331-like transposon, found in Klebsiella pneumoniae strain KpF7. It contained tnpA-tnpR (Tn3 family), blaTEM-1, and two gene cassettes carrying three resistance genes [aac(6′)-Ib-cr7 (conferring resistance to aminoglycosides and fluoroquinolones), aadA1 and blaOXA-9].
References

Quiroga MP, Orman B, Errecalde L, Kaufman S, Centrón D. Characterization of Tn6238 with a New Allele of aac(6′)-Ib-cr. Antimicrobial Agents and Chemotherapy. 2015;59(5):2893-2897. DOI: 10.1128/AAC.03213-14.

Accession number
Contact
paulaquiro@yahoo.com.ar
Tn6239
Dr Liang Chen
PHRI, NJMS-Rutgers
Contact
chen11@njms.rutgers.edu
Tn6240
Dr VINCENZO DI PILATO
UNIVERSITY OF SIENA
  • Antibiotic Resistance
  • Cephalosporins
Characteristics
Tn6240 is a 9.6-kb transposon, found within Tn6234 in a conjugative plasmid pFOX-7a from Klebsiella pneumoniae. It contained blaFOX-7, mdrL, lysR, ISApu1, ISApu2 and three genes encoding hypothetical proteins.
References

Di Pilato, V., et al. (2014). "Characterization of pFOX-7a, a conjugative IncL/M plasmid encoding the FOX-7 AmpC-type beta-lactamase, involved in a large outbreak in a neonatal intensive care unit." J Antimicrob Chemother 69(10): 2620-2624. DOI: 10.1093/jac/dku216

Accession number
Contact
vdipilato@unisi.it
Tn6241
Dr Deng Fengru
China Agricultural University
Contact
dengfengru2005@163.com
Tn6242
Miss Jessica McKinnon
iThree Institute
  • Antibiotic Resistance
  • Ampicillin
  • Azithromycin
  • Kanamycin
  • Streptomycin
  • Sulphonamide
  • Trimethoprim
Characteristics
Tn6242 is a 19.7-kb composite transposon, found in the chromosome of Escherichia coli ST405 strain 2009-27. It contains four modules that each carries resistance genes flanked by two IS26 elements, including a class 1 integron with dfrA17 and aadA5 gene cassettes, a variant of Tn6029, and mphA.
References

Roy Chowdhury, P., McKinnon, J., Liu, M., & Djordjevic, S. P. (2019). Multidrug Resistant Uropathogenic Escherichia coli ST405 With a Novel, Composite IS26Transposon in a Unique Chromosomal Location. Frontiers in microbiology, 9, 3212. DOI: 10.3389/fmicb.2018.03212

Contact
jmjmckinnon@gmail.com
Tn6243
Dr Hannah Wexler
GLAVA HCS
Contact
hwexler@ucla.edu
Tn6244
Prof Gong-zheng Hu
Henan Agricultural University
Contact
yaolilab@126.com
Tn6245
Prof Gong-zheng Hu
Henan Agricultural University
Contact
yaolilab@126.com
Tn6246
Prof Du Xiang-Dang
Henan Agricultural University
  • Antibiotic Resistance
  • Chloramphenicol
  • Florfenicol
Characteristics
Tn6246 is a 5.1-kb composite transposon, found in Enterococcus faecium strain P36. It contained two ISEnfa14 elements, flanking three ORFs, encoding two hypothetical proteins and FexB (chloramphenicol/florfenicol exporter).
References
Du,X.-D. (Unpublished) Tn6246,a novel florfenicol resistance composite transposon in enterococci of swine origin
Accession number
Contact
xiangdangdu@gmail.com

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