The Transposon Registry

Displaying 601 - 620 of 2138
Tn6287
Dr Lisbeth de Vries
Metropolitan University College
Contact
lidv@phmetropol.dk
Tn6288
Dr Lisbeth de Vries
Metropolitan University College
Contact
lidv@phmetropol.dk
Tn6289
Dr Lisbeth de Vries
Metropolitan University College
Contact
lidv@phmetropol.dk
Tn6290
Dr James Hall
University of York
Characteristics
Tn6290 is a 42-kb transposon, found in Pseudomonas putida strain KT2440.
References

Hall JPJ, Williams D, Paterson S, Harrison E, Brockhurst MA. Positive selection inhibits gene mobilisation and transfer in soil bacterial communities. Nature ecology & evolution. 2017;1(9):1348-1353. DOI: 10.1038/s41559-017-0250-3.

Accession number
Contact
james.hall@york.ac.uk
Tn6291
Dr James Hall
University of York
Characteristics
Tn6291 is a 22.3-kb transposon, found in Pseudomonas fluorescens strain SBW25. It carried an array of cargo genes with putative cytochrome c/d oxidase functions.
References

Hall JPJ, Williams D, Paterson S, Harrison E, Brockhurst MA. Positive selection inhibits gene mobilisation and transfer in soil bacterial communities. Nature ecology & evolution. 2017;1(9):1348-1353. DOI: 10.1038/s41559-017-0250-3.

Accession number
Contact
james.hall@york.ac.uk
Tn6292
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Quinalone
Characteristics
Tn6292 is a Tn3-family transposon. Its remnants, designated (ΔTn6292-3′ and ΔTn6292-5′), have been found in plasmid pP378-IMP (Pseudomonas aeruginosa strain P378) and pIMP-HZ1 (Klebsiella pneumoniae strain Kp1). It contains ISknp19, IS26 and qnrS1 (conferring resistance to quinolone).
References

Feng W, Zhou D, Wang Q, et al. Dissemination of IMP-4-encoding pIMP-HZ1-related plasmids among Klebsiella pneumoniae and Pseudomonas aeruginosain a Chinese teaching hospital. Scientific Reports. 2016;6:33419. DOI: 10.1038/srep33419.

Yang L, Li P, Liang B, et al. Multidrug-resistant Citrobacter freundii ST139 co-producing NDM-1 and CMY-152 from China. Scientific Reports. 2018;8:10653. DOI: 10.1038/s41598-018-28879-9.

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6293
Dr Katherine Hargreaves
University of Leicester
  • Antibiotic Resistance
  • Streptomycin
Characteristics
Tn6293 is a 104-kb conjugative transposon, found in Clostridium difficile CD105HS27 genomes. It contained several genes with predicted functions that could potentially enhance cell survival and growth such as aadE (aminoglycoside resistance), a LexA repressor and 23S rRNA methyltransferase RlmN. It also has predicted transposases and conjugation transfer genes as well as homologs of plasmid maintenance and replication protein encoding genes; parA and parB, and repA.
References

Hargreaves KR, Thanki AM, Jose BR, Oggioni MR, Clokie MRJ. Use of single molecule sequencing for comparative genomics of an environmental and a clinical isolate of Clostridium difficile ribotype 078. BMC Genomics. 2016;17:1020. DOI: 10.1186/s12864-016-3346-2.

Accession number
Contact
kh283@le.ac.uk
Tn6294
Dr Kazuaki Matsui
Kindai University
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6294 is an 8574-bp transposon, found in Paenibacillus sp. strain EOA1. It contained genes encoding mercury resistance determinants (merR,E,T,P,A & merR2, B1).
References

Matsui, K., S. Yoshinami, M. Narita, M. F. Chien, L. Phung, S. Silver, and G. Endo. (2016). "Mercury resistance transposons in Bacilli strains from different geographical regions." FEMS Microbiology Letters 363(5): fnw013-fnw013. DOI: 10.1093/femsle/fnw013

Accession number
Contact
kmatsui@civileng.kindai.ac.jp
Tn6295
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Erythromycin
Characteristics
Tn6295 is a 6-kb composite transposon, found in plasmid p2246-CTXM from Shigella boydii strain 2246. It contained two IS26 elements, flanking ISCR12 element and a macrolide-resistance operon erm(B)L (leading peptide)-erm(B) (methylase).
References

Wang L, Liu L, Liu D, et al. The First Report of a Fully Sequenced Resistance Plasmid from Shigella boydii. Frontiers in Microbiology. 2016;7:1579. DOI: 10.3389/fmicb.2016.01579.

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6296
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn6296, a Tn3-family transposon, found in Enterobacteriaceae strains. It was a Tn1722-based unit transposon that was generated by the insertion of the core blaKPC-2 region into Tn1722.
References

Wang D, Zhu J, Zhou K, et al. Genetic characterization of novel class 1 Integrons In0, In1069 and In1287 to In1290, and the inference of In1069-associated integron evolution in Enterobacteriaceae. Antimicrobial Resistance and Infection Control. 2017;6:84. DOI: 10.1186/s13756-017-0241-9.

Jiang Y, Yu D, Wei Z et al. Complete nucleotide sequence of Klebsiella pneumoniae multidrug resistance plasmid pKP048, carrying blaKPC-2, blaDHA-1, qnrB4, and armA. Antimicrob. Agents Chemother. 54(9), 3967–3969 (2010). DOI: 10.1128/AAC.00137-10

Feng J, Qiu Y, Yin Z, et al. Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii. J Antimicrob Chemother 2015;70:2987-2991. DOI: 10.1093/jac/dkv232

Wang L, Fang H, Feng J et al. Complete sequences of KPC-2-encoding plasmid p628-KPC and CTX-M-55-encoding p628-CTXM coexisted in Klebsiella pneumoniae. Front. Microbiol. 6 838 (2015). DOI: 10.3389/fmicb.2015.00838

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6297
Mrs Khadidja Yousfi
laboratoire de sante publique du quebec
  • Antibiotic Resistance
  • Ampicillin
  • Azithromycin
  • Cefotaxime
  • Ceftazidime
  • Chloramphenicol
  • Gentamicin
  • Penicillin
  • Quinalone
  • Streptomycin
  • Sulphonamide
  • Tetracycline
  • Trimethoprim
  • Antispetic Resistance
  • Quaternary ammonium compound
  • Efflux functions
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6297 is a 78-kb Tn1696-derivative transposon, found in plasmid pSx1 from Shewanella xiamenensis strain T17. It contained three class 1 integrons and transposons associated with drug resistance genes, which were an In27 class 1 integron harboring the dfrA12-orfF-aadA2 array, msr(E) and mph(E) associated with IS26; a new efflux pump multidrug resistance (acrA, acrB, and oep) composite transposon flanked by two ISEc29s; Tn-tet harboring tetR and tetA(C); a class 1 integron with the qacG gene cassette; qnrVC6 and dfrA23 associated with ISCR1; and a complex class 1 integron In4-like containing aacC1, aadA1, blaVEB-16, catA2, sul1D, cmlA9, tetR, tetA(G), aac(6¢)-II, blaPSE-1 and mer operon.
References

Yousfi, K., et al. (2017). "A Novel Plasmid, pSx1, Harboring a New Tn1696 Derivative from Extensively Drug-Resistant Shewanella xiamenensis Encoding OXA-416." Microb Drug Resist 23(4): 429-436. DOI: 10.1089/mdr.2016.0025

Accession number
Contact
khadidja.yousfi@hotmail.com
Tn6298
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6298 is a 3-kb Tn5706-derived transposon, found in swine manure by functional metagenomics. It contains IS1596 and tet(H), conferring tetracycline resistance. Its boundaries and mobility inferred from genomic comparisons. Carries a tetracycline gene tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6299
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Chloramphenicol
  • Florfenicol
  • Streptomycin
  • Sulphonamide
  • Tetracycline
Characteristics
Tn6299 is a 21.4-kb Tn3-related transposon, found in swine manure by functional metagenomics. Its boundaries and mobility inferred from genomic comparisons. It carries tetracycline (tetY), chloramphenicol / florfenicol (floR), aminoglycoside (strAB), and sulfonamide (sul1) resistance genes, with only the tetracycline tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6300
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Sulphonamide
  • Tetracycline
Characteristics
Tn6300 is a 7.2-kb ISCR2-related transposon, found in swine manure by functional metagenomics.Its boundaries and mobility inferred from genomic comparisons. It carries tetracycline (tet(31)) and sulfonamide (sul2) resistance genes, with only the tetracycline tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6301
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Chloramphenicol
  • Florfenicol
  • Streptomycin
  • Sulphonamide
  • Tetracycline
Characteristics
Tn6301 is a 12.1-kb ISRC2-related transposon, found in swine manure by functional metagenomics. Its boundaries and mobility inferred from genomic comparisons. It carries tetracycline (tet(Y)-tetR), chloramphenicol/florfenicol (floR), aminoglycoside (strAB), and sulfonamide (sul2) resistance genes, with only the tetracycline tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6302
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Sulphonamide
  • Tetracycline
Characteristics
Tn6302 is an 11-kb ISCR2-related transposon, found in swine manure by functional metagenomics. Its boundaries and mobility inferred from genomic comparisons. It carries two ISCR2 elements, tetracycline (tetR-tet(59)) and sulphonamide (sul2) resistance genes, with only the tetracycline resistance tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6303
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6303 is a 4.6-kb IS605-related transposon, found in swine manure by functional metagenomic. Its boundaries and mobility inferred from genomic comparisons. It carries a tetracycline resistance gene (tet(A)-tetR) tested experimentally.
References

Leclercq SO, Wang C, Zhu Y, Wu H, Du X, Liu Z, Feng J. 2016. Diversity of the tetracycline mobilome within a Chinese pig manure sample. Appl Environ Microbiol 82:6454 – 6462. doi: 10.1128/AEM.01754-16.

Accession number
Contact
sebastien.leclercq@inrae.fr
Tn6304
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
Contact
sebastien.leclercq@inrae.fr
Tn6305
Dr. Leclercq Sébastien
Chinese Academy of Science (CAS)
Contact
sebastien.leclercq@inrae.fr
Tn6306
Mr Jing yong Sun
Department of Clinical Microbiology
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn6306 is a 13.8-kb composite transposon, found in Raoultella ornithinolytica RJ46C. It contains two ISEcl1-like elements flanking blaIMI-R, blaIMI-3 (carbapenem resistance), ISEc36 and parBA (plasmid partitioning proteins).
References

Zhang, F., et al. (2017). "A novel transposon, Tn6306, mediates the spread of blaIMI in Enterobacteriaceae in hospitals." International Journal of Infectious Diseases 65: 22-26. DOI: 10.1016/j.ijid.2017.09.014

Accession number
Contact
13671578899@126.com

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