The Transposon Registry

Displaying 661 - 680 of 2084
Tn6347
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Efflux functions
Characteristics
Tn6347 is a 3-kb transposon found on plasmid p12208-IMP in Klebsiella pneumoniae strain 12208. It contains tnpR, cation efflux pump (czcD) gene, and IS4321.
References

Liang, Q., Jiang, X., Hu, L., Yin, Z., Gao, B., Zhao, Y., … Zhou, D. (2019). Sequencing and Genomic Diversity Analysis of IncHI5 Plasmids. Frontiers in microbiology, 9, 3318. DOI: 10.3389/fmicb.2018.03318

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6348
Prof Nilton Lincopan
University of Sao Paulo
Contact
lincopan@usp.br
Tn6349
Dr Alberto Antonelli
University of Florence
Contact
albertoanton88@gmail.com
Tn6350
Ms Helena Turano
University of Sao Paulo
  • Virulence Determinants
  • Bacteriocin production
Characteristics
Tn6350 is a 7.4-kb transposon, found in Pseudomonas aeruginosa strain ET02. It contains orf1, transposase (int), resolvase (tnpR), a cytotoxic subunit of pyocin S8 (pys8), an immunity subunit of pyocin S8 (imm), and three more hypothetical proteins (ofr4, orf7, and orf8).
References

Turano H, Gomes F, Barros-Carvalho GA, et al. Tn6350, a Novel Transposon Carrying Pyocin S8 Genes Encoding a Bacteriocin with Activity against Carbapenemase-Producing Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2017;61(5):e00100-17. Published 2017 Apr 24. DOI: 10.1128/AAC.00100-17

Accession number
Contact
helenagabrielaturano@hotmail.com
Tn6351
Mr Du Xiaochen
Institute Of Microbiology Chinese Academ
Contact
m15103321615@163.com
Tn6352
Mr João Botelho
UCIBIO/REQUIMTE, Microbiology, FFUP
  • Antibiotic Resistance
  • Carbapenem
  • Gentamicin
Characteristics
Tn6352 is an 11-kb transposon, found on plasmid pJB12 in Pseudomonas aeruginosa. It contains ISPa17 and Tn402-like transposon [containing class 1 integron (aacA7-blaVIM-2-aacC1-aacA4 gene cassette, sul1, orf5), tniB and tniA].
References

Characterization of the pJB12 Plasmid from Pseudomonas aeruginosa Reveals Tn6352, a Novel Putative Transposon Associated with Mobilization of the blaVIM-2-Harboring In58 Integron. DOI: 10.1128/AAC.02532-16

Accession number
Contact
joaobotelho9@hotmail.com
Tn6353
Miss Kaitlin Tagg
The Westmead Institute
Contact
ktag4715@uni.sydney.edu.au
Tn6354
Dr D. Ashley Robinson
University of Mississippi Medical Center
Contact
darobinson@umc.edu
Tn6355
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6356
Mr João Botelho
UCIBIO/REQUIMTE, Microbiology, FFUP
  • Antibiotic Resistance
  • Carbapenem
  • Gentamicin
  • Efflux functions
Characteristics
Tn6356 is a 15.6-kb transposon found on plasmid pJB37 in Pseudomonas aeruginosa strain FFUP_PS_37. It contains ΔrepA-parA-resA segment, an In58 class 1 integron and a ΔtnpR-orfABCD module similar to the one identified in the Tn1403 transposon (containing IS6100, sodium-independent anion transporter and uspA). The blaVIM-2 gene was associated with the In58, a genetic platform that carries three aminoglycoside resistance genes (aacA7, aacA4 and aacC1) and sul1 in its 3' CS.
References

João Botelho, Filipa Grosso, Sandra Quinteira, Aymen Mabrouk, Luísa Peixe, The complete nucleotide sequence of an IncP-2 megaplasmid unveils a mosaic architecture comprising a putative novel blaVIM-2-harbouring transposon in Pseudomonas aeruginosa, Journal of Antimicrobial Chemotherapy, Volume 72, Issue 8, August 2017, Pages 2225–2229, doi: 10.1093/jac/dkx143

Accession number
Contact
joaobotelho9@hotmail.com
Tn6357
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6358
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6359
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6360
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Bleomycin
  • Carbapenem
  • Quinalone
Characteristics
Tn6360 is a 17-kb Tn3-family transposon, found on plasmid pNDM-BTR in Escherichia coli. Two IS26 elements were found at its border, as a composite transposon structure. Tn6360 was composed of an accessory region carrying blaNDM-1 and an intact Tn6292 element carrying qnrS1. The accessory region comprised an IS26, a 427-bp truncated tnpA, and an 8.3-kb Tn3000 remnant (IS3000-ΔISAba125-blaNDM-1-bleMDL-trpF-tat-ΔcutA1-groES-ΔgroEL).
References

Yang L, Li P, Liang B, et al. Multidrug-resistant Citrobacter freundii ST139 co-producing NDM-1 and CMY-152 from China. Sci Rep. 2018;8(1):10653. Published 2018 Jul 13. DOI: 10.1038/s41598-018-28879-9

Zhao, Yachao & Wang, Lijun & Zhang, Zhiyi & Feng, Jiao & Kang, Huaixing & Fang, Li-Qun & Jiang, Xiaoyuan & Zhang, Defu & Zhan, Zhe & Zhou, Dongsheng & Tong, Yigang. (2017). Structural genomics of pNDM-BTR harboring In191 and Tn 6360 , and other bla NDM -carrying IncN1 plasmids. Future Microbiology. 12. DOI: 10.2217/fmb-2017-0067. 

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6361
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Carbapenem
  • Quinalone
Characteristics
Tn6361 is a transposon, found on plasmid pMR3-OXA181 in Morganella morganii strain MRSN22709. Two IS26 elements were found at its border similar to composite transposon structure. It was based on Tn6292 (tnpA interrupted by ISKpn19–res–tnpR followed by qnrS1–ISEcl2–IS26–orf198) with insertion of IS26, a 1.7-kb remnant (containing only tnpA) of Tn6346, IS3000 and a ColE2-type repA1 interrupted by a truncated ISEcp1-blaOXA-181 transposition unit.
References

Yang L, Li P, Liang B, et al. Multidrug-resistant Citrobacter freundii ST139 co-producing NDM-1 and CMY-152 from China. Sci Rep. 2018;8(1):10653. Published 2018 Jul 13. DOI: 10.1038/s41598-018-28879-9

Zhao, Yachao & Wang, Lijun & Zhang, Zhiyi & Feng, Jiao & Kang, Huaixing & Fang, Li-Qun & Jiang, Xiaoyuan & Zhang, Defu & Zhan, Zhe & Zhou, Dongsheng & Tong, Yigang. (2017). Structural genomics of pNDM-BTR harboring In191 and Tn 6360 , and other bla NDM -carrying IncN1 plasmids. Future Microbiology. 12. DOI: 10.2217/fmb-2017-0067. 

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6362
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Efflux functions
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6362 is a 10.7-kb transposon found on plasmid p505108-MDR in Cronobacter sakazakii strain 505108. It contains IS102 inserted into IS4321, a pbrR-zntA-lspA region (probably involved in zinc uptake), part of Tn1696 backbone [urf2Y and mercury resistance operon (merEDACPTR)].
References

Shi L, Liang Q, Zhan Z, et al. Co-occurrence of 3 different resistance plasmids in a multi-drug resistant Cronobacter sakazakii isolate causing neonatal infections. Virulence. 2017;9(1):110–120. DOI: 10.1080/21505594.2017.1356537

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6363
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn6363 is a 6.1-kb composite transposon, found on plasmid p505108-T6SS in Cronobacter sakazakii strain 505108. It contains two IS903B flanking orf585, yqhD (Alcohol dehydrogenase), orf894 and aphA1 aminoglycoside resistance genes.
References

Shi L, Liang Q, Zhan Z, et al. Co-occurrence of 3 different resistance plasmids in a multi-drug resistant Cronobacter sakazakii isolate causing neonatal infections. Virulence. 2017;9(1):110–120. DOI: 10.1080/21505594.2017.1356537

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6364
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6365
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com
Tn6366
Prof Dongsheng Zhou
Beijing Institute of Microbiology and Epidemiology
Contact
dongshengzhou1977@gmail.com

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