The Transposon Registry

Displaying 701 - 720 of 2138
Tn6387
Mr João Botelho
University of Porto
Contact
joaobotelho9@hotmail.com
Tn6388
Universidade Federal de São Paulo - UNIFESP/EPM
Tn6389
Mr João Botelho
University of Porto
Contact
joaobotelho9@hotmail.com
Tn6390
Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing
  • Antibiotic Resistance
  • Colistin
Characteristics
Tn6390 is a 4.5-kb composite transposon, founc on plasmid pRC960-2 in Shigella flexneri Y strain C960. It contains two ISApl1 elements, flanking mcr-1 collistin resistance and pap2 genes.
References

Liang B, Roberts AP, Xu X, et al. Transferable Plasmid-Borne mcr-1 in a Colistin-Resistant Shigella flexneri Isolate. Appl Environ Microbiol. 2018;84(8):e02655-17. Published 2018 Apr 2. DOI: 10.1128/AEM.02655-17

Accession number
Tn6391
Mr João Botelho
University of Porto
  • Antibiotic Resistance
  • Carbapenem
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6391 is a 17.4-kb transposon, found in Pseudomonas aeruginosa strain FFUP_PS_CB5. It contains IS1071, ISPa38, TnpR, class 1 integron (blaVIM-2-qacED1-sul1 genes), IS6100 and mercury resistance genes.
Accession number
Contact
joaobotelho9@hotmail.com
Tn6392
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Carbapenem
  • Kanamycin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6392 is a 14.5-kb transposon, found on plasmid p1160-VIM in Pseudomonas aeruginosa strain 1160. It contains Tn5563 backbone (tnpR, urf2, pilT, tnpA and merPTR resistance genes) and In1394 (Tn402 tniABQR module and aacA4-blaVIM-24-aacA4 genes).
References

Zeng L, Zhan Z, Hu L, et al. Genetic Characterization of a blaVIM-24-Carrying IncP-7β Plasmid p1160-VIM and a blaVIM-4-Harboring Integrative and Conjugative Element Tn6413 From Clinical Pseudomonas aeruginosa. Front Microbiol. 2019;10:213. Published 2019 Feb 26. DOI: 10.3389/fmicb.2019.00213

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6393
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Azithromycin
  • Chloramphenicol
  • Erythromycin
  • Quinalone
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6393 is a 47.1-kb transposon, found on plasmid p1160-VIM in Pseudomonas aeruginosa strain 1160. It contains Tn4103 backbone with an insertion of In1395 element [integron-1 (ereA1c-catB3q-ISPa62-gcu61-aadA1a-ISPa62-qacED1-sul1), Tn4662b remnant, truncated IScs605, msr(E)-mph(E) unit, two truncated ISCR1, integron-2 (qnr-fepC-mdlB-folA-qacED1-sul1-orf5-orf6) and IS6100] and Tn5393c (strA-starB).
References

Zeng L, Zhan Z, Hu L, et al. Genetic Characterization of a blaVIM-24-Carrying IncP-7β Plasmid p1160-VIM and a blaVIM-4-Harboring Integrative and Conjugative Element Tn6413 From Clinical Pseudomonas aeruginosa. Front Microbiol. 2019;10:213. Published 2019 Feb 26. DOI: 10.3389/fmicb.2019.00213

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6394
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Carbapenem
  • Kanamycin
Characteristics
Tn6394 is a 7.2 transposon, found on plasmid p60512-IMP in Pseudomonas aeruginosa strain 60512. It contains ISPa17 and In992 [ISCfr1, aacA7-blaIMP-1 gene cassettes and truncated tniA].
References

Zhe Zhan, Lingfei Hu, Xiaoyuan Jiang, Lijun Zeng, Jiao Feng, Weili Wu, Weijun Chen, Huiying Yang, Wenhui Yang, Bo Gao, Zhe Yin, Dongsheng Zhou, Plasmid and chromosomal integration of four novel blaIMP-carrying transposons from Pseudomonas aeruginosa, Klebsiella pneumoniae and an Enterobacter sp., Journal of Antimicrobial Chemotherapy, Volume 73, Issue 11, November 2018, Pages 3005–3015, DOI: 10.1093/jac/dky288

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6395
Prof Dongsheng Zhou
References

 

Contact
dongshengzhou1977@gmail.com
Tn6396
Prof Dongsheng Zhou
Contact
dongshengzhou1977@gmail.com
Tn6397
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Azithromycin
  • Carbapenem
  • Kanamycin
  • Heavy Metal Resistance
  • Arsenate resistance
  • Copper Resistance
  • Metabolism
  • Cellulose biosynthesis
Characteristics
Tn6397 is a 114-kb conjugative transposon, found in Enterobacter cloacae strain A1137. It contains In73 and resistance genes including blaIMP-8–aacA4′-3, macAB, arsR. It consisted of the backbone and a single 63.7 kb accessory region inserted at a site upstream of orf318 and its backbone contained the tyrosine recombinase gene int, maintenance markers (parAB, umuCD, ssb, ecm, and ecoRII) and an F-type T4SS (rlx and tivF) for conjugal transfer. The Tn6397 accessory region carried Tn6378, the bcs region (bacterial cellulose biosynthesis), the arsR region (arsenical resistance), the cop (copper resistance) remnant and several Tn3-family transposon remnants and intact or residue IS elements.
References

Zhe Zhan, Lingfei Hu, Xiaoyuan Jiang, Lijun Zeng, Jiao Feng, Weili Wu, Weijun Chen, Huiying Yang, Wenhui Yang, Bo Gao, Zhe Yin, Dongsheng Zhou, Plasmid and chromosomal integration of four novel blaIMP-carrying transposons from Pseudomonas aeruginosa, Klebsiella pneumoniae and an Enterobacter sp., Journal of Antimicrobial Chemotherapy, Volume 73, Issue 11, November 2018, Pages 3005–3015, DOI: 10.1093/jac/dky288

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6398
Prof Dongsheng Zhou
Contact
dongshengzhou1977@gmail.com
Tn6399
Prof Dongsheng Zhou
Characteristics
Tn6399 is an 8.3-kb transposon, found on plasmid pA324-IMP in Klebsiella pneumoniae strain A324. It contains IS1618 and genes encoding S-formylglutathione hydrolase (fgh), Glyoxalase resistance protein (glo), S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase (adh) and Negative transcriptional regulator of formaldehyde detoxification operon (frmR).
References

Liang, Quanhui et al. “Sequencing and Genomic Diversity Analysis of IncHI5 Plasmids.” Frontiers in microbiology vol. 9 3318. 14 Jan. 2019, doi: 10.3389/fmicb.2018.03318

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6400
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Carbapenem
  • Chloramphenicol
  • Fluoroquinolone
  • Kanamycin
  • Rifampicin
  • Spectinomycin
  • Streptomycin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6400 is a 23.8-kb transposon, found on plasmid pKP04VIM in Klebsiella pneumoniae strain KP04. It contains IS5075, Tn1696 backbone (merEDACPTR resistance genes), In916 (blaVIM-1-aacA4-aphA15-aadA1b-catB2), IS26, and In37 (aacAcr,-blaOXA-1-catB3-arr3-sul1-IS6100).
References

Liang Q, Jiang X, Hu L, et al. Sequencing and Genomic Diversity Analysis of IncHI5 Plasmids. Front Microbiol. 2019;9:3318. Published 2019 Jan 14. DOI: 10.3389/fmicb.2018.03318

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6401
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Carbapenem
  • Chloramphenicol
  • Kanamycin
  • Rifampicin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6401 is a transposon found plasmid pKpNDM1 in Raoultella planticola strain KpNDM1. It contains IS5075, truncated Tn696 backbone (tnpA-tnpR-merR), In1006 [arr3, sul1, ISCR1, blaNDM-1, ISCR1, blaCTX-M-9], In127 [aadA2, sul1, IS1326, IS1353] and In609 [sul1, catB8, aacA4-17].
References

Liang Q, Jiang X, Hu L, et al. Sequencing and Genomic Diversity Analysis of IncHI5 Plasmids. Front Microbiol. 2019;9:3318. Published 2019 Jan 14. DOI: 10.3389/fmicb.2018.03318

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6402
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Trimethoprim
Characteristics
Tn6402 is a 9.4-kb composite transposon found on plasmid p13190-VIM in Klebsiella pneumoniae strain 13190. It contains two IS26 elements, flanking In27 (dfrA12-gcuF-aadA2-sul1) and ISCR1.
References

Liang Q, Jiang X, Hu L, et al. Sequencing and Genomic Diversity Analysis of IncHI5 Plasmids. Front Microbiol. 2019;9:3318. Published 2019 Jan 14. DOI: 10.3389/fmicb.2018.03318

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6403
Prof Dongsheng Zhou
  • Antibiotic Resistance
  • Azithromycin
  • Carbapenem
  • Kanamycin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6403 is a 30-kb transposon, found in Pseudomonas aeruginosa strain 6762 as part of Tn6413. It was identified as Tn6346 derivatives by containing [tnpA-tnpR-merEDAPTR resistance operon] with an insertion of IS1071 and In127 [ISPa82, aadA2, sul1, IS26-msr(E)-mph(E)-IS26 unit, In1443 (ISPa82, blaVIM-4, aacA7, aacA4, sul1, IS6100)]
References

Zeng L, Zhan Z, Hu L, et al. Genetic Characterization of a blaVIM-24-Carrying IncP-7β Plasmid p1160-VIM and a blaVIM-4-Harboring Integrative and Conjugative Element Tn6413 From Clinical Pseudomonas aeruginosa. Front Microbiol. 2019;10:213. Published 2019 Feb 26. DOI: 10.3389/fmicb.2019.00213

Accession number
Contact
dongshengzhou1977@gmail.com
Tn6404
Dr. Kai Zhou
  • Antibiotic Resistance
  • Carbapenem
  • Kanamycin
  • Antispetic Resistance
  • Quaternary ammonium compound
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6404 is a composite transposon, found on plasmid pKP1814-1 Klebsiella pneumoniae strain KP1814. It contains two IS5075 flanking Tn1696 remnant (tnpA-tnpR), In809-like (blaIMP-4, qacG, aacA4), Tn5563a-like (tnpA-tniR) and merEDAFPTR of Tn5053.
References

Zhou K, Yu W, Shen P, et al. A novel Tn1696-like composite transposon (Tn6404) harboring bla IMP-4 in a Klebsiella pneumoniae isolate carrying a rare ESBL gene bla SFO-1. Sci Rep. 2017;7(1):17321. Published 2017 Dec 11. DOI: 10.1038/s41598-017-17641-2

Accession number
Contact
kai_zhou@zju.edu.cn
Tn6405
Dr Gabriel Ramírez Vargas
Contact
garava291@hotmail.es
Tn6406
Dr. Andrew Cameron
Contact
andrew.a.cameron@agr.gc.ca

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