The Transposon Registry

Displaying 521 - 540 of 2138
Tn6207
Dr Zhenyu Xuan
University of Texas at Dallas
  • Antibiotic Resistance
  • Streptomycin
  • Tetracycline
Characteristics
Tn6207 is a composite transposon found in Acinetobacter baumannii strain MDR-ZJ06. It contained tetracycline efflux pump and its regulator genes, tetA(B) and tetR, and a truncated Tn5393-like island containing aminoglycoside resistance genes strB and strA.
References

Zhu L, Yan Z, Zhang Z, et al. Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements. Bereswill S, ed. PLoS ONE. 2013;8(6):e66584. DOI: 10.1371/journal.pone.0066584.

Accession number
Contact
zxx091000@utdallas.edu
Tn6208
Dr Zhenyu Xuan
University of Texas at Dallas
  • Antibiotic Resistance
  • Sulphonamide
Characteristics
Tn6208 is a 9.2-kb composite transposon found in Acinetobacter baumannii strain BJAB07104. It contained two ISAba1 elements, flanking genes for transposition (tniCABDE), sul2 and GlmM genes.
References

Zhu L, Yan Z, Zhang Z, et al. Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements. Bereswill S, ed. PLoS ONE. 2013;8(6):e66584. DOI: 10.1371/journal.pone.0066584.

Accession number
Contact
zxx091000@utdallas.edu
Tn6209
Dr Zhenyu Xuan
University of Texas at Dallas
  • Antibiotic Resistance
  • Sulphonamide
Characteristics
Tn6209 is an 8.4-kb transposon found in Acinetobacter baumannii strain BJAB0868. It is similar to Tn6208 [containing sul2 gene], but has only the left ISAba1 element.
References

Zhu L, Yan Z, Zhang Z, et al. Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements. Bereswill S, ed. PLoS ONE. 2013;8(6):e66584. DOI: 10.1371/journal.pone.0066584.

Accession number
Contact
zxx091000@utdallas.edu
Tn6210
Dr Zhenyu Xuan
University of Texas at Dallas
  • Antibiotic Resistance
  • Amikacin
  • Kanamycin
Characteristics
Tn6210 is a composite transposon found in plasmid pBJAB07104 and p2BJAB0868 from Acinetobacter baumannii. It contained aphA1 gene, which was flanked by two ISAba26 elements.
References

Zhu L, Yan Z, Zhang Z, et al. Complete Genome Analysis of Three Acinetobacter baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements. Bereswill S, ed. PLoS ONE. 2013;8(6):e66584. DOI: 10.1371/journal.pone.0066584.

Contact
zhenyu.xuan@utdallas.edu
Tn6211
Prof Russell Poulter
University Otago
Characteristics
Tn6211 is a 4.9-kb transposon found within the ICES of Pseudomonas syringae pv. actinidiae and P. syringae pv. avellanae. It contained three ORFs, including a transposase gene and a methyl-accepting chemotaxis protein gene.
References

Butler MI, Stockwell PA, Black MA, Day RC, Lamont IL, Poulter RTM. Pseudomonas syringae pv. actinidiae from Recent Outbreaks of Kiwifruit Bacterial Canker Belong to Different Clones That Originated in China. Gribaldo S, ed. PLoS ONE. 2013;8(2):e57464. DOI: 10.1371/journal.pone.0057464.

Accession number
Contact
russell.poulter@otago.ac.nz
Tn6212
Dr Margi Butler
University of Otago
  • Efflux functions
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6211 is a 16.3-kb transposon found within the ICES of Pseudomonas syringae pv. actinidiae and P. syringae pv. avellanae. It encodes a XerC-type tyrosine recombinase and includes multiple ORFs encoding a C4 dicarboxylate transporter, inorganic pyrophosphatase, enolase, a voltage-gated chloride channel, mercury resistance and a methyl-accepting chemotaxis protein.
References

Butler MI, Stockwell PA, Black MA, Day RC, Lamont IL, Poulter RTM. Pseudomonas syringae pv. actinidiae from Recent Outbreaks of Kiwifruit Bacterial Canker Belong to Different Clones That Originated in China. Gribaldo S, ed. PLoS ONE. 2013;8(2):e57464. DOI: 10.1371/journal.pone.0057464.

Contact
margi.butler@otago.ac.nz
Tn6213
Dr Margi Butler
University of Otago
Characteristics
Tn6213 is a 4.8-kb transposon, which is homologous element in Pseudomonas syringae pv. avellanae, with ∼99% sequence identity to Tn6211.
References

Butler MI, Stockwell PA, Black MA, Day RC, Lamont IL, Poulter RTM. Pseudomonas syringae pv. actinidiae from Recent Outbreaks of Kiwifruit Bacterial Canker Belong to Different Clones That Originated in China. Gribaldo S, ed. PLoS ONE. 2013;8(2):e57464. DOI: 10.1371/journal.pone.0057464.

Contact
margi.butler@otago.ac.nz
Tn6214
Dr Michael Mulvey
Public Health Agency of Canada
  • Antibiotic Resistance
  • Amikacin
  • Ampicillin
  • Carbapenem
  • Chloramphenicol
  • Gentamicin
  • Kanamycin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn6214 is a 29-kb complex transposon found in plasmid pG5A4Y217 from Escherichia coli strain A4Y217. It composed of In4-like [containing IS6100, IS26, sul1 gene in 3'CS of the integron, blaOXA-2, aadA5, aadB and blaTEM-1 in gene cassette array], a dericative of Tn9 [containing catA1 gene], a Tn21-like element [containing mercury resistance gene cluster (merRTPCADE) and In2-like element (containing IS1353, IS1326, sul1 gene in 3'CS of integron and aacA4 and blaGES-5 in the gene cassette array)].
References

Boyd, D., et al. (2015). "Complete Sequence of Four Multidrug-Resistant MOBQ1 Plasmids Harboring blaGES-5 Isolated from Escherichia coli and Serratia marcescens Persisting in a Hospital in Canada." Microb Drug Resist 21(3): 253-260. DOI: 10.1089/mdr.2014.0205

Accession number
Contact
michael.mulvey@phac-aspc.gc.ca
Tn6215
Dr Shan Goh
Royal Veterinary College
  • Antibiotic Resistance
  • Erythromycin
Characteristics
Tn6215 is a 13-kb transposon, found in Clostridioides difficile strain CD80. It contained 17 ORFs, encoding proteins for recombination (a putative serine site-specific recombinase and toposiomerase), mobilization and replication (TnpZ and RepA_N), stability (Xre antitoxin, acetyltransferase and the ω-ε-ζ system) and erythromycin resistance (erm(B)).
References

Goh S, Hussain H, Chang BJ, Emmett W, Riley TV, Mullany P. Phage ϕC2 Mediates Transduction of Tn6215, Encoding Erythromycin Resistance, between Clostridium difficile Strains. mBio. 2013;4(6):e00840-13. DOI: 10.1128/mBio.00840-13.

Accession number
Contact
sgoh@rvc.ac.uk
Tn6216
Dr Andreas Friedrich Wendel
Institute of medical microbiology
  • Antibiotic Resistance
  • Carbapenem
  • Kanamycin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6216 is a 14-kb transposon on a 25-kb plasmid from Enterobacter cloacae strain M15. It contained Tn402-like transposon inserted into Tn21-like transposon [containing IS6100 and class 1 integron with resistance genes: blaGIM-1, aacA4, aadA1, blaOXA-2, qacEΔ1, and sul1].
References

Wendel AF, Kaase M, Autenrieth IB, et al. Protracted Regional Dissemination of GIM-1-Producing Serratia marcescens in Western Germany. Antimicrobial Agents and Chemotherapy. 2017;61(3):e01880-16. DOI: 10.1128/AAC.01880-16.

Accession number
Contact
andreas.wendel@med.uni-duesseldorf.de
Tn6217
Prof Paul Roy
Université Laval
  • Antibiotic Resistance
  • Carbenicillin
  • Chloramphenicol
  • Kanamycin
  • Sulphonamide
Characteristics
Tn6217 is a 6.9-kb transposon, found on plasmid pOZ176 from Pseudomonas aeruginosa strain PA96. It contained a class 1 integron [carried three cassettes (aacA4→catB8a→blaOXA-10), sul1-type 3′-CS and an IS6100]
References

Xiong J, Alexander DC, Ma JH, et al. Complete Sequence of pOZ176, a 500-Kilobase IncP-2 Plasmid Encoding IMP-9-Mediated Carbapenem Resistance, from Outbreak Isolate Pseudomonas aeruginosa 96. Antimicrobial Agents and Chemotherapy. 2013;57(8):3775-3782. DOI: 10.1128/AAC.00423-13.

Accession number
Contact
paul.roy@crchul.ulaval.ca
Tn6218
Dr Kate Dingle
Oxford University
  • Antibiotic Resistance
  • Chloramphenicol
  • Erythromycin
  • Fluoroquinolone
  • Gentamicin
  • Kanamycin
  • Streptogramin A
Characteristics
Tn6218 is a 14.2-kb Tn916-related transposon, but nonconjugative, found in Clostridium difficile. Several resistance genes were found in this transposon, including erm(B), cfr (Chloramphenicol/fluorfenicol resistance protein), matE (multidrug and toxic compound extrusion (MATE)-like proteins) and aacA-aphD genes.
References

Dingle KE, Elliott B, Robinson E, et al. Evolutionary History of the Clostridium difficile Pathogenicity Locus. Genome Biology and Evolution. 2014;6(1):36-52. DOI: 10.1093/gbe/evt204.

Accession number
Contact
kate.dingle@ndcls.ox.ac.uk
Tn6219
Dr Rémy Bonnin
Service de bactériologie, INSERM U914
Contact
remy.bonnin@u-psud.fr
Tn6220
Dr VINCENZO DI PILATO
UNIVERSITY OF SIENA
Contact
vdipilato@unisi.it
Tn6221
Mr Miguel Vaz
University of Porto
Contact
mjsvaz@gmail.com
Tn6222
Dr Piklu Roy Chowdhury
the i3 institute, Faculty of Science
  • Antibiotic Resistance
  • Ampicillin
  • Trimethoprim
Characteristics
Tn6222 is a 7.8-kb composite transposon found in Escherichia coli O104:H4 strain 2009EL-2050. It comprised of three IS26 elements, flanking a class 1 integron [containing a dfrA7 gene cassette] and blaTEM-1 gene.
References

Chowdhury PR, Charles IG, Djordjevic SP. A Role for Tn6029 in the Evolution of the Complex Antibiotic Resistance Gene Loci in Genomic Island 3 in Enteroaggregative Hemorrhagic Escherichia coli O104:H4. van Schaik W, ed. PLoS ONE. 2015;10(2):e0115781. DOI: 10.1371/journal.pone.0115781.

Accession number
Contact
piklu.bhattacharya@uts.edu.au
Tn6223
Dr Piklu Roy Chowdhury
the i3 institute, Faculty of Science
Characteristics
Tn6223 is a 1.5-kb composite transposon found in Escherichia coli O104:H4 strain 2011C-3493. It was related to Tn6029C, with the insertion of IS26 and deletion of blaTEM-1.
References

Chowdhury PR, Charles IG, Djordjevic SP. A Role for Tn6029 in the Evolution of the Complex Antibiotic Resistance Gene Loci in Genomic Island 3 in Enteroaggregative Hemorrhagic Escherichia coli O104:H4. van Schaik W, ed. PLoS ONE. 2015;10(2):e0115781. DOI: 10.1371/journal.pone.0115781.

Accession number
Contact
piklu.bhattacharya@uts.edu.au
Tn6224
Miss Emma Raftis
University College Cork
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6224 is an integrated conjugative transposon, found in plasmid pCTN1046 from Lactobacillus salivarius strain JCM1046. It was similar to the conjugative element Tn916, including tet(M), and lacks only two genes, which encode hypothetical proteins in the conjugative region of Tn916.
References

Raftis EJ, Forde BM, Claesson MJ, O’Toole PW. Unusual genome complexity in Lactobacillus salivarius JCM1046. BMC Genomics. 2014;15(1):771. DOI: 10.1186/1471-2164-15-771.

Accession number
Contact
emmaraftis@gmail.com
Tn6225
Dr Francesco Santoro
University of Siena
Contact
santorof@unisi.it
Tn6226
Dr Francesco Santoro
University of Siena
Contact
santorof@unisi.it

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