The Transposon Registry

Displaying 381 - 400 of 2138
Tn6067
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6068
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6069
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6070
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6071
Dr Michael Ryan
University of Limerick
Contact
uler12@yahoo.com
Tn6072
Dr Liang Chen
PHRI-NJMS, UMDNJ
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn6072 is a 29.4-kb composite transposon in methicillin-resistant Staphylococcus aureus ST239, containing IS431 flanking 29 ORFs. It is homologous staphylococcal cassette chromosome mercury (SCCHg) but lacks the characteristic mer operon. It contains Tn554 which was disrupted by the insertion of IS4001 (containing aacA kanamycin resistance gene).
References

Chen L, Mediavilla JR, Smyth DS, et al. Identification of a Novel Transposon (Tn6072) and a Truncated Staphylococcal Cassette Chromosome mecElement in Methicillin-Resistant Staphylococcus aureus ST239 . Antimicrobial Agents and Chemotherapy. 2010;54(8):3347-3354. DOI: 10.1128/AAC.00001-10.

Accession number
Contact
chen11@umdnj.edu
Tn6073
Mr Michael Brouwer
UCL Eastman Dental Institute
  • Efflux functions
Characteristics
Tn6073 is a 29.1-kb transposon found in Clostridium difficile strain QCD-23M63. The accessory module of the element consists of genes encoding a predicted N-terminal hydrolase, a sigma factor and an ABC transporter.
References

Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E. Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile . Highlander SK, ed. PLoS ONE. 2011;6(8):e23014. DOI: 10.1371/journal.pone.0023014.

Accession number
Contact
m.brouwer@ucl.ac.uk
Tn6074
Dr Helena Seth-Smith
Wellcome Trust Sanger Insitute
  • Antibiotic Resistance
  • Bleomycin
  • Quinalone
  • Efflux functions
Characteristics
Tn6074 (also called ICE6074 and ICESb1) is a 109-kb transposon found in Salmonella bongori strain CEIM46082. It contains genes encoding putative mobility functions (replication, type IVB pilus, transfer/conjugation, and integration/excision) and also genes encoding a putative autotransporter, ion channel, quinolone resistance, bleomycin resistance and drug efflux. However, no increase in resistance to bleomycin, nalidixic acid, ciprofloxacin, marbofloxacin, or enrofloxacin was seen in the host strains of ICESb1, indicating that these CDSs may not be expressed under the conditions tested or that they have alternative functions.
References

Seth-Smith HMB, Fookes MC, Okoro CK, et al. Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae. Journal of Bacteriology. 2012;194(6):1494-1504. DOI: 10.1128/JB.06403-11.

Accession number
Contact
hss@sanger.ac.uk
Tn6075
Dr Helena Seth-Smith
Wellcome Trust Sanger Insitute
Characteristics
Tn6075 (also called ICE6075 and ICESe3) is a 104-kb ICE found in Salmonella subgroup VII strain CDC5039-68. It contained genes encoding putative mobility functions (replication, type IVB pilus, transfer/conjugation, and integration/excision) and also genes involving in adhesion (EtpAB) and fimbrial operon.
References

Seth-Smith HMB, Fookes MC, Okoro CK, et al. Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae. Journal of Bacteriology. 2012;194(6):1494-1504. DOI: 10.1128/JB.06403-11.

Accession number
Contact
hss@sanger.ac.uk
Tn6076
Dr Helena Seth-Smith
Wellcome Trust Sanger Insitute
  • Metabolism
  • Sucrose metabolism
Characteristics
Tn6076 (also called ICE6076 and CTnscr94) is a 114-kb conjugative transposon found in Salmonella Senftenberg strain 5494-57. It contained genes encoding putative mobility functions (replication, type IVB pilus, transfer/conjugation, and integration/excision) and also genes involving in adhesion (CdiAB), Restriction-modification system, Methyl-accepting chemotaxis and sucrose metabolism.
References

Seth-Smith HMB, Fookes MC, Okoro CK, et al. Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae. Journal of Bacteriology. 2012;194(6):1494-1504. DOI: 10.1128/JB.06403-11.

Accession number
Contact
hss@sanger.ac.uk
Tn6077
Dr Helena Seth-Smith
Wellcome Trust Sanger Insitute
  • Efflux functions
Characteristics
Tn6077 (also called ICE6077 and ICEYe1) is a 120-kb ICE found in Yersinia enterocolitica strain Y69. It contained genes encoding putative mobility functions (replication, type IVB pilus, transfer/conjugation, and integration/excision) and also genes involving in Type 6 secretion system, Fimbrial operon and Drug efflux.
References

Seth-Smith HMB, Fookes MC, Okoro CK, et al. Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae. Journal of Bacteriology. 2012;194(6):1494-1504. DOI: 10.1128/JB.06403-11.

Accession number
Contact
hss@sanger.ac.uk
Tn6078
Dr Robinson D. Ashley
University of Mississippi Medical Center
Contact
darobinson@microbio.umsmed.edu
Tn6079
Miss Lisbeth Elvira de Vries
National Food Institute, DTU
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn6079 is a 28.4-kb Tn916-like conjugative transposon, found in infant GI metagenomic library. It was highly similar to a putative Tn916-like transposon identified in Streptococcus gallolyticus subsp. gallolyticus strain UCN34, carrying tetracycline resistance genes tet(M) and tet(L), with the insertion of erythromycin resistance gene erm(T) [flanking by two putative IS1216 elements].
References

De Vries LE, Vallès Y, Agersø Y, et al. The Gut as Reservoir of Antibiotic Resistance: Microbial Diversity of Tetracycline Resistance in Mother and Infant. Gilbert JA, ed. PLoS ONE. 2011;6(6):e21644. DOI: 10.1371/journal.pone.0021644.

Accession number
Contact
ledv@life.ku.dk
Tn6080
Dr Te-Li Chen
Taipei Veterans General Hospital
  • Antibiotic Resistance
  • Imipenem
  • Meropenem
Characteristics
Tn6080 is a 3.2-kb transposon found on the plasmid in Acinetobacter baumannii Isolates in Taiwan. It contained ISAba1, blaOXA-51-like (blaOXA-82), srt (sortase), orf14 (transcriptional regulator).
References

Chen T-L, Lee Y-T, Kuo S-C, et al. Emergence and Distribution of Plasmids Bearing the blaOXA-51-Like Gene with an Upstream ISAba1 in Carbapenem-Resistant Acinetobacter baumannii Isolates in Taiwan. Antimicrobial Agents and Chemotherapy. 2010;54(11):4575-4581. DOI: 10.1128/AAC.00764-10.

Accession number
Contact
tlchen@vghtpe.gov.tw
Tn6081
Dr Te-Li Chen
Taipei Veterans General Hospital
Contact
tlchen@vghtpe.gov.tw
Tn6082
Dr Teruya Komano
Tokyo Metropolitan University
  • Antibiotic Resistance
  • Streptomycin
Characteristics
Tn6082 is a 3.6-kb transposon found in plasmid R64 from Salmonella enterica serovar Typhimurium. It carried tnpA, strA and strB genes. Analysis of nucleotide sequences revealed that IS1133 was inserted into Tn6082 and finally, Tn10 was inserted into IS1133 in plasmid R64.
References

Sampei, G., et al. (2010). "Complete genome sequence of the incompatibility group I1 plasmid R64." Plasmid 64(2): 92-103. DOI: 10.1016/j.plasmid.2010.05.005

Accession number
Contact
komano-teruya@c.metro-u.ac.jp
Tn6083
Dr Helena Seth-Smith
Wellcome Trust Sanger Insitute
  • Antibiotic Resistance
  • Bleomycin
  • Quinalone
Characteristics
Tn6083 (also called ICE6083 and ICEsb2) is an 84-kb ICE found in Salmonella bongori strain 2022/77. It contained genes encoding putative mobility functions (replication, type IVB pilus, transfer/conjugation, and integration/excision), and also genes encoding acetyltransferase, MipA domain protein, quinolone resistance, bleomycin resistance, dienelactone hydrolase, immunoglobuline binding regulators IbrAB and AraC-family regulator. However, no increase in resistance to bleomycin, nalidixic acid, ciprofloxacin, marbofloxacin, or enrofloxacin was seen in the host strains of ICESb2, indicating that they may not be expressed under the conditions tested or that they have alternative functions.
References

Seth-Smith HMB, Fookes MC, Okoro CK, et al. Structure, Diversity, and Mobility of the Salmonella Pathogenicity Island 7 Family of Integrative and Conjugative Elements within Enterobacteriaceae. Journal of Bacteriology. 2012;194(6):1494-1504. DOI: 10.1128/JB.06403-11.

Accession number
Contact
hss@sanger.ac.uk
Tn6084
Dr Louis B. Rice
Louis Stokes Cleveland VA Medical Center
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6084 is a 22.3-kb Tn916-like transposon, found in Enterococcus faecium C68. It contained an insertion of a 2.7-kb putative group II intron at Tn916_06 (formerly orf19) and an insertion of ISEfa11 upstream of tet(M).
References

Rice LB, Carias LL, Rudin S, Hutton RA, Marshall S. Multiple copies of functional, Tet(M)-encoding Tn916-like elements in a clinical Enterococcus faecium isolate. Plasmid. 2010;64(3):150-155. DOI: 10.1016/j.plasmid.2010.06.003.

Accession number
Contact
louis.rice@med.va.gov
Tn6085
Dr Louis B. Rice
Louis Stokes Cleveland VA Medical Center
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6085 is a 20.8-kb Tn916-like transposon, found in Enterococcus faecium C68. It contained an insertion of a 2.7-kb putative group II intron at Tn916_06 (formerly orf19).
References

Rice LB, Carias LL, Rudin S, Hutton RA, Marshall S. Multiple copies of functional, Tet(M)-encoding Tn916-like elements in a clinical Enterococcus faecium isolate. Plasmid. 2010;64(3):150-155. DOI: 10.1016/j.plasmid.2010.06.003.

Accession number
Contact
louis.rice@med.va.gov
Tn6086
Dr Louis B. Rice
Louis Stokes Cleveland VA Medical Center
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6086 is a 24.5-kb conjugative transposon isolated from Enterococcus faecium strain TC 6, which contained tetM tetracycline resistance gene.
References
Carias,L.L. and Rice,L.B. (Unpublished)
Accession number
Contact
louis.rice@med.va.gov

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