Tn registry

Displaying 81 - 100 of 652
Tn1549
  • Antibiotic Resistance
  • Vancomycin
Characteristics
Tn1549 is a 34 kb conjugative transposon harbouring a vanB operon. Tn 1549 is highly similar to Tn5382 and together they are called Tn1549-like transposons. Tn1549 contains 30 ORFs which are generally organized like the Tn916 family of conjugative transposons in which the vanB2 operon replaces the tet(M) gene.
References

Garnier, F., Taourit, S., Glaser, P., Courvalin, P., & Galimand, M. (2000). Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp. Microbiology146(6), 1481-1489. doi: 10.1099/00221287-146-6-1481

Launay, A., Ballard, S. A., Johnson, P. D., Grayson, M. L., & Lambert, T. (2006). Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic mice.Antimicrobial agents and chemotherapy50(3), 1054-1062. doi: 10.1128/AAC.50.3.1054-1062.2006

Accession number
Tn1681
  • Virulence Determinants
  • Toxin production
Characteristics
Tn1681 is a composite transposon identified from enterotoxigenic Escherichia coli strains. It carries gene encoding for heat-stable toxin (ST I), which is flanked by inverted repeats of IS1.
References

So, M., & McCarthy, B. J. (1980). Nucleotide sequence of the bacterial transposon Tn1681 encoding a heat-stable (ST) toxin and its identification in enterotoxigenic Escherichia coli strains. Proceedings of the National Academy of Sciences of the United States of America77(7), 4011–4015. PMID: 6254008

Accession number
Tn1696
  • Antibiotic Resistance
  • Chloramphenicol
  • Gentamicin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn1696 is a 13.6 kb transposon, found on plasmid R1036 from Pseudomonas aeruginosa strain. It carries a class 1 integron In4 (8.33kb), which contains four gene cassettes (aacC1, orfE, aadA2, and cmlA1) and sul1 gene. The In4 integron located within the res region of the transposon backbone. Mercury resistance gene can also be found on the transposon backbone.
References

Partridge, S. R., Brown, H. J., Stokes, H. W., & Hall, R. M. (2001). Transposons Tn1696 and Tn21 and Their Integrons In4 and  In2 Have Independent Origins. Antimicrobial Agents and Chemotherapy45(4), 1263–1270. DOI: 10.1128/AAC.45.4.1263-1270.2001

Accession number
Tn1699
  • Antibiotic Resistance
  • Ampicillin
  • Gentamicin
  • Kanamycin
Characteristics
Tn1699 is a 9.3 kb transposon found on plasmid pCER7999, isolated from Klebsiella pneumoniae, which contains bla-TEM1 and aac(3) genes.
References

Rubens, C. E., McNeill, W. F., & Farrar, W. E. (1979). Evolution of multiple-antibiotic-resistance plasmids mediated by transposable plasmid deoxyribonucleic acid sequences. Journal of Bacteriology140(2), 713–719. PMID: 387747

 

Tn1700
  • Antibiotic Resistance
  • Ampicillin
  • Gentamicin
  • Kanamycin
Characteristics
Tn1700 is a 12 kb transposon found on plasmid pCER1065, isolated from Serratia marcescens, which contains bla-TEM1 and aad(2") genes.
References

Rubens, C. E., McNeill, W. F., & Farrar, W. E. (1979). Evolution of multiple-antibiotic-resistance plasmids mediated by transposable plasmid deoxyribonucleic acid sequences. Journal of Bacteriology140(2), 713–719. PMID: 387747

Tn1701
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn1701 is recovered from Salmonella typhimurium located on a plasmid NTP1. It contain a blaTEM-1 gene, conferring ampicillin resistance.
References

Yamada Y, et al. (1979). Location of an ampicillin resistance transposon, Tn1701, in a group of small, nontransferring plasmids. Journal of Bacteriology137(2), 990–999. PMID: 370108

Tn1720
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn1720 is a 9.3-kb variant of transposon Tn1721 (lacking orfI of Tn1721). It confers tetracycline resistance by carrying tetA gene.
References

Schnabel, E. L., & Jones, A. L. (1999). Distribution of Tetracycline Resistance Genes and Transposons among Phylloplane Bacteria in Michigan Apple Orchards. Applied and Environmental Microbiology65(11), 4898–4907. PMID: 10543801 

Tn1721
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn1721 is a 11.1 kb transposon, carrying a minitransposon Tn1722, tnpA, tccA, partial tetR and tetA genes.
References

Rhodes G, et al. (2000). Distribution of Oxytetracycline Resistance Plasmids between Aeromonads in Hospital and Aquaculture Environments: Implication of Tn1721in Dissemination of the  Tetracycline Resistance Determinant Tet A. Applied and Environmental Microbiology66(9), 3883–3890. DOI: 10.1128/AEM.66.9.3883-3890.2000

Accession number
Tn1722
Characteristics
Tn1722 is a 5.5 kb minitransposon, which can be found as a part of Tn1721. It carries orfI, res, tnpR and tnpA genes.
References

Rhodes G, et al. (2000). Distribution of Oxytetracycline Resistance Plasmids between Aeromonads in Hospital and Aquaculture Environments: Implication of Tn1721in Dissemination of the  Tetracycline Resistance Determinant Tet A. Applied and Environmental Microbiology66(9), 3883–3890. DOI: 10.1128/AEM.66.9.3883-3890.2000

Tn1723
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn1723 is a derivative of Tn3-like transposon Tn1722 with the insertion of a kanamycin resistance gene (3.9 kb).
References

Cross, M. A., et al. (1986). Analysis of the vegetative replication origin of broad-host-range plasmid RK2 by transposon mutagenesis. Plasmid 15(2): 132-146. DOI: 10.1016/0147-619X(86)90049-1

Tn1725
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn1725 is an 8.3 kb derivative of Tn1721, containing a chloramphenicol resistance gene.
References

Cram, H. K., et al. (1984). F plasmid pif region: Tn1725 mutagenesis and polypeptide analysis. Gene 32(1-2): 251-254. DOI: 10.1016/0378-1119(84)90053-2

Altenbuchner, J., Schmid, K., & Schmitt, R. (1983). Tn1721-encoded tetracycline resistance: mapping of structural and regulatory genes mediating resistance. Journal of Bacteriology153(1), 116–123. PMID: 6294046 

Tn1732
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn1732 is a Tn3-family transposon, containing kanamycin resistance gene.
References

Canovas, D., et al. (1997). Isolation and characterization of salt-sensitive mutants of the moderate halophile Halomonas elongata and cloning of the ectoine synthesis genes." J Biol Chem 272(41): 25794-25801. DOI: 10.1074/jbc.272.41.25794

Jörg Kunte, H. and E. A. Galinski (1995). Transposon mutagenesis in halophilic eubacteria: conjugal transfer and insertion of transposon Tn5 and Tn1732 in Halomonas elongata. FEMS Microbiology Letters 128(3): 293-299. DOI: 10.1111/j.1574-6968.1995.tb07539.x

Tn1755
  • Antibiotic Resistance
  • Ampicillin
  • Kanamycin
Characteristics
Tn1755 is derived from plasmid RP4::Tn1. It contains two inverted Tn1 elements (carrying ampicillin resistance gene), flanking a DNA fragment (including kanamycin resistance gene).
References

Dobritsa, A. P., et al. (1981). Transposition of a DNA fragment flanked by two inverted Tn1 sequences. Gene 14(3): 217-225. DOI: 10.1016/0378-1119(81)90117-7

Tn1756
  • Antibiotic Resistance
  • Ampicillin
  • Tetracycline
Characteristics
Tn1755 is derived from plasmid RP4::Tn1, which also contains Tn1755. It contains two inverted Tn1 elements (carrying ampicillin resistance gene), flanking a DNA fragment (including tetracycline resistance gene).
References

Dobritsa, A. P., et al. (1983). Transposition of DNA fragments flanked by two inverted Tn1 sequences: translocation of the plasmid RP4::Tn1 region harboring the Tcr marker. Gene 22(2-3): 237-243. DOI: 10.1016/0378-1119(83)90108-7

Tn1771
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn1771 is identified from Escherichia coli UR12644 with a molecular weight of 7.1 Mdal, which can confer tetracycline resistance.
References

Schoffl, F. and A. Puhler (1979). "Intramolecular amplification of the tetracycline resistance determinant of transposon Tn1771 in Escherichia coli." Genet Res 33(3): 253-260. DOI:10.1017/S0016672300018395

Tn1792
  • Antibiotic Resistance
  • Gentamicin
Characteristics
Tn1792 is a minitransposon based on IS6100, constructed for transposon mutagenesis of the Streptomyces genome. It contains aac(3)-Ia gene, conferring gentamycin resistance, for selection.
References

Herron, P. R., et al. (1999). Low target site specificity of an IS6100-based mini-transposon, Tn1792, developed for transposon mutagenesis of antibiotic-producing Streptomyces. FEMS Microbiol Lett 171(2): 215-221. DOI: 10.1111/j.1574-6968.1999.tb13435.x

Accession number
Tn1806
  • Antibiotic Resistance
  • Erythromycin
Characteristics
Tn1806 is a 52.4 kb transposon comprising 49 ORFs. It carries an erm(TR) gene that confers resistance to erythromycin and was originally identified in the chromosome of Streptococcus pneumoniae. Tn1806 shows an overall similarity with the erm(TR)-carrying genetic element described in Streptococcus pyogenes MGAS10750, named ICE10750 RD-2.
References

Camilli, R., Del Grosso, M., Iannelli, F., & Pantosti, A. (2008). New genetic element carrying the erythromycin resistance determinant erm (TR) in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy52(2), 619-625. DOI: 10.1128/AAC.01081-07

Camilli, R., Bonnal, R. J., Del Grosso, M., Iacono, M., Corti, G., Rizzi, E., ... & Oggioni, M. R. (2011). Complete genome sequence of a serotype 11A, ST62 Streptococcus pneumoniae invasive isolate. BMC microbiology11(1), 25. DOI: 10.1186/1471-2180-11-25

Accession number
Tn1822
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn1822 is a tetracylcine resistant transposon which is very similar to Tn1771 and Tn1721.
References

Tietze, E., Prager, R., & Tschäpe, H. (1982). Characterization of the transposons Tn1822 (Tc) and Tn1824 (TpSm) and the light they throw on the natural spread of resistance genes. Plasmid8(3), 253-260. DOI: 10.1016/0147-619X(82)90063-4

Tn1824
  • Antibiotic Resistance
  • Streptomycin
  • Trimethoprim
Characteristics
Tn1824 is a trimethoprim-streptomycin resistant transposon which is very similar to Tn7.
References

Tietze, E., Prager, R., & Tschäpe, H. (1982). Characterization of the transposons Tn1822 (Tc) and Tn1824 (TpSm) and the light they throw on the natural spread of resistance genes. Plasmid8(3), 253-260. DOI:10.1016/0147-619X(82)90063-4

Tn1825
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Streptothricin
Characteristics
Tn1825 is a 13.2 kb transposon related to Tn7-family transposons carrying a streptothricin resistance determinant. Tn1825 also codes for a low level streptomycin/spectinomycin resistance due to the aminoglycoside adenylyltransferase, aad(3”) gene.
References

Tietze, E., Brevet, J., & Tschäpe, H. (1987). Relationships among the streptothricin resistance transposons Tn1825 and Tn1826 and the trimethoprim resistance transposon Tn7. Plasmid, 18(3), 246-249. DOI: 10.1016/0147-619X(87)90067-9

Tschäpe, H., Tietze, E., Prager, R., Voigt, W., Wolter, E., & Seltmann, G. (1984). Plasmid-borne streptothricin resistance in gram-negative bacteria.Plasmid12(3), 189-196. DOI: 10.1016/0147-619X(84)90043-X

Pages