The Transposon Registry

Displaying 41 - 60 of 2084

Tn801

Antibiotic Resistance
Ampicillin

Characteristics

Tn801, previously called as TnA, is closely related to Tn3 and contains blaTEM-15, transposase and resolvase genes.

References

Chouchani C, et al. (2007). Cloning and sequencing of the class A beta-lactamase gene (blaTEM-15) located on a chromosomal Tn801 transposon. Diagn Microbiol Infect Dis 58(4): 459-463. doi: 10.1016/j.diagmicrobio.2007.02.012

Ward, JM, et al, (1978). Mapping of functions in the R-plasmid R388 by examination of deletion mutants generated in vitro. Gene 3(2): 87-95. doi: 10.1016/0378-1119(78)90053-7

Accession number

AF080442

Tn802

Antibiotic Resistance
Ampicillin

Characteristics

Tn802 is identified from a plasmid RP1-1. It is similar to Tn801 and contains ampicillin resistance gene.

References

Grinsted J, et al. (1978). Regional preference of insertion of Tn501 and Tn802 into RP1 and its derivatives. Mol Gen Genet 166(3): 313-320. doi: 10.1007/BF00267624

Tn804

Antibiotic Resistance
Tetracycline

Characteristics

Tn804 was found in Escherichia coli and was shown to compose of Tn10 and another transposable sequence. Tetracycline resistance gene is located with in the Tn10 part of Tn804.

References

Jørgensen ST, et al. (1980). New translocation sequence mediating tetracycline resistance found in Escherichia coli pathogenic for piglets. Antimicrobial Agents and Chemotherapy, 18(1), 200–205. doi: 10.1128/AAC.18.1.200

Tn813

Antibiotic Resistance
Spectinomycin
Streptomycin
Sulphonamide
Heavy Metal Resistance
Mercury Resistance

Characteristics

Tn813 is a tnpR mutant of Tn21, which contains mercury resistance (mer) operon, integron In2, IS1326 and IS1353.

References

Balligand G, et al. (1985). Genetic analysis of virulence plasmid from a serogroup 9 Yersinia enterocolitica strain: role of outer membrane protein P1 in resistance to human serum and autoagglutination. Infection and Immunity, 48(3), 782–786. PMID: 2987130

Diver, WP, et al. (1983). DNA sequences of and complementation by the tnpR genes of Tn21, Tn501 and Tn1721. Mol Gen Genet 191(2): 189-193. doi: 10.1007/BF00334812

Tn841

Antibiotic Resistance
Ceftazidime

Characteristics

Tn841 is approximately 7 kb in size, which contains a gene encoding TEM-12 beta-lactamase.

References

Heritage J, et al. (1992). Transposition of the gene encoding a TEM-12 extended-spectrum beta-lactamase. Antimicrobial Agents and Chemotherapy, 36(9), 1981–1986. doi: 10.1128/AAC.36.9.1981

Accession number

M88143

Tn901

Antibiotic Resistance
Ampicillin

Characteristics

Tn901 was found to be located on plasmid pRI477A of Salmonella panama. It encodes ampicillin resistance.

References

Andreoli, P. M., Overbeeke, N., Veltkamp, E., Embden, J. V., & Nijkamp, H. J. J. (1978). Genetic map of the bacteriocinogenic plasmid CLO DF13 derived by insertion of the transposon Tn901. Molecular and General Genetics MGG, 160(1), 1-11. DOI: 10.1007/BF00275113

Embden, J. D. A. (1978). Translocation of an ampicillin resistance determinant within an R-factor aggregate in Salmonella panama. Antonie Van Leeuwenhoek, 44(2), 203-218. DOI: 10.1007/BF00643223

Tn902

Antibiotic Resistance
Ampicillin

Characteristics

Tn902 is a Tn3-like transposon which carries a bla gene and confers resistance to ampicillin.

References

Iida, S., Hiestand-Nauer, R., Hänni, C., & Arber, W. (1985). Reversion of a truncated gene for ampicillin resistance by genetic rearrangements in Escherichia coli K12. Molecular and General Genetics MGG, 201(2), 174-177. DOI: 10.1007/BF00425656

Tn903

Antibiotic Resistance
Kanamycin

Characteristics

Tn903 is a kanamycin resistance transposon with a size of 3094 bp. It is identical to Tn55 and Tn601.

References

Oka, A., Sugisaki, H., & Takanami, M. (1981). Nucleotide sequence of the kanamycin resistance transposon Tn903. Journal of molecular biology,147(2), 217-226. DOI: 10.1016/0022-2836(81)90438-1

Accession number

V00359

Tn904

Antibiotic Resistance
Streptomycin

Characteristics

Tn904 is a streptomycin resistance transposon with a estimated size of 5.2 kb.

References

McCombie, W. R., Hansen, J. B., Zylstra, G. J., Maurer, B., & Olsen, R. H. (1983). Pseudomonas streptomycin resistance transposon associated with R-plasmid mobilization. Journal of Bacteriology, 155(1), 40-48. PMCID: PMC217649

Tn916

Antibiotic Resistance
Tetracycline

Characteristics

Tn916 is a conjugative transposon with a size of 18,032 bp. It was originally found in Enterococcus faecalis DS16. Tn916 was the first conjugative transposon reported to encode antibiotic resistance determinants. It confers resistance to tetracycline via tet(M).

References

Franke, A. E., & Clewell, D. B. (1981). Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of" conjugal" transfer in the absence of a conjugative plasmid. Journal of Bacteriology, 145(1), 494-502. PMCID: PMC217299

Flannagan, S. E., Zitzow, L. A., Su, Y. A., & Clewell, D. B. (1994). Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid, 32(3), 350-354. DOI: 10.1006/plas.1994.1077

Roberts, A. P., Browne, H. P., Anvar, S. Y., Frank, J., Lawley, T. D., & Smits, W. K. (2014). Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916. FEMS microbiology letters, 362(3), 1-4. DOI: 10.1093/femsle/fnu050

Accession number

Tn917

Antibiotic Resistance
Erythromycin
Lincomycin

Characteristics

Tn917 is a 5.2 kb transposon originally identified on plasmid pAD2 of Enterococcus faecalis DS16. Tn917 confers resistance to macrolide-lincosamide-streptogramin B (MLS) class antibiotics via erm(B).

References

Perkins, J. B., & Youngman, P. J. (1984). A physical and functional analysis of Tn917, a Streptococcus transposon in the Tn3 family that functions in Bacillus. Plasmid, 12(2), 119-138. DOI: 10.1016/0147-619X(84)90058-1

Shaw, J. H., & Clewell, D. B. (1985). Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis. Journal of Bacteriology, 164(2), 782-796. PMID: 2997130

Accession number

M11180

Tn918

Antibiotic Resistance
Tetracycline

Characteristics

Tn918 is a 16.8 kb conjugative transposon similar to Tn916 and was originally detected in Enterococcus faecalis RC73. It confers resistance to tetracycline via tet(M).

References

Clewell, D. B., An, F. Y., White, B. A., & Gawron-Burke, C. Y. N. T. H. I. A. (1985). Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). Journal of bacteriology, 162(3), 1212-1220. Link: http://jb.asm.org/content/162/3/1212

Tn919

Antibiotic Resistance
Tetracycline

Characteristics

Tn919 is a conjugative transposon similar to Tn916 and was originally detected in Streptococcus sanguis FC1. It carries a tet(M) gene conferring tetracycline resistance.

References

Fitzgerald, G. F., & Clewell, D. B. (1985). A conjugative transposon (Tn919) in Streptococcus sanguis. Infection and immunity, 47(2), 415-420. PMCID: PMC263185

Tn924

Antibiotic Resistance
Gentamicin

Characteristics

Tn924 is a 27 kb transposon encoding resistance to gentamicin. It was detected in the chromosome of Enterococcus faecalis.

References

Thal, L. A., Chow, J. W., Clewell, D. B., & Zervos, M. J. (1994). Tn924, a chromosome-borne transposon encoding high-level gentamicin resistance in Enterococcus faecalis. Antimicrobial agents and chemotherapy, 38(5), 1152-1156. PMCID: PMC188167

Tn925

Antibiotic Resistance
Tetracycline

Characteristics

Tn925 is a conjugative transposon which encodes tetracycline resistance determinants. Tn925 shares a significant homology to Tn916. It was originally found to be located on pCF10 plasmid of Enterococcus faecalis.

References

Christie, P. J., & Dunny, G. M. (1986). Identification of regions of the Streptococcus faecalis plasmid pCF-10 that encode antibiotic resistance and pheromone response functions. Plasmid, 15(3), 230-241. DOI: 10.1016/0147-619X(86)90041-7

Torres, O. R., Korman, R. Z., Zahler, S. A., & Dunny, G. M. (1991). The conjugative transposon Tn925: enhancement of conjugal transfer by tetracycline in Enterococcus faecalis and mobilization of chromosomal genes in Bacillus subtilis and E. faecalis. Molecular and General Genetics MGG, 225(3), 395-400. Link: https://link.springer.com/article/10.1007%2FBF00261679?LI=true

Showsh, S. A., & Andrews Jr, R. E. (1996). Functional Comparison of Conjugative Transposons Tn916and Tn925. Plasmid, 35(3), 164-173. DOI: 10.1006/plas.1996.0019

Accession number

AY855841

Tn950

Antibiotic Resistance
Erythromycin

Characteristics

Tn950 is a erythromycin resistance conjugative transposon with a size of 47.0 kb. It was detected in Enterococcus faecium.

References

Takeuchi, K., Tomita, H., Fujimoto, S., Kudo, M., Kuwano, H., & Ike, Y. (2005). Drug resistance of Enterococcus faecium clinical isolates and the conjugative transfer of gentamicin and erythromycin resistance traits. FEMS microbiology letters, 243(2), 347-354. DOI: 10.1016/j.femsle.2004.12.022

Tn951

Metabolism
Lactose fermentation

Characteristics

Tn951, a lactose fermentation transposon, is 16.6 kb long and was originally found on plasmid pGC1 of Yersinia enterocolitica. It carries a lac operon.

References

Cornelis, G., Ghosal, D., & Saedler, H. (1978). Tn951: a new transposon carrying a lactose operon. Molecular and General Genetics MGG, 160(2), 215-224. DOI: 10.1007/BF00267484

Tn981

Antibiotic Resistance
Chloramphenicol

Characteristics

Tn981 is a small transposon with a size of 2.3 kb which encodes resistance to chloramphenicol.

References

Reif, H. J. (1980). Genetic evidence for absence of transposition functions from the internal part of Tn981 a relative of Tn9. Molecular and General Genetics MGG, 177(4), 667-674. DOI: 10.1007/BF00272678

Tn1000

Characteristics

Tn1000 is a 5.9 kb transposon, also known a gamma delta that belongs to the Tn3 class of transposons. It was originally identified on the F plasmid of Escherichia coli K-12.

References

Centola, M. B., Tsai, M. M., & Deonier, R. C. (1987). Transposition of Tn1000: activity of single or directly repeated termini. Journal of bacteriology, 169(12), 5852-5855. PMCID: PMC214186

Broom, J. E., Hill, D. F., Hughes, G., Jones, W. A., McNaughton, J. C., Stockwell, P. A., & Petersen, G. B. (1995). Sequence of a transposon identified as Tn1000 (γδ). DNA Sequence, 5(3), 185-189. DOI: 10.3109/10425179509029361

Accession number

X60200

Tn1005

Characteristics

Tn1005 is an artificial transposon construct carrying the wild-type Tn1000 termini and approximately 1 kb of flanking Tn1000 DNA at each end.

References

Tsai, M. M., Wong, R. Y., Hoang, A. T., & Deonier, R. C. (1987). Transposition of Tn1000: in vivo properties. Journal of bacteriology, 169(12), 5556-5562. PMCID: PMC213985

The Transposon Registry

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