Tn registry

Displaying 141 - 160 of 623
Tn2602
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn2602 is a 4.7-kb transposon, similar to Tn3 and Tn2601, which is located on plasmids Rms212. It contains blaTEM-1 gene, conferring ampicillin resistance.
References

Yamamoto, T., et al. (1980). Gene expression of ampicillin resistance transposons, Tn2601 and Tn2602. Microbiol Immunol 24(6): 479-494. DOI: 10.1111/j.1348-0421.1980.tb02852.x

Tn2603
  • Antibiotic Resistance
  • Ampicillin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2603 is approximately 20-kb transposon, carried by R plasmid RGN238. It contains genes, conferring ampicillin, streptomycin, sulfonamide, and mercury.
References

Yamamoto, T., et al. (1981). Physical and functional mapping of Tn2603, a transposon encoding ampicillin, streptomycin, sulfonamide, and mercury resistance. Mol Gen Genet 181(4): 464-469. PMID: 6267420

Tn2607
  • Antibiotic Resistance
  • Ampicillin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn2607 is a 24-kb transposon, which is generated by the transposition of Tn2601 into mercury operon on Tn21. It is found on a conjugative plasmid RGN14 and contains genes conferring streptomycin, sulfonamide, and ampicillin resistance.
References

Tanaka, M., Yamamoto, T., & Sawai, T. (1983). Evolution of complex resistance transposons from an ancestral mercury transposon. Journal of Bacteriology153(3), 1432–1438. PMID: 6298184 

Tn2608
  • Antibiotic Resistance
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2608 is a 13.5-kb transposon, found on a conjugative plasmid RGN823. It is related to a mercury transposon Tn2613 with an insertion of DNA containing streptomycin and sulfonamide resistance genes.
References

Tanaka, M., Yamamoto, T., & Sawai, T. (1983). Evolution of complex resistance transposons from an ancestral mercury transposon. Journal of Bacteriology153(3), 1432–1438. PMID: 6298184

Tn2610
  • Antibiotic Resistance
  • Ampicillin
  • Streptomycin
  • Sulphonamide
Characteristics
Tn2610 is a 23.9-kb transposon found in a conjugative plasmid pCS200 from Escherichia coli. It is composed of two transposition modules: a Tn1721-like module and a Tn21-derived module. Multiple integron-associated resistance genes (pse-1, aadA2, and sul1 genes) is located in a Tn21 backbone.
References

Takaya, A., Watanabe, M., & Yamamoto, T. (2006). Organization of Tn2610Containing Two Transposition Modules. Antimicrobial Agents and Chemotherapy50(4), 1143–1147. DOI: 10.1128/AAC.50.4.1143-1147.2006

Yamamoto, T., et al. (1983). Tn2610, a transposon involved in the spread of the carbenicillin-hydrolyzing beta-lactamase gene. Mol Gen Genet 189(2): 282-288. PMID: 6304468

Accession number
Tn2613
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2613 is a 7.2-kb transposon, found on plasmid pCS229 and conferring mercury resistance.
References

Tanaka, M., Yamamoto, T., & Sawai, T. (1983). Evolution of complex resistance transposons from an ancestral mercury transposon. Journal of Bacteriology153(3), 1432–1438. PMID: 6298184 

Tn2653
  • Antibiotic Resistance
  • Chloramphenicol
  • Tetracycline
Characteristics
Tn2653 is a 5.9-kb composite transposon, containing inverted repeats of IS1 elements. It carries two inverted repeats chloramphenicol acetyltransferase (cat) genes and one copy of tetracycline resistance gene.
References

Iida, S., Kulka, I., Meyer, J., & Arber, W. (1987). Amplification of drug resistance genes flanked by inversely repeated IS1 elements: involvement of IS1-promoted DNA rearrangements before amplification. Journal of Bacteriology169(4), 1447–1453. DOI: 10.1128/jb.169.4.1447-1453.1987

Tn2657
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn2657 is designated to the segment of (partial IS1)-pBR322-(partial IS1). It is generated by the insertion of pBR322 at the PstI site, which splits an IS1 element into two parts.
References

Iida, S., et al. (1981). Cointegrates between bacteriophage P1 DNA and plasmid pBR322 derivatives suggest molecular mechanisms for P1-mediated transduction of small plasmids. Mol Gen Genet 184(1): 1-10. PMID: 6278242

Tn2660
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn2660 is found on plasmid R6K from Escherichia coli. It contains blaTEM-1 gene, conferring ampicillin resistance.
References

Chiang, S. J., & Clowes, R. C. (1980). Intramolecular transposition and inversion in plasmid R6K. Journal of Bacteriology142(2), 668–682. PMID: 6247328 

Tn2670
  • Antibiotic Resistance
  • Chloramphenicol
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2670 is resistance determinant (r-det) located on plasmid R100-1. It composes of a Tn9-like transposon (containing the catA1 chloramphenicol resistance gene) and a transposon Tn21 (containing mer21, sul1 and aadA1 resistance genes).
References

Partridge, S. R., & Hall, R. M. (2004). Complex Multiple Antibiotic and Mercury Resistance Region Derived from the r-det of NR1 (R100). Antimicrobial Agents and Chemotherapy48(11), 4250–4255. DOI: 10.1128/AAC.48.11.4250-4255.2004

Womble, D. D., & Rownd, R. H. (1988). Genetic and physical map of plasmid NR1: comparison with other IncFII antibiotic resistance plasmids. Microbiological Reviews52(4), 433–451. PMID: 3070319

Accession number
Tn2671
  • Antibiotic Resistance
  • Chloramphenicol
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2671 is a 23-kb-transposon, located on plasmid NR1. It is a derivative of Tn2670 with an insertion of IS30 element (1.25 kb).
References

Iida, S., et al. (1981). Is the IS1-flanked r-determinant of the R plasmid NR1 a transposon? J Gen Microbiol 126(2): 413-425. DOI: 10.1099/00221287-126-2-413

Accession number
Tn2672
  • Antibiotic Resistance
  • Chloramphenicol
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2672 is a 28-kb transposon, which is a result of the transposition of Tn2671 into the ampicillin resistance gene bla of Tn902 (Tn902 bla::Tn 2671). .
References

Hänni, C., Meyer, J., Iida, S., & Arber, W. (1982). Occurrence and properties of composite transposon Tn2672: evolution of multiple drug resistance transposons. Journal of Bacteriology150(3), 1266–1273. PMID: 6281241 

Tn2680
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn2680 is a 4.95-kb transposon, which is homologous to Tn6. It is located on plasmid Rts1 and contains a gene, encoding type I aminoglycoside-3'-phosphotransferase, which is flanked by two IS26 and one IS903.B.
References

Mollet, B., Clerget, M., Meyer, J., & Iida, S. (1985). Organization of the Tn6-related kanamycin resistance transposon Tn2680 carrying two copies of IS26 and an IS903 variant, IS903. B. Journal of Bacteriology163(1), 55–60. PMID: 2989253

Tn2681
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn2681 is generated from Tn2680 by IS903.B-mediated cointegration and subsequent reciprocal recombination between the directly repeated IS26 elements, which results in two copies of IS930.B flanking a single copy of IS26 and kanamycin resistance gene.
References

Mollet, B., Clerget, M., Meyer, J., & Iida, S. (1985). Organization of the Tn6-related kanamycin resistance transposon Tn2680 carrying two copies of IS26 and an IS903 variant, IS903. B. Journal of Bacteriology163(1), 55–60. PMID: 2989253 

Tn2700
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn2700 is a composite transposon, containing direct repeats of IS30 elements flanking a chloramphenicol resistance gene.
References

Casadesus, J., et al. (1999). "Lack of hotspot targets: a constraint for IS30 transposition in Salmonella." Gene 238(1): 231-239. DOI: 10.1016/S0378-1119(99)00256-5

Tn2901
Characteristics
Tn2901 is a 11.0 kb transposon flanked by directly repeated IS1 sequences. It carries an argF gene that encodes an ornithine carbamoyltransferase subunit F.
References

York, M. K., & Stodolsky, M. (1981). Characterization of P1argF derivatives from Escherichia coli K12 transduction. Molecular and General Genetics MGG181(2), 230-240. DOI: https://link.springer.com/article/10.1007/BF00268431

Tn2921
  • Antibiotic Resistance
Characteristics
Tn2921 is a 12.4 kb transposon encoding resistance to fosfomycin. It was originally detected in plasmid pOU900 of Serratia marcescens.
References

Garcia-Lobo, J. M., & Ortiz, J. M. (1982). Tn2921, a transposon encoding fosfomycin resistance. Journal of Bacteriology151(1), 477-479. LINK:http://jb.asm.org/content/151/1/477.full.pdf

Seoane, A., Sangari, F. J., & Lobo, J. M. G. (2010). Complete nucleotide sequence of the fosfomycin resistance transposon Tn2921. International Journal of Antimicrobial Agents35(4), 413-414. DOI: https://doi.org/10.1016/j.ijantimicag.2009.12.006

 

Accession number
Tn2922
  • Antibiotic Resistance
  • Ampicillin
  • Gentamicin
Characteristics
Tn2922 is a 27 kb transposon carrying determinants of ampicillin (blaTEM) and gentamicin resistance (aacC5). It is flanked by directly oriented copies of an IS closely related to IS26.
References

Martin, C., Gomez-Lus, R., Ortiz, J. M., & Garcia-Lobo, J. M. (1987). Structure and mobilization of an ampicillin and gentamicin resistance determinant. Antimicrobial Agents and Chemotherapy31(8), 1266-1270. PMCID: PMC174916

Tn3000
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn3000 is a 11.8 kb long transposon which is bracketed by two copies of IS3000. It carries a blaNDM-1 gene. The Tn3000 has been attributed to world-wide dissemination of blaNDM-1 among Enterobacteriaceae.
References

Campos, J. C., da Silva, M. J. F., dos Santos, P. R. N., Barros, E. M., de Oliveira Pereira, M., Seco, B. M. S., ... & Cerdeira, L. T. (2015). Characterization of Tn3000, a transposon responsible for blaNDM-1 dissemination among Enterobacteriaceae in Brazil, Nepal, Morocco, and India. Antimicrobial Agents and Chemotherapy59(12), 7387-7395. DOI: 10.1128/AAC.01458-15

Tn3351
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn3351 is a chloramphenicol resistant transposon which was originally identified in the R plasmid from Salmonella naestved AHI-21 and Escherichia coli AHI-1.
References

Terakado, N. O. B. U. Y. U. K. I., Sekizaki, T., Hashimoto, K., Yamagata, S., & Yamamoto, T. (1981). Chloramphenicol transposons found in Salmonella naestved and Escherichia coli of domestic animal origin. Antimicrobial Agents and Chemotherapy20(3), 382-386. PMCID: PMC181705

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