Tn registry

Displaying 1 - 20 of 652
Tn1
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Contains bla gene encoding amp resistance. Now classed as a Tn3-like transposon.
References

Hedges, RW and Jacob, AE (1974) Transposition of ampicillin resistance from RP4 to other replicons. Mol. Gen. Genet. 132 31-40. doi:10.1007/BF00268228

Accession number
Tn2
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Transferable TEM beta-lactamase gene present on the small plasmid RSF 1030 (R-Amp)
References

Heffron, F et al. (1975) Origin of the TEM-beta-lactamase gene found on plasmids. J. Bacteriol. 122 250-6. PMID: 1091625

Partridge SR (2015) What's in a Name? ISSwi1 Corresponds to Transposons Related to Tn2 and Tn3. MBio. 6(5):e01344-15. DOI: 10.1128/mBio.01344-15

Accession number
Tn3
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn3 is a 4957bp transposon encoding three proteins: β-lactamase, an enzyme that confers resistance to β-lactam antibiotics, a transposase (encoded by gene tnpA) and a resolvase (encoded by gene tnpR)
References

P J Kretschmer and S N Cohen 1977 Selected translocation of plasmid genes: frequency and regional specificity of translocation of the Tn3 element. J. Bacteriol 130(2): 888–899. PMCID: PMC235295

R Gill, F Heffron, G Dougan, S Falkow 1978 Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3. J Bacteriol. 136(2): 742–756. PMCID: PMC218601
 
T Takeya, H Nomiyama, J Miyoshi, K Shimada, Y Takagi 1979 DNA sequences of the integration sites and inverted repeated structure of transposon Tn3. Nucleic Acids Res. 6(5): 1831–1841. PMCID: PMC327814
 
J Chou, M J Casadaban, P G Lemaux, S N Cohen 1979 Identification and characterization of a self-regulated repressor of translocation of the Tn3 element. Proc Natl Acad Sci U S A. 76(8): 4020–4024. PMCID: PMC383968
 
Accession number
Tn4
  • Antibiotic Resistance
  • Spectinomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Mercury, sulphonamide and spectinomycin resistance encoding transposon
References

D R Hyde and C P Tu 1982 Insertion sites and the terminal nucleotide sequences of the Tn4 transposon. Nucleic Acids Research 10(13): 3981–3993 PMCID: PMC320772

Accession number
Tn5
  • Antibiotic Resistance
  • Bleomycin
  • Neomycin
  • Streptomycin
Characteristics
Escherichia coli transposon (approx 5.8 kb) carrying three resistance genes
References

Berg, DE et al. (1984) Bacterial transposon Tn5: evolutionary inferences. Mol. Biol. Evol. 1 411-22  PMID: 6100989

Reznikoff, WS (2003) Tn5 as a model for understanding DNA transposition. Mol. Microbiol. 47 1199-206 PMID: 12603728

Reznikoff, WS (1993) The Tn5 transposon. Annu. Rev. Microbiol. 47 945-63 DOI: 10.1146/annurev.mi.47.100193.004501

Genilloud, O et al. (1984) The transposon Tn5 carries a bleomycin-resistance determinant. Gene 32 225-33 PMID: 6085062

Auerswald, EA et al. (1981) Structural analysis of Tn5. Cold Spring Harb. Symp. Quant. Biol. 45 Pt 1 107-13 PMID: 6271452

Accession number
Tn6
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn6 is a 4.95 kb transposon, carrying kanamycin resistance gene, which is identical to Tn2680.
References

Berg DE, et al. (1975) Transposition of R factor genes to bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America72(9), 3628–3632. PMID: 1059152

Tn7
  • Antibiotic Resistance
  • Streptomycin
  • Trimethoprim
Characteristics
Tn7 (also called TnC) is a 14 kb transposon, found on the plasmid R483. It contains trimethoprim and streptomycin resistance genes.
References

Barth PT, et al. (1976). Transposition of a deoxyribonucleic acid sequence encoding trimethoprim and streptomycin resistances from R483 to other replicons. Journal of Bacteriology125(3), 800–810. PMID: 767328

Accession number
Tn9
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn9 is a 2.6 kb composite transposon, flanked by two direct repeats of insertion sequence IS1. It contains a gene conferring chloramphenicol resistance.
References

Alton, N. K. and D. Vapnek (1979). Nucleotide sequence analysis of the chloramphenicol resistance transposon Tn9. Nature 282(5741): 864-869. doi:10.1038/282864a0

Accession number
Tn10
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn10 is a 9300 bp transposon, flanked by inverted repeats of insertion sequence IS10. This transposon confers tetracycline resistance via tetA.
References

Foster TJ, et al. (1981) Genetic organization of transposon Tn10. Cell 23(1): 201-213. doi: 10.1016/0092-8674(81)90285-3

Chalmers R, et al. (2000). Complete Nucleotide Sequence of Tn10Journal of Bacteriology182(10), 2970–2972. doi: 10.1128/JB.182.10.2970-2972.2000

Accession number
Tn21
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn21 is a 19.7 kb transposon, which contains mercury resistance (mer) operon, integron In2, IS1326 and IS1353. In2 carries aadA1 (conferring resistance to streptomycin and spectinomycin) on a gene cassette and sul1 gene on its 3′-conserved region.
References

Liebert CA, et al. (1999) Transposon Tn21, flagship of the floating genomeMicrobiol. Mol. Biol. Rev.63:507–522 PMID: 10477306 

Accession number
Tn45
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn45 is a 2.4 kb transposon, found on plasmid pXZ10145 from Corynebacterium glutamicum. It contains gene conferring chloramphenicol resistance.
References

Ren Z, et al. (2004) Complete nucleotide sequence analysis of two corynebacterial plasmids pXZ10142 and pXZ10145 containing a transposon-like sequence Tn45. Journal of Fudan University, Natural Science 43, 200–205. Link: http://en.cnki.com.cn/Article_en/CJFDTotal-FDXB200402012.htm

Shen T, et al. (1993). "Determination of nucleotide sequence of Corynebacterium plasmid pXZ10145." Chin J Biotechnol 9(3): 171-178. PMID: 8049348

Accession number
Tn55
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn55 contains a gene conferring kanamycin resistance. This transposon is identical to Tn601 and Tn903.
References

Cohen SN, et al. (1980) Transposable genetic elements. Sci Am 242(2): 40-49. doi: 10.1038/scientificamerican0280-40

Tn71
  • Antibiotic Resistance
  • Streptomycin
  • Trimethoprim
Characteristics
Tn71 is identical to Tn7, containing trimethoprim and streptomycin resistance genes. It was located on plasmid R721.
References

Barth PT, et al. (1977) Two Naturally Occurring Transposons Indistinguishable from Tn7. Microbiology 102(1): 129-134. doi: 10.1099/00221287-102-1-129

Accession number
Tn72
  • Antibiotic Resistance
  • Streptomycin
  • Trimethoprim
Characteristics
Tn72 is identical to Tn7, containing trimethoprim and streptomycin resistance genes. It was located on plasmid pBW1.
References

Barth PT, et al. (1977) Two Naturally Occurring Transposons Indistinguishable from Tn7. Microbiology 102(1): 129-134. doi: 10.1099/00221287-102-1-129

Tn76
  • Antibiotic Resistance
  • Streptomycin
  • Trimethoprim
Characteristics
Tn76 is closely related to Tn7 and confers resistance to trimethoprim and streptomycin. It was located on plasmid pRP761.
References

Barth PT, et al. (1984). Involvement of kil and kor genes in the phenotype of a host-range mutant of RP4. Molecular and General Genetics MGG 197(2): 236-243. doi: 10.1007/BF00330969

Tn125
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn125 is 10,099 bp transposon encoding a NDM-1 carbapenemase found in Acinetobacter baumannii.
References

Poirel, L., et al(2012). Tn125-Related Acquisition of blaNDM-Like Genes in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy56(2), 1087–1089. DOI: 10.1128/AAC.05620-11

Accession number
Tn163
Characteristics
Tn163 is a 4.6 kb transpsosn located on endogenous plasmids and was identified in Rhizobium leguminosarum bv. viciae. This transposon is characterised by the presence of 38 bp terminal inverted repeats. Tn163 encodes a transposase and a resolvase.
References

Ulrich, A., & Pühler, A. (1994). The new class 11 transposon Tn163 is plasmid-borne in two unrelated Rhizobium leguminosarum biovar viciae strains. Molecular and General Genetics MGG242(5), 505-516. DOI: https://link.springer.com/article/10.1007/BF00285274

Accession number
Tn501
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn501 is a 8.3 kb transposon detected on plasmid pVS1 from Pseudomonas aeruginosa which encodes mercuric ion resistance determinants.
References
Bennett, P. M., Grinsted, J., Choi, C. L., & Richmond, M. H. (1978). Characterisation of Tn501, a transposon determining resistance to mercuric ions. Molecular and General Genetics MGG, 159(1), 101-106. Link: https://link.springer.com/article/10.1007/BF00401753
Accession number
Tn502
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn502 is a 9.6 kb transposon detected on plasmid pVS6 of Pseudomonas aeruginosa. This transposon carries a mer operon that confers resistance to mercury.
References

Stanisich, V. A., Arwas, R., Bennett, P. M., & De la Cruz, F. (1989). Characterization of Pseudomonas mercury-resistance transposon Tn502, which has a preferred insertion site in RP1. Microbiology135(11), 2909-2915. doi:10.1099/00221287-135-11-2909

 

Accession number
Tn510
  • Antibiotic Resistance
  • Streptomycin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn510 is a 13.3 kb transposn which was found to be located on plasmid R906 of Bordetella bronchiseptica. It carries a mer operon that confers resistance to mercury and two aminoglycoside phosphotransferase genes that encode streptomycin resistant determinants.
References

Petrovski, S., & Stanisich, V. A. (2011). Embedded elements in the IncPβ plasmids R772 and R906 can be mobilized and can serve as a source of diverse and novel elements. Microbiology157(6), 1714-1725. DOI: 10.1099/mic.0.047761-0

Accession number

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