Tn registry

Displaying 21 - 40 of 652
Tn511
  • Antibiotic Resistance
  • Kanamycin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn511 is a 19.0 kb transposon detected on plasmid R772 of Proteus mirabilis. It carries a mercury resistance (mer) operon and an aminoglycoside phosphotransferase gene that confers resistance to kanamycin.
References

Petrovski, S., & Stanisich, V. A. (2011). Embedded elements in the IncPβ plasmids R772 and R906 can be mobilized and can serve as a source of diverse and novel elements. Microbiology157(6), 1714-1725. doi: 10.1099/mic.0.047761-0

Accession number
Tn512
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn512 is a 8.4 kb transposon of the Tn5053-family. It carries a mercury resistance (mer) operon and was detected in clinical strains of Pseudomonas spp.
References

Petrovski, S., Blackmore, D. W., Jackson, K. L., & Stanisich, V. A. (2011). Mercury (II)-resistance transposons Tn502 and Tn512, from Pseudomonas clinical strains, are structurally different members of the Tn5053 family.Plasmid65(1), 58-64. DOI: https://doi.org/10.1016/j.plasmid.2010.08.003

 

Accession number
Tn536
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Trimethoprim
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn536 is an approximately 16 kb transposon that encodes resistance to trimethorpim, spectinomycin, streptomycin, sulfonamides and mercury ions.
References

Tonin, P. N., & Grant, R. B. (1987). Genetic and physical characterization of trimethoprim resistance plasmids from Shigella sonnei and Shigella flexneri.Canadian journal of microbiology33(10), 905-913. DOI:https://doi.org/10.1139/m87-157

Tn551
  • Antibiotic Resistance
  • Erythromycin
Characteristics
Tn551 is a 5.2 kb transposon detected in Staphylococcus aureus. Tn551 is very similar to the enterococcal transposon Tn917 and encodes an erythromycin resistant determinant.
References

Khan, S. A., & Novick, R. P. (1980). Terminal nucleotide sequences of Tn551, a transposon specifying erythromycin resistance in Staphylococcus aureus: homology with Tn3. Plasmid4(2), 148-154. DOI: https://doi.org/10.1016/0147-619X(80)90004-9

WU, S. W., DE LENCASTRE, H. E. R. M. I. N. I. A., & TOMASZ, A. (1999). The Staphylococcus aureus transposon Tn 551: complete nucleotide sequence and transcriptional analysis of the expression of the erythromycin resistance gene. Microbial Drug Resistance5(1), 1-7. DOI: https://doi.org/10.1089/mdr.1999.5.1

Accession number
Tn552
  • Antibiotic Resistance
  • Penicillin
Characteristics
Tn552 is a 6.5 kb transposon found in Staphylococcus aureus which encodes beta-lactam resistant determinants.
References

Rowland, S. J., & Dyke, K. G. (1989). Characterization of the staphylococcal beta-lactamase transposon Tn552. The EMBO journal8(9), 2761. PMCID: PMC401285

Rowland, S. J., & Dyke, K. G. H. (1990). Tn552, a novel transposable element from Staphylococcus aureus. Molecular microbiology4(6), 961-975. DOI: 10.1111/j.1365-2958.1990.tb00669.x

Accession number
Tn554
  • Antibiotic Resistance
  • Erythromycin
  • Spectinomycin
Characteristics
Tn554 is a 6.7 kb transposon found in Staphylococcus aureus. It encodes erythromycin and spectinomycin resistant determinants.
References

Phillips, S., & Novick, R. P. (1979). Tn554—a site-specific represser-controlled transposon in Staphylococcus aureus. Nature278(5703), 476-478. DOI:10.1038/278476a0

Murphy, E., Huwyler, L., & de Freire Bastos, M. D. C. (1985). Transposon Tn554: complete nucleotide sequence and isolation of transposition-defective and antibiotic-sensitive mutants. The EMBO journal4(12), 3357. PMCID: PMC554666

Accession number
Tn558
  • Antibiotic Resistance
  • Chloramphenicol
  • Florfenicol
Characteristics
Tn558 is a 6.6 kb transposon which carries a florfenicol-chloramphenicol efflux gene, fexA and a putative oxidoreductase gene. It is a member of Tn554 family of staphylococcal transposons. It was detected on plasmid pSCFS2 of Staphylococcus lentus.
References

Kehrenberg, C., & Schwarz, S. (2005). Florfenicol-chloramphenicol exporter gene fexA is part of the novel transposon Tn558. Antimicrobial agents and chemotherapy49(2), 813-815. doi:  10.1128/AAC.49.2.813-815.2005

Kehrenberg, C., & Schwarz, S. (2004). fexA, a novel Staphylococcus lentus gene encoding resistance to florfenicol and chloramphenicol. Antimicrobial agents and chemotherapy48(2), 615-618. doi:  10.1128/AAC.48.2.615-618.2004

Accession number
Tn559
  • Antibiotic Resistance
  • Trimethoprim
Characteristics
Tn559 is a 4.2 kb transposon related to Tn554. The erm(A) and spc resistance genes of Tn554 were replaced by dfrK in Tn559. Tn559 was detected in Staphylococcus aureus ST398 strain and found to be integrated in the chromosomal radC gene. Tn559 was also detected in different species of Enterococci.
References

Kadlec, K., & Schwarz, S. (2010). Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. Antimicrobial agents and chemotherapy54(8), 3475-3477. doi:  10.1128/AAC.00464-10

López, M., Kadlec, K., Schwarz, S., & Torres, C. (2012). First detection of the staphylococcal trimethoprim resistance gene dfrK and the dfrK-carrying transposon Tn 559 in enterococci. Microbial Drug Resistance18(1), 13-18. doi:https://doi.org/10.1089/mdr.2011.0073

Accession number
Tn601
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn601 is identical to Tn55 and Tn903, which contains a kanamycin resistance gene.
References

Oka A. et al. (1981). Nucleotide sequence of the kanamycin resistance transposon Tn903. J Mol Biol 147(2): 217-226. doi: 10.1016/0022-2836(81)90438-1

Romanova IuM, et al. (1980). Transposition of the kanamycin resistance determinant (Tn601) from plasmid 5T to the genome of bacteriophage lambda and the expression of this gene after prophage induction Genetika 16(2): 199-204. PMID: 6444394

Tn602
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn602 is highly homologous to Tn903. It contains kanamycin resistance gene, which is flanked by direct repeats of IS602.
References

Stibitz S, et al. (1987). Tn602: a naturally occurring relative of Tn903 with direct repeats. Plasmid 17(3): 202-209. doi: 10.1016/0147-619X(87)90028-X

Accession number
Tn610
  • Antibiotic Resistance
  • Sulphonamide
Characteristics
Tn610 is a composite transposon (flanked by IS6100), isolated from Mycobacterium smegmatis. It was likely to derive from an In4-like integron. This transposon confers resistance to sulfonamides, via suf3 (encoding dihydropterate synthase).
References

Martin C, et al. (1990) Transposition of an antibiotic resistance element in mycobacteria. Nature 345(6277): 739-743. doi: 10.1038/345739a0

Accession number
Tn611
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn611 is modified from Tn610 by replacing sul3 gene with aph(3') from Tn903, which confers kanamycin resistance.
References

Perez E, et al. (1998). "Tn611 transposon mutagenesis in Mycobacterium smegmatis using a temperature-sensitive delivery system." Methods Mol Biol 101: 187-198. doi: 10.1385/0-89603-471-2:187

Tn654
  • Antibiotic Resistance
  • Ampicillin
  • Kanamycin
  • Streptomycin
Characteristics
Tn654 is closely related to Tn1331 and belongs to the Tn3 family. It was identified from the conjugative plasmid pBWH302. It contains aac(6')-lb', aadA, and bla genes, conferring resistance to amikacin, streptomycin and ampicillin, respectively.
References

Hopkins JD, et al. (1991). Nosocomial spread of an amikacin resistance gene on both a mobilized, nonconjugative plasmid and a conjugative plasmid. Antimicrobial Agents and Chemotherapy35(8), 1605–1611. doi: 10.1128/AAC.35.8.1605

Tn679
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn679 is a composite transposon, which contains a kanamycin resistance gene flanked by an intact IS679 sequence and an IS679 fragment.
References

Han CG, et al. (2001). Structural and Functional Characterization of  IS679 and IS66-Family Elements. Journal of Bacteriology183(14), 4296–4304. doi: 10.1128/JB.183.14.4296-4304.2001

Tn701
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn701 is a 8.5 kb transposon, conferring tetracycline resistance. It was identified from plasmid R446b
References

Minakhina S, et al. (1999) Tn5053 family transposons are res site hunters sensing plasmidal res sites occupied by cognate resolvases. Mol Microbiol 33(5): 1059-1068. doi: 10.1046/j.1365-2958.1999.01548.x

Mindlin SZ, et al. (1996). Incorporation of Tn5053 and Tn402 into various plasmids. Genetika 32(10): 1426-1430. PMID: 9091418

Tn732
  • Antibiotic Resistance
  • Gentamicin
Characteristics
Tn732 is a transposon found on the plasmid pHH1313b, conferring gentamycin/tobramycin resistance.
References

Nugent ME, et al. (1979) A transposon, Tn732, encoding gentamicin/tobramycin resistance. Nature 282(5737): 422-423. doi: 10.1038/282422a0

Tn733
  • Antibiotic Resistance
  • Gentamicin
Characteristics
Tn733 contains a gene encoding the gentamicin acetyltransferase AAC(3), which was found on plasmid pHH1302 and pHH1307.
References

Nugent ME, et al. (1980). Transposable gentamicin resistance in IncW plasmids from Hammersmith Hospital. J Gen Microbiol 121(1): 259-262. doi: 10.1099/00221287-121-1-259

Tn734
  • Antibiotic Resistance
  • Gentamicin
Characteristics
Tn734 is identical to Tn733. It was designated as Tn733 which transposed from plasmid pHH1302-1 to plasmid R388.
References

Nugent ME, et al. (1980). Transposable gentamicin resistance in IncW plasmids from Hammersmith Hospital. J Gen Microbiol 121(1): 259-262. doi: 10.1099/00221287-121-1-259

Tn735
  • Antibiotic Resistance
  • Trimethoprim
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn735 is related to Tn21, which was identified from plasmid pHH502-1. It contains genes conferring mercury and trimethoprim resistance.
References

Smith CA, et al. (1987) Narrow-host-range IncP plasmid pHH502-1 lacks a complete IncP replication system. J Gen Microbiol 133(8): 2247-2252. doi: 10.1099/00221287-133-8-2247

Tn800
  • Antibiotic Resistance
  • Gentamicin
  • Kanamycin
  • Neomycin
  • Sulphonamide
Characteristics
Tn800 was found on plasmid R1535, which confers resistance to aminoglycoside and sulphonamide.
References

Hedges RW, et al. (1984) Resistance to apramycin in Escherichia coli isolated from animals: detection of a novel aminoglycoside-modifying enzyme. J Gen Microbiol 130(3): 473-482. doi: 10.1099/00221287-133-8-2247

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