Tn registry

Displaying 101 - 120 of 652
Tn1826
  • Antibiotic Resistance
  • Streptothricin
Characteristics
Tn1826 is very similar to Tn1825 which carries a streptothricin resistance determinant.
References

Tietze, E., Brevet, J., & Tschäpe, H. (1987). Relationships among the streptothricin resistance transposons Tn1825 and Tn1826 and the trimethoprim resistance transposon Tn7. Plasmid, 18(3), 246-249. DOI: 10.1016/0147-619X(87)90067-9

Tn1831
  • Antibiotic Resistance
  • Spectinomycin
  • Streptomycin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn1831 encodes resistance to streptomycin, spectinomycin as well as mercury.
References

Hooykaas, P. J. J., den Dulk-Ras, H., & Schilperoort, R. A. (1980). Molecular mechanism of Ti plasmid mobilization by R plasmids: isolation of Ti plasmids with transposon-insertions in Agrobacterium tumefaciens.Plasmid4(1), 64-75. DOI:0.1016/0147-619X(80)90083-9

Tn1935
  • Antibiotic Resistance
  • Ampicillin
  • Kanamycin
  • Spectinomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn1935 is a 23.5 kb transposon, which is isolated from pZM3 plasmid from Salmonella wien. It composes of an entire Tn21 (19.7 kb: spectinomycin, sulfonamide and mercury resistance genes) with an insertion of ampicillin resistance gene (0.95 kb) and another fragment, which contains direct repeats of IS1936, flanking kanamycin resistance gene.
References

Colonna, B., et al. (1988). The Salmonella wien virulence plasmid pZM3 carries Tn1935, a multiresistance transposon containing a composite IS1936-kanamycin resistance element. Plasmid 20(3): 221-231. DOI: 10.1016/0147-619X(88)90028-5

Tn1999
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn1999 is a composite transposon carrying two IS1999 elements flanking blaOXA-48 and transcriptional regulator lysR genes.
References

Aubert D, et al. (2006). Functional Characterization of IS1999, an IS4 Family Element Involved in Mobilization and Expression of β-Lactam Resistance Genes. Journal of Bacteriology188(18), 6506–6514. DOI: 10.1128/JB.00375-06

Accession number
Tn2000
  • Antibiotic Resistance
  • Ampicillin
  • Chloramphenicol
  • Gentamicin
  • Kanamycin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • Antispetic Resistance
  • CTAB
Characteristics
Tn2000 is a composite transposon, which contains inverted repeats of IS26 elements, flanking a truncated class 1 integron In53. The In53 integron carries eight resistance genes, which are sul1, blaVEB-1, aadB, arr-2, cmlA, qac, aacA1b, oxa10 and aadA1.
References

Naas T, et al. (2001). Characterization of In53, a Class 1 Plasmid- and Composite Transposon-Located Integron of Escherichia coli Which  Carries an Unusual Array of Gene Cassettes. Journal of Bacteriology183(1), 235–249. DOI: 10.1128/JB.183.1.235-249.2001

Accession number
Tn2001
  • Antibiotic Resistance
  • Chloramphenicol
Characteristics
Tn2001 is isolated from plasmid Rms159-1 in Pseudomonas aeruginosa. It carries gene conferring chloramphenicol resistance.
References

Iyobe, S., Sagai, H., & Mitsuhashi, S. (1981). Tn2001, a transposon encoding chloramphenicol resistance in Pseudomonas aeruginosa. Journal of Bacteriology146(1), 141–148. PMID: 6260739

Tn2003
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn2003 is a 9.5-kb composite transposon. It has direct repeats of IS26 elements, flanking blaSHV-5.
References

Preston, K. E., et al. (2014). "The complete nucleotide sequence of the multi-drug resistance-encoding IncL/M plasmid pACM1." Plasmid 76: 54-65. DOI: 10.1016/j.plasmid.2014.08.005

Accession number
Tn2006
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn2006 is an ISAba1-based composite transposon with a size of 4.8 kb. Inverted repeats of ISAba-1 elements flank a blaOXA-23 gene.
References

Corvec S, et al. (2007). Genetics and Expression of the Carbapenem-Hydrolyzing Oxacillinase Gene blaOXA-23in Acinetobacter baumannii . Antimicrobial Agents and Chemotherapy51(4), 1530–1533. DOI: 10.1128/AAC.01132-06

Accession number
Tn2007
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn2007 is a 2.5-kb transposon, which includes blaOXA-23 and ISAba4 element.
References

Corvec S, et al. (2007). Genetics and Expression of the Carbapenem-Hydrolyzing Oxacillinase Gene blaOXA-23in Acinetobacter baumannii . Antimicrobial Agents and Chemotherapy51(4), 1530–1533. DOI: 10.1128/AAC.01132-06

Accession number
Tn2008
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn2008 is similar to a composite transposon Tn2006. It contains blaOXA-23 gene with only one copy of ISAba1 element (while Tn2006 carried two ISAba1 elements).
References

Nigro, S. and R. M. Hall (2015). Distribution of the blaOXA-23-containing transposons Tn2006 and Tn2008 in Australian carbapenem-resistant Acinetobacter baumannii isolates. J Antimicrob Chemother 70(8): 2409-2411. DOI: 10.1093/jac/dkv102

Accession number
Tn2009
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn2009 is a Tn916-like element with an insertion of mef(E)-carrying element mega (macrolide efflux genetic assembly; 5,511 bp) at orf6 of Tn916. By carrying tet(M) and mef(E) genes, it confers tetracycline and erythromycin resistances, respectively.
References

Liu LL, et al. (2015). Dissemination of blaOXA-23 in Acinetobacter spp. in China: Main Roles of Conjugative Plasmid pAZJ221 and Transposon Tn2009Antimicrobial Agents and Chemotherapy59(4), 1998–2005. DOI: 10.1128/AAC.04574-14

 

Accession number
Tn2010
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn2010 is a 26.4-kb Tn916-like element with an insertion of mef(E)-carrying element mega (macrolide efflux genetic assembly (in ORF6 like in Tn2009) and erm(B) gene (in the ORF20).
References

Li, Y., et al. (2011). "Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010." J Appl Microbiol 110(1): 254-265. DOI: 10.1111/j.1365-2672.2010.04875.x

Accession number
Tn2011
  • Antibiotic Resistance
  • Ampicillin
  • Streptomycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2011 is designated to transposon on plasmid RMs213, conferring ampicillin, streptomycin sulfonamide and mercury resistance. Its ampicillin resistance is conferred by blaOXA-1 gene.
References

Nakazawa, H., & Mitsuhashi, S. (1983). Tn2011, a new transposon encoding oxacillin-hydrolyzing beta-lactamase. Antimicrobial Agents and Chemotherapy23(3), 407–412. DOI: 10.1128/AAC.23.3.407

Tn2012
  • Antibiotic Resistance
  • Quinalone
Characteristics
Tn2012 is a 2.7-kb transposon, identified on the pR4525 natural plasmid in Escherichia coli R4525, which contains ISRcp1C and qnrB19 gene. It was inserted into orf1 gene of Tn1721.
References

Cattoir V, et al. (2008). ISEcp1-Mediated Transposition of qnrB-Like Gene in Escherichia coli . Antimicrobial Agents and Chemotherapy52(8), 2929–2932.  DOI: 10.1128/AAC.00349-08

 

 

 

 

Accession number
Tn2016
  • Antibiotic Resistance
  • Carbapenem
  • Penicillin
Characteristics
Tn2016 is a 4.4-kb transposon, isolated from a Klebsiella pneumoniae clinical isolate. It contains ISkpn15 and blaOXA-204 gene. ISEcp1 is also found as a part of Tn2016, but was disrupted by ISkpn15.
References

Potron A, et al. (2013). Characterization of OXA-204, a Carbapenem-Hydrolyzing Class D β-Lactamase from Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy57(1), 633–636. DOI: 10.1128/AAC.01034-12

Accession number
Tn2017
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn2017 is a 28.5 composite transposon, identified in Streptococcus pneumoniae. It is a Tn916-like element with an insertion of Tn917 in orf9 and mega element (macrolide efflux genetic assembly) in orf6.
References

Del Grosso M, et al. (2009). New Composite Genetic Element of the Tn916 Family with Dual Macrolide Resistance Genes in a Streptococcus pneumoniae Isolate Belonging to Clonal Complex 271 . Antimicrobial Agents and Chemotherapy53(3), 1293–1294. DOI: 10.1128/AAC.01066-08

Accession number
Tn2020
Characteristics
Tn2020 is a 4.1-kb transposon bound by IS2020 and a truncated IS2020. It contains two ORFs, which both encode for hypothetical proteins (one is similar to transmembrane transporter protein).
References

Halling, S. M. and R. L. Zuerner (2002). "Evidence for lateral transfer to Brucellae: characterization of a locus with a Tn-like element (Tn2020)." Biochim Biophys Acta 1574(1): 109-116. DOI: 10.1016/S0167-4781(01)00352-9

Accession number
Tn2101
  • Antibiotic Resistance
  • Ampicillin
  • Spectinomycin
  • Streptomycin
  • Sulphonamide
  • carbenicillin
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn2101 is found on plasmid Rms433 in Enterobacter cloacae. It carries genes conferring carbenicillin, streptomycin, sulphanilamide, spectinomycin, mercury resistance.
References

Katsu, K., Inoue, M., & Mitsuhashi, S. (1982). Transposition of the carbenicillin-hydrolyzing beta-lactamase gene. Journal of Bacteriology150(2), 483–489. PMID: 6279559 

Tn2301
  • Antibiotic Resistance
  • Ampicillin
Characteristics
Tn2301 is a 44.5 kb transposon which carries an ampicillin resistance determinant.
References

Johnson, D. A., & Willetts, N. S. (1980). Tn2301, a transposon construct carrying the entire transfer region of the F plasmid. Journal of Bacteriology,143(3), 1171-1178. PMCID: PMC294470

Tn2350
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn2350 is a 10.4 kb transposon which confers resistance to kanamycin. It is flanked by two directly repeated copies of IS1 element.
References

Clerget, M., Chandler, M., & Caro, L. (1980). Isolation of an IS1 flanked kanamycin resistance transposon from R1drd19. Molecular and General Genetics MGG180(1), 123-127. DOI: 10.1007/BF00267360

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