The Transposon Registry

Displaying 2021 - 2040 of 2136
Tn7712
Dr Yuxia Zhong
Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China
  • Antibiotic Resistance
  • Amoxicillin
  • Ampicillin
Characteristics
Tn7712 is a 15017bp transposon, flanked by inverted repeats of insertion sequence ISkpn19. This transposon confers beta-lactam resistance via blakpc-2. The blaKPC-2 gene was located in an ISKpn19-orf1-orf2-Tn3-ISKpn27-blaKPC-2-ISKpn6-orf2-orf1-ISKpn19 structure.
Accession number
Contact
Tn7713
Janko Sattler
Tn7714
Ivan Munoz Gutierrez
University of California, Irvine
Characteristics
Tn7714 is a 22.6 Kb transposon that is a Tn21 and Tn1721 hybrid. Tn7714 contains the resolution site, tnpR, tpnA, tetR, tetA (tetracycline resistance), and delta-tnpA from Tn1721 (99% identical). The mercury resistance operon (merR, merT, merP, merC, merA, merD, and merE), urf2, intI1, and tnpM are from Tn21 (99-100% identical). The intI1 integron carries the trimethoprim resistance gene dfrA5. An IS26 composite transposon between the mercury resistance operon and the intI1 integron carries resistance genes for aminoglycosides (strB, strA) and sulfamethoxazole (sul2). Tn7714 was found in an IncF plasmid (NZ_CP107285.1) from an Escherichia coli (GCA_025808215.1) isolated from a Baton Rouge, Louisiana lake. During a conjugation experiment, Tn7714 moved from the IncF plasmid into a cryptic IncX plasmid, creating a new multidrug resistance IncX plasmid (NZ_CP110861.1).
References

Muñoz-Gutiérrez I, Cantu L, Shanahan J, Girguis M, de la Cruz M, Mota-Bravo L. 2024. Cryptic environmental conjugative plasmid recruits a novel hybrid transposon resulting in a new plasmid with higher dispersion potential. mSphere 0:e00252-24.
https://doi.org/10.1128/msphere.00252-24

Accession number
Contact
Tn7715
yang liuyang
Tn7716
yang liuyang
Tn7717
yang liuyang
Tn7718
yang liuyang
Tn7719
yang liuyang
Tn7720
Ms. Suhanya Prasad
Tn7721
Ms. Suhanya Prasad
Tn7722
MD Huynh Ngoc Tram VO
Tn7723
Romina Papa Ezdra
Tn7724
Prof Dr Stefan Schwarz
Tn7725
Prof Dr Stefan Schwarz
Tn7726
Prof Dr Stefan Schwarz
Tn7727
Prof Dr Stefan Schwarz
Tn7728
Prof Dr Stefan Schwarz
Tn7729
Prof Dr Stefan Schwarz
Tn7730
Prof Dr Stefan Schwarz
Tn7731
Prof Dr Stefan Schwarz

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