Tn registry

Displaying 181 - 200 of 904
Tn3871
  • Antibiotic Resistance
  • Erythromycin
Characteristics
Tn3871 is a 5.1 kb transposon related to Tn917 which encodes resistance to erythromycin.
References

Banai, M. E. N. A. C. H. E. M., & LeBlanc, D. J. (1984). Streptococcus faecalis R plasmid pJH1 contains an erythromycin resistance transposon (Tn3871) similar to transposon Tn917. Journal of Bacteriology158(3), 1172-1174. Link: http://jb.asm.org/content/158/3/1172.short

Tn3872
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn3872 is a composite transposon which was originally detected in Streptococcus pneumoniae and was generated by insertion of Tn917 into Tn916 orf9. It encodes resistance to tetracycline and erythromycin.
References

Poyart, C., Quesne, G., Acar, P., Berche, P., & Trieu-Cuot, P. (2000). Characterization of the Tn916-like transposon Tn3872 in a strain of Abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child. Antimicrobial agents and chemotherapy,44(3), 790-793. DOI: 10.1128/AAC.44.3.790-793.2000

Tn3926
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn3926 is a 7.8-kb Tn21-like transposon, found in Yersinia enterocolitica YE138A14. It contains tnpA, tnpR and mercury resistance operon.
References

Osbourn, S. E., et al. (1995). Nucleotide sequence within Tn3926 confirms this as a Tn21-like transposable element and provides evidence for the origin of the mer operon carried by plasmid pKLH2. Plasmid 33(1): 65-69. DOI: 10.1006/plas.1995.1008

Lett, M. C., et al. (1985). Characterization of Tn3926, a new mercury-resistance transposon from Yersinia enterocolitica. Gene 40(1): 79-91. DOI: 10.1016/0378-1119(85)90026-5

Accession number
Tn3951
  • Antibiotic Resistance
  • Chloramphenicol
  • Erythromycin
  • Tetracycline
Characteristics
Tn3951 is a 65-kb chromosomal conjugative elements, isolated from Streptococcus pneumoniae. It carries multiple resistance genes, conferring resistance to chloramphenicol, erythromycin and tetracycline.
References

Le Bouguénec, C., de Cespédès, G., & Horaud, T. (1990). Presence of chromosomal elements resembling the composite structure Tn3701 in streptococci. Journal of Bacteriology172(2), 727–734. DOI: 10.1128/jb.172.2.727-734.1990

Vijayakumar MN, et al. (1986). Structure of a conjugative element in Streptococcus pneumoniae. Journal of Bacteriology166(3), 978–984. DOI: 10.1128/jb.166.3.978-984.1986

Tn4000
  • Antibiotic Resistance
  • Gentamicin
  • Kanamycin
  • Sulphonamide
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn4000 is a Tn21-related element, containing mer, sul, aadA, and aadB genes.
References

Schmidt, F. R., et al. (1988). "Nucleotide sequence analysis of 2''-aminoglycoside nucleotidyl-transferase ANT(2'') from Tn4000: its relationship with AAD(3'') and impact on Tn21 evolution." Mol Microbiol 2(6): 709-717. DOI: 10.1111/j.1365-2958.1988.tb00081.x

Accession number
Tn4001
  • Antibiotic Resistance
  • Gentamicin
  • Kanamycin
Characteristics
Tn4001 is a 4.7 kb composite transposon that mediates resistance to gentamicin, tobramycin and kanamycin. It was detected on different structurally-related plasmids of Staphylococcus aureus.
References

Gillespie, M. T., Lyon, B. R., Messerotti, L. J., & Skurray, R. A. (1987). Chromosome-and plasmid-mediated gentamicin resistance in Staphylococcus aureus encoded by Tn4001. Journal of Medical Microbiology24(2), 139-144.DOI: 10.1099/00222615-24-2-139

Mahairas, G. G., Lyon, B. R., Skurray, R. A., & Pattee, P. A. (1989). Genetic analysis of Staphylococcus aureus with Tn4001. Journal of Bacteriology,171(7), 3968-3972. DOI10.1128/jb.171.7.3968-3972.1989

Accession number
Tn4002
  • Antibiotic Resistance
  • Penicillin
Characteristics
Tn4002 is a 6.7 kb transposon encoding resistance to penicillin via beta-lactamase, blaZ in multiresistant Staphylococcus aureus.
References

Gillespie, M. T., & Skurray, R. A. (1989). Nucleotide sequence of the blaZ gene of the Staphylococcus aureus β-lactamase transposon Tn4002. Nucleic Acids Research17(21), 8854-8854. PMCID: PMC335048

Tn4003
  • Antibiotic Resistance
  • Trimethoprim
Characteristics
Tn4003 is a 4.7 kb composite transposon encoding resistance to trimethoprim via a dfrA gene. It was detected in plasmid pSK1 of Staphylococcus aureus.
References

Rouch, D. A., Messerotti, L. J., Loo, L. S. L., Jackson, C. A., & Skurray, R. A. (1989). Trimethoprim resistance transposon Tn4003 from Staphylococcus aureus encodes genes for a dihydrofolate reductase and thymidylate synthetase flanked by three copies of IS257. Molecular Microbiology3(2), 161-175. DOI: 10.1111/j.1365-2958.1989.tb01805.x

Accession number
Tn4031
  • Antibiotic Resistance
  • Gentamicin
Characteristics
Tn4031 is a 5.0 kb composite transposon related to Tn4001. It encodes resistance to gentamicin. It was detected in plasmid pGO221 of S. epidermidis.
References

Thomas, W. D., & Archer, G. L. (1989). Mobility of gentamicin resistance genes from staphylococci isolated in the United States: identification of Tn4031, a gentamicin resistance transposon from Staphylococcus epidermidis. Antimicrobial Agents and Chemotherapy33(8), 1335-1341.PMCID: PMC172650

Tn4132
  • Antibiotic Resistance
  • Trimethoprim
Characteristics
Tn4132 is a transposon related to Tn7 with an approxomate size of 16.0 kb. It encodes resistance to trimethoprim via a dhfrIb gene.
References

Young, H. K., Qumsieh, M. J., & Mclntosh, M. L. (1994). Nucleotide sequence and genetic analysis of the type Ib trimethoprim-resistant, Tn 4132-encoded dihydrofolate reductase. Journal of Antimicrobial Chemotherapy34(5), 715-725. DOI: https://doi.org/10.1093/jac/34.5.715

 

Tn4176
  • Antibiotic Resistance
  • Ceftazidime
Characteristics
Tn4176 is a composite transposon similar to Tn1213. It carries a blaPER-1 gene which confers resistance to ceftazidime. It is located within another 14 kb transposon called Tn5393d.
References

Mantengoli, E., & Rossolini, G. M. (2005). Tn5393d, a complex Tn5393 derivative carrying the PER-1 extended-spectrum β-lactamase gene and other resistance determinants. Antimicrobial Agents and Chemotherapy,49(8), 3289-3296. DOI: doi: 10.1128/AAC.49.8.3289-3296.2005

Tn4201
Characteristics
Tn4201 is a 6.7-kb transposon found on the conjugative plasmid pCRG1600 in Staphylococcus aureus. It contains blaZ gene, conferring penicillin resistance.
References

Weber, D. A., & Goering, R. V. (1988). Tn4201, a beta-lactamase transposon in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy32(8), 1164–1169. DOI: 10.1128/AAC.32.8.1164

Tn4291
  • Antibiotic Resistance
  • Methicillin
Characteristics
Tn4291 is found on the plasmid pI524 from Staphylococcus aureus. It carries genes confer resistance to methicillin.
References

Trees, D. L., & Iandolo, J. J. (1988). Identification of a Staphylococcus aureus transposon (Tn4291) that carries the methicillin resistance gene(s). Journal of Bacteriology170(1), 149–154. DOI: 10.1128/jb.170.1.149-154.1988

Tn4321
Characteristics
Tn4321 is a composite transposon found on plasmid R751. It carries orf1 and orf2 genes, flanked by inverted repeats of IS4321.
References

Thorsted, P. B., et al. (1998).Complete sequence of the IncPbeta plasmid R751: implications for evolution and organisation of the IncP backbone. J Mol Biol 282(5): 969-990. DOI: 10.1006/jmbi.1998.2060

Accession number
Tn4351
  • Antibiotic Resistance
  • Erythromycin
  • Tetracycline
Characteristics
Tn4351 is a composite transposon found in plasmid pBF4 from Bacteroides fragilis. It contains tetracycline resistance gene (expressed in Bacteroides but in not E. coli) and erythromycin resistance genes (expressed in aerobically grown E. coli but not Bacteroides), flanked by IS4351 elements.
References

Hoover, C. I., et al. (1992). Transposition of Tn4351 in Porphyromonas gingivalis. Plasmid 27(3): 246-250. DOI: 10.1016/0147-619X(92)90028-9

Accession number
Tn4352
  • Antibiotic Resistance
  • Kanamycin
Characteristics
Tn4352 is a 2.68-kb composite transposon, found on the plasmid NTP16 from Salmonella typhimurium. It contains gene, encoding aminoglycoside 3’-phosphotransferase (APH) protein, which is flanked by direct repeats of IS176 (identical to IS26).
References

Wrighton, C. J. and P. Strike (1987). A pathway for the evolution of the plasmid NTP16 involving the novel kanamycin resistance transposon Tn4352. Plasmid 17(1): 37-45. DOI: 10.1016/0147-619X(87)90006-0

Accession number
Tn4371
  • Metabolism
  • Biphenyl degradation
Characteristics
Tn4371 is a 55-kb transposon, isolated from Ralstonia eutropha A5. It contains bph catabolic gene cluster, a Pseudomonas-like catabolic genes, which involves in biphenyl degradation.
References

Merlin, C., et al. (1999). Tn4371: A modular structure encoding a phage-like integrase, a Pseudomonas-like catabolic pathway, and RP4/Ti-like transfer functions. Plasmid 41(1): 40-54. DOI: 10.1006/plas.1998.1375

Accession number
Tn4378
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn4378 is found on plasmid pMOL28 from Ralstonia metallidurans CH34. It contains mercury resistance operon (merRTPADE), tnpA and tnpR genes.
References

Champier, L., et al. (2004). Characterization of the MerD protein from Ralstoniametallidurans CH34: a possible role in bacterial mercury resistance by switching off the induction of themer operon. Mol Microbiol 52(5): 1475-1485. DOI: 10.1111/j.1365-2958.2004.04071.x

Accession number
Tn4380
  • Heavy Metal Resistance
  • Mercury Resistance
Characteristics
Tn4380 is found on plasmid pMOL30 from Ralstonia metallidurans CH34. It contains mercury resistance operon (merRTPADE), tnpA and tnpR genes.
References

Champier, L., et al. (2004). Characterization of the MerD protein from Ralstoniametallidurans CH34: a possible role in bacterial mercury resistance by switching off the induction of themer operon. Mol Microbiol 52(5): 1475-1485. DOI: 10.1111/j.1365-2958.2004.04071.x

Accession number
Tn4399
Characteristics
Tn4399 is a 9.6-kb conjugal transposon from Bacteroides fragilis. It contains a 2.8-kb mobilisation cassette (mocA and mocB gene).
References

Murphy, C. G., & Malamy, M. H. (1993). Characterization of a “mobilization cassette” in transposon Tn4399 from Bacteroides fragilis. Journal of Bacteriology175(18), 5814–5823. DOI: 10.1128/jb.175.18.5814-5823.1993

Hecht, DW, et al. (1989). Characterization of the termini and transposition products of Tn4399, a conjugal mobilizing transposon of Bacteroides fragilis. Proceedings of the National Academy of Sciences of the United States of America86(14), 5340–5344. DOI: 10.1128/jb.171.7.3603-3608.1989

Accession number

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