The Transposon Registry

Displaying 561 - 580 of 2071
Tn6247
Prof Du Xiang-Dang
Henan Agricultural University
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6247 is a 23.7-kb Tn5397-like element, found in Enterococcus faecium isolate P39. It contained 21 ORFs, including tet(M), tet(L), tndX and an insertion of IS1216E.
References
Du,X.-D. and Wang,X.-M. (Unpublished) Tn6247, a novel Tn5397-like element located on a large conjugative plasmid in enterococci of swine origin
Accession number
Contact
xiangdangdu@gmail.com
Tn6248
Prof Du Xiang-Dang
Henan Agricultural University
  • Antibiotic Resistance
  • Chloramphenicol
  • Tetracycline
Characteristics
Tn6248 is 26-kb Tn5397-like conjugative transposon isolated from Enterococcus faecium strain E506. It was similar to Tn6247, which carried tet(M) tet(L) and tnpX, but Tn6248 also carried tnpA (IS110-family transposase) and cat gene, conferring chloramphenicol resistance.
References

Gawryszewska I, Żabicka D, Hryniewicz W, Sadowy E. Linezolid-resistant enterococci in Polish hospitals: species, clonality and determinants of linezolid resistance. European Journal of Clinical Microbiology & Infectious Diseases. 2017;36(7):1279-1286. DOI: 10.1007/s10096-017-2934-7.

Du,X.-D. (Unpublished) Tetracycline and chloramphenicol resistance gene cluster tet(M)-tet(L)-cat was linked on a novel mobile genetic element, Tn6248
Accession number
Contact
xiangdangdu@gmail.com
Tn6249
Dr VINCENZO DI PILATO
UNIVERSITY OF SIENA
  • Antibiotic Resistance
  • Carbapenem
  • Chloramphenicol
  • Kanamycin
  • Streptomycin
  • Sulphonamide
Characteristics
Tb6249 is a 26-kb Tn6162-derived transposon found in Pseudomonas aeruginosa strain VR-143/97. It carried two ISPa7 elements, an In70.2 integron platform (associated with a defective Tn402-like transposon inserted into the urf2 gene of a Tn3 family transposon of Tn6162), a partially deleted mer operon and an In90 integron platform. Several resistance genes were found as part of the In70.2 and In90 integrons including blaVIM-1, aacA4, aphA15, aadA1, sul1 in In70.2, and sul1 catB10, aacA4 in In90.
References

Di Pilato V, Pollini S, Rossolini GM. Tn6249, a New Tn6162 Transposon Derivative Carrying a Double-Integron Platform and Involved with Acquisition of the blaVIM-1 Metallo-β-Lactamase Gene in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 2015;59(3):1583-1587. DOI: 10.1128/AAC.04047-14.

Accession number
Contact
vdipilato@unisi.it
Tn6250
Prof H. Howard Xu
California State University, Los Angeles
  • Antibiotic Resistance
  • Streptomycin
  • Sulphonamide
Characteristics
Tn6250 is a 12.8-kb composite transposon, found in Acinetobacter baumannii strain LAC-4. It composed of two ISAba1 elements at the ends, and an IS1006 internally next to a partial ISVsa3 element. It also carried genes for conjugal transfer functions (TraA and TraD) and resistance genes for streptomycin (strA and strB) and for sulphonamides (sul2).
References

Ou H-Y, Kuang SN, He X, et al. Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. Scientific Reports. 2015;5:8643. DOI: 10.1038/srep08643.

Accession number
Contact
hxu3@calstatela.edu
Tn6251
Prof H. Howard Xu
California State University, Los Angeles
Characteristics
Tn6251 is a 5.2-kb composite transposon found in Acinetobacter baumannii strain LAC-4. It composed of two ISAba1 elements at the ends, flanking four genes [including appB and appC genes].
References

Ou H-Y, Kuang SN, He X, et al. Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. Scientific Reports. 2015;5:8643. DOI: 10.1038/srep08643.

Accession number
Contact
hxu3@calstatela.edu
Tn6252
Prof H. Howard Xu
California State University, Los Angeles
  • Antibiotic Resistance
  • Carbapenem
Characteristics
Tn6252 is a 2.7-kb composite transposon, found in Acinetobacter baumannii strain LAC-4. It composed of two ISAba1 elements at the ends,flanking blaOXA-235 resistance gene.
References

Ou H-Y, Kuang SN, He X, et al. Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. Scientific Reports. 2015;5:8643. DOI: 10.1038/srep08643.

Accession number
Contact
hxu3@calstatela.edu
Tn6253
Prof Samer Kayal
Université Rennes1-CNRS-UMR 6290
  • Antibiotic Resistance
  • Tetracycline
Characteristics
Tn6253 is a 20.7-kb Tn916-like conjugative transposon, found in Streptococcus pyogenes M/emm44 Strain STAB901. It contains tetM gene conferring tetracycline resistance and a 2.6-kb group II integron inserted in Tn916-orf16.
References

Soriano, N., Vincent, P., Piau, C., Moullec, S., Gautier, P., Lagente, V., … Kayal, S. (2014). Complete Genome Sequence of Streptococcus pyogenes M/emm44 Strain STAB901, Isolated in a Clonal Outbreak in French Brittany. Genome announcements, 2(6), e01174-14. DOI: 10.1128/genomeA.01174-14

Accession number
Contact
samer.kayal@chu-rennes.fr
Tn6254
Mr Yasuhiro Tanizawa
National Institute of Genetics
  • Heavy Metal Resistance
  • Mercury Resistance
  • Metabolism
  • Glutathione synthesis
Characteristics
Tn6254 is a 52 kb-length putative integrated and conjugative element of Lactobacillus hokkaidonensis. It shares several components with other Lactobacilli such as L. vini, L. nodensis, L. paracasei, and L. coryniformis. It contained genes encoding proteins for conjugation, DMP synthase, phage resistance, glutathione synthase, cell wall protein and mercury resistance.
References

Tanizawa Y, Tohno M, Kaminuma E, Nakamura Y, Arita M. Complete genome sequence and analysis of Lactobacillus hokkaidonensis LOOC260T, a psychrotrophic lactic acid bacterium isolated from silage. BMC Genomics. 2015;16(1):240. DOI: 10.1186/s12864-015-1435-2.

Accession number
Contact
ytanizaw@nig.ac.jp
Tn6255
Dr Alberto Antonelli
University of Florence
  • Antibiotic Resistance
  • Carbapenem
  • Penicillin
Characteristics
Tn6255 is a 4-kb Tn402/Tn5053 hybrid transposon derivative located within Tn6256, which was found in Citrobacter freundii strain Cfr-FI-07. It contained remnants of the tniR to that of Tn402/Tn5090 and remnants of the tniA gene identical to that of Tn5053, separated by an IS26. It also carried blaOXA372 gene, conferring resistance to penicillins, including temocillin, and reduced susceptibility to carbapenems.
References

Antonelli, A., et al. (2015). "OXA-372, a novel carbapenem-hydrolysing class D beta-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant." J Antimicrob Chemother 70(10): 2749-2756. DOI: 10.1093/jac/dkv181

Accession number
Contact
albertoanton88@gmail.com
Tn6256
Dr Alberto Antonelli
University of Florence
  • Antibiotic Resistance
  • Carbapenem
  • Penicillin
Characteristics
Tn6256 is a 12.9-kb transposon found in Citrobacter freundii strain Cfr-FI-07. It composed of Tn6255 [carrying blaOXA-372] inserted into TnPa38 [a Tn3-family tranposon], which were all flanking by two IS5075-like elements.
References

Antonelli, A., et al. (2015). "OXA-372, a novel carbapenem-hydrolysing class D beta-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant." J Antimicrob Chemother 70(10): 2749-2756. DOI: 10.1093/jac/dkv181

Accession number
Contact
albertoanton88@gmail.com
Tn6257
Dr Ho Pak Leung
The University of Hong Kong
Contact
plho@hkucc.hku.hk
Tn6258
Prof Xiang-Dang Du
Henan Agricultural University
Contact
xddu@henau.edu.cn
Tn6259
Prof Xiang-Dang Du
Henan Agricultural University
Contact
xddu@henau.edu.cn
Tn6260
Prof Xiang-Dang Du
Henan Agricultural University
  • Antibiotic Resistance
  • Lincomycin
Characteristics
Tn6260 is a 4.7-kb transposon found in Enterococcus faecalis strain E531. It contained tnpA, tnpB, tnpC and lincosamide nucleotidyltransferase (lnu(G)) genes.
References

Zhu, X. Q., et al. (2017). "Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531." J Antimicrob Chemother 72(4): 993-997. DOI: 10.1093/jac/dkw549

Accession number
Contact
xddu@henau.edu.cn
Tn6261
Prof Xiang-Dang Du
Henan Agricultural University
  • Antibiotic Resistance
  • Erythromycin
  • Florfenicol
  • Oxazolidinone
Characteristics
Tn6261 is an 8.9-kb transposon, found in Enterococcus faecalis strain E260. It contained tnpA, tnpB, optrA (ABC transporter ATP-binding protein that confers resistance to oxazolidinones and phenicols) and erm(A).
References

Sun, C., et al. (2018). "Presence and molecular characteristics of oxazolidinone resistance in staphylococci from household animals in rural China." J Antimicrob Chemother 73(5): 1194-1200. DOI: 10.1093/jac/dky009

Accession number
Contact
xddu@henau.edu.cn
Tn6262
Prof Xiang-Dang Du
Henan Agricultural University
  • Antibiotic Resistance
  • Erythromycin
  • Lincomycin
  • Spectinomycin
  • Streptogramin A
  • Streptomycin
  • Tiamulin
Accession number
Contact
xddu@henau.edu.cn
Tn6263
Dr Frédéric Pecorari
University of Nantes
  • Antibiotic Resistance
  • Erythromycin
  • Kanamycin
  • Streptomycin
Characteristics
Tn6263 is a 46-kb Tn916-like conjugative transposon, found in Streptococcus gallolyticus subsp. gallolyticus strain NTS 31106099. It contained about 50 coding sequences, including an aminoglycoside/macrolide resistance cluster [aph(3′)-III→ant(6)-Ia→ermB].
References

Kambarev S, Caté C, Corvec S, Pecorari F. Draft Genome Sequence of Erythromycin-Resistant Streptococcus gallolyticus subsp. gallolyticus NTS 31106099 Isolated from a Patient with Infective Endocarditis and Colorectal Cancer. Genome Announcements. 2015;3(2):e00370-15. DOI: 10.1128/genomeA.00370-15.

Accession number
Contact
frederic.pecorari@univ-nantes.fr
Tn6264
Dr Jee Eun Han
University of Arizona
  • Virulence Determinants
  • Toxin production
Characteristics
Tn6264 is a 5.5-kb composite transposon, found in plasmid pVA from Vibrio parahaemolyticus. It contained two ISVal1 elements, flanking pirAVp and pirBVp genes (encoding insect-related (Pir) toxins PirAVp and PirBVp).
References

iwsaiya K, Charoensapsri W, Taengphu S, et al. A Natural Vibrio parahaemolyticus ΔpirAVp pirBVp+ Mutant Kills Shrimp but Produces neither PirVp Toxins nor Acute Hepatopancreatic Necrosis Disease Lesions. Dozois CM, ed. Applied and Environmental Microbiology. 2017;83(16):e00680-17. DOI: 10.1128/AEM.00680-17.

Accession number
Contact
jeehan@email.arizona.edu
Tn6265
Dr Sadjia Bekal
INSPQ
Contact
sadjia.bekal@inspq.qc.ca
Tn6266
Miss Wang Na
Shanghai Jiaotong University
Contact
wangn@sjtu.edu.cn

Pages